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MCQ_Sem3_MINI1 - Hypersensitivity quiz assesses understanding of hypersensitivity reactions, focusing on mechanisms and clinical implications. Key topics include Type IV hypersensitivity, differences between hypersensitivity...

Questions: 12 | Attempts: 2045 | Last updated: Aug 18, 2025

Sample Question 1
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The ability of this organism to cause disease is related to it’s ability to infect, persist in, and replicate within macrophages. The lepromin skin test is used to determine what type of leprosy a person has. In this test, inactivated Mycobacterium leprae organisms are injected just beneath the skin. At the site of injection, a person with a positive test will develop an area of induration with erythema peaking around 48 hours after the injection. If this test measures a hypersens4tivity reaction against the organism, what type of hypersensitivity reaction is it intended to detect?

Type I

Type IV

Type II

Type U or 111

Type III

Sample Question 2
The principle difference between type II and type III hypersensitivity is:

The class (isotype of antibody)

Whether the antibody reacts with the antigen on the cell or reacts with antigen before it interacts with the cell

The participation of complement

The participation of T cells

Sample Question 3
A child stung by a bee experiences respiratory distress within minutes and lapses into unconsciousness. This reaction is probably mediated by:

IgE antibody

IgG antibody

Sensitized T cells

Complement

IgM antibody