Liver Pathology / Vascular Abnormalities Of The Liver(Portal Hypertension Only)
Questions and Answers
- 1.
__________ hypertension is increased blood pressure within the portal vein.
Explanation
Portal hypertension refers to increased blood pressure within the portal vein, which is the vein that carries blood from the digestive organs to the liver. This condition can occur due to various reasons such as liver cirrhosis, liver diseases, or blockage in the blood flow within the liver. Elevated pressure in the portal vein can lead to complications like varices (enlarged veins), ascites (fluid accumulation in the abdomen), and hepatic encephalopathy (brain dysfunction). Therefore, the term "portal" accurately describes the type of hypertension mentioned in the question.Rate this question:
- 2.
Portal hypertension is increased _________ to blood.
Explanation
Portal hypertension is a condition characterized by increased pressure in the portal venous system. This can occur due to various factors, such as liver cirrhosis or blockage of the portal vein. The increased resistance to blood flow in the portal system leads to the development of collateral vessels and can result in complications like variceal bleeding. Therefore, the correct answer is "resistance" as it accurately describes the increased opposition to blood flow in the portal system.Rate this question:
- 3.
The normal PV diameter is how many mm? (#)
Explanation
The question asks for the normal diameter of the PV, and the answer is 11 mm. This suggests that the normal diameter of the PV is 11 mm.Rate this question:
- 4.
The PV diameter is considered abnormal when it measures ____ mm. (#)
Explanation
The PV diameter is considered abnormal when it measures 13 mm. This suggests that a PV diameter of 13 mm is outside the normal range and may indicate an abnormality or pathology.Rate this question:
- 5.
The diameter of PV may return to normal even if portal hypertension still exists.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
It is possible for the diameter of the portal vein (PV) to return to normal even if portal hypertension still exists. Portal hypertension is characterized by increased blood pressure in the portal vein, which can lead to the enlargement of the PV. However, with proper treatment and management of the underlying cause of portal hypertension, the blood pressure in the PV can be reduced, allowing the diameter of the PV to return to normal. Therefore, it is true that the diameter of PV may return to normal even if portal hypertension still exists.Rate this question:
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- 6.
This type of portal hypertension is caused by something outside the liver, not involving the sinusoids. This type of portal hypertension is known as __________ _____________ .
Correct Answer
extrahepatic presinusoidal
extrahepatic presinusoidal portal hypertensionExplanation
Extrahepatic presinusoidal portal hypertension is a type of portal hypertension that is caused by factors outside the liver, which do not involve the sinusoids. In this condition, the increased pressure in the portal vein is due to an obstruction or narrowing of the blood vessels before they reach the liver. This can occur as a result of conditions such as portal vein thrombosis or compression of the portal vein by a tumor or fibrosis.Rate this question:
- 7.
Extrahepatic presinusoidal PHTN is caused by portal or splenic vein ________, or from occlusion or compression of the portal vein or splenic vein.
Correct Answer
thrombosisExplanation
Extrahepatic presinusoidal PHTN refers to a type of portal hypertension that occurs outside the liver, specifically before the blood reaches the sinusoids. This condition can be caused by various factors such as portal or splenic vein thrombosis, which refers to the formation of blood clots within these veins. Alternatively, occlusion or compression of the portal vein or splenic vein can also lead to extrahepatic presinusoidal PHTN.Rate this question:
- 8.
____________ ______________ PHTN is when the cause is within the liver but not involving the sinusoids.
Correct Answer
intrahepatic presinusoidalExplanation
Intrahepatic presinusoidal refers to a condition where the cause of liver damage or dysfunction is located within the liver itself, but it does not involve the sinusoids. The sinusoids are small blood vessels in the liver that play a crucial role in blood flow and filtration. In this specific condition, the liver damage occurs before the blood reaches the sinusoids. This explanation clarifies that "intrahepatic presinusoidal" accurately describes the condition where the cause is within the liver but does not involve the sinusoids.Rate this question:
- 9.
Intrahepatic presinusoidal PHTN is caused by lesions or obstruction in the portal zone.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Intrahepatic presinusoidal PHTN refers to a condition where there is increased pressure in the blood vessels within the liver, specifically in the portal zone. This increased pressure is caused by lesions or obstruction in the portal zone, which can impede the flow of blood through the liver. Therefore, the statement that intrahepatic presinusoidal PHTN is caused by lesions or obstruction in the portal zone is true.Rate this question:
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- 10.
Check all of the following examples that apply to intrahepatic sinusoidal PTHN:
- A.
Schistosomiasis
- B.
Kaposi's sarcoma
- C.
Primary hepatic fibrosis
- D.
Toxic substances such as methotrexate
- E.
Primary biliary cirrhosis
- F.
Pneumocystis carinii
Correct Answer(s)
A. Schistosomiasis
C. Primary hepatic fibrosis
D. Toxic substances such as methotrexate
E. Primary biliary cirrhosisExplanation
Intrahepatic sinusoidal portal hypertension (PTHN) is a condition characterized by increased pressure in the portal vein within the liver, leading to liver dysfunction. Schistosomiasis is a parasitic infection that can cause liver damage and contribute to the development of PTHN. Primary hepatic fibrosis is a chronic liver disease characterized by the progressive scarring of the liver, which can lead to PTHN. Toxic substances such as methotrexate, a chemotherapy drug, can cause liver damage and contribute to PTHN. Primary biliary cirrhosis is an autoimmune disease that affects the bile ducts in the liver and can lead to PTHN. Kaposi's sarcoma and pneumocystis carinii are not known to be associated with intrahepatic sinusoidal PTHN.Rate this question:
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- 11.
This type of portal hypertension is associated with hepatocellular disease and metastatic liver disease.
Correct Answer(s)
intrahepatic sinusoidalExplanation
Intrahepatic sinusoidal portal hypertension refers to increased pressure in the blood vessels within the liver. It is associated with hepatocellular disease, which includes conditions that affect the liver cells themselves, such as cirrhosis or hepatitis. It is also seen in metastatic liver disease, which occurs when cancer spreads to the liver from other parts of the body. In both cases, the increased pressure in the liver's blood vessels can lead to complications such as varices or ascites.Rate this question:
- 12.
Abnormal liver architecture leads to decreased resistance to flow in the portal veins.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
leads to increased resistance to flow in the portal veinsRate this question:
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- 13.
In cirrhosis, most of the normal liver architecture is replaced and ________.
Correct Answer
distortedExplanation
In cirrhosis, the normal liver architecture is extensively replaced by scar tissue, leading to the distortion of the liver's structure. This distortion disrupts the normal functioning of the liver, affecting its ability to perform essential tasks such as detoxification, metabolism, and production of important proteins.Rate this question:
- 14.
Increased resistance caused by a blockage of blood leaving the liver (venous drainage) is known as ___________ ______________ PHTN.
Correct Answer
intrahepatic post-sinusoidalExplanation
Increased resistance caused by a blockage of blood leaving the liver (venous drainage) is known as intrahepatic post-sinusoidal portal hypertension (PHTN). This condition occurs when there is a blockage or obstruction in the small veins within the liver, leading to increased pressure in the portal vein. This can be caused by various conditions such as liver cirrhosis or thrombosis of the hepatic veins. The increased resistance in the liver can result in complications such as variceal bleeding or ascites.Rate this question:
- 15.
IVC and HV thrombosis (budd chiari), and severe right sided CHF are examples of intrahepatic sinusoidal PHTN.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
they are examples of intrahepatic post-sinusoidal PHTNRate this question:
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- 16.
50-75% of cases of post hepatic PHTN are of __________ etiology.
Correct Answer
unknownExplanation
The correct answer is "unknown" because the question is asking about the etiology (cause) of post hepatic PHTN (portal hypertension). The term "unknown" implies that the cause of this condition is not fully understood or identified. This suggests that there is no specific known cause for the majority of cases of post hepatic PHTN, accounting for 50-75% of the cases.Rate this question:
- 17.
Check all that apply to the clinical presentation of portal hypertension:
- A.
Ascites
- B.
Splenomegaly
- C.
Fibrosis
- D.
Caput medusa
- E.
GI bleeding
Correct Answer(s)
A. Ascites
B. Splenomegaly
D. Caput medusa
E. GI bleedingExplanation
Portal hypertension occurs when there is increased pressure in the portal vein, which carries blood from the digestive organs to the liver. This increased pressure can lead to various clinical presentations. Ascites refers to the accumulation of fluid in the abdominal cavity and can occur due to portal hypertension. Splenomegaly, or enlargement of the spleen, is also commonly associated with portal hypertension. Caput medusa refers to the appearance of dilated veins around the umbilicus, which can be a sign of portal hypertension. GI bleeding can occur as a result of the increased pressure in the portal vein. Fibrosis, or scarring of the liver, is not directly mentioned as a clinical presentation of portal hypertension.Rate this question:
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- 18.
This is caused by esophageal varices, which causes hematemesis, a life threatening condition.
Correct Answer(s)
GI bleedingExplanation
GI bleeding refers to the medical condition where there is bleeding in the gastrointestinal tract. Esophageal varices, which are enlarged veins in the lower part of the esophagus, can be a cause of GI bleeding. When these varices rupture, it can lead to severe bleeding, resulting in hematemesis (vomiting of blood). Hematemesis is a serious and potentially life-threatening symptom that requires immediate medical attention. Therefore, the given answer correctly identifies GI bleeding as the cause of hematemesis, emphasizing the urgency and severity of the condition.Rate this question:
- 19.
________ _______ is a network of abnormal superficial venous channels radiating out of the skin. It is caused by recannalization of the umbilical vein.
Correct Answer(s)
caput medusaExplanation
Caput medusa is a condition characterized by a network of abnormal superficial venous channels radiating out of the skin. This condition occurs due to the recannalization of the umbilical vein. The umbilical vein is a blood vessel that connects the fetus to the placenta during pregnancy. In normal circumstances, this vein closes after birth. However, in cases of liver disease or portal hypertension, the umbilical vein can reopen, leading to the formation of the caput medusa. This condition is named after Medusa, a figure from Greek mythology with snakes for hair, as the appearance of the veins resembles snakes radiating from the umbilicus.Rate this question:
- 20.
Check all that apply to the sonographic findings of portal hypertension:
- A.
Dilated PV
- B.
Hepatofugal blood flow
- C.
Splenomegaly
- D.
Ascites
- E.
Dilated splenic vein or SMV
- F.
Varices
Correct Answer(s)
A. Dilated PV
B. Hepatofugal blood flow
C. Splenomegaly
D. Ascites
E. Dilated splenic vein or SMV
F. VaricesExplanation
The sonographic findings of portal hypertension can include dilated PV (portal vein), hepatofugal blood flow (blood flowing away from the liver), splenomegaly (enlarged spleen), ascites (accumulation of fluid in the abdominal cavity), dilated splenic vein or SMV (superior mesenteric vein), and varices (abnormally enlarged veins). These findings are indicative of increased pressure in the portal venous system, which can occur due to liver cirrhosis or other conditions that obstruct blood flow through the liver.Rate this question:
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- 21.
Name the 5 major sites of collaterals.
Correct Answer(s)
gastroesophageal varices, paraumbilical vein, splenorenal and gastrorenal, intestinal, and hemorrhoidalExplanation
The five major sites of collaterals are gastroesophageal varices, paraumbilical vein, splenorenal and gastrorenal, intestinal, and hemorrhoidal. These sites are areas where collateral blood vessels develop in response to increased pressure in the portal vein system. Gastroesophageal varices are enlarged veins in the lower part of the esophagus and stomach, paraumbilical vein connects the portal vein to the veins around the umbilicus, splenorenal and gastrorenal collaterals connect the splenic and renal veins to the left renal vein, intestinal collaterals develop in the mesentery, and hemorrhoidal collaterals develop around the rectum and anus. These collaterals help to divert blood flow and relieve pressure in the portal vein system.Rate this question:
- 22.
This site of collateral is where the perianal veins anastomose with the middle and inferior rectal veins.
Correct Answer(s)
hemorrhoidalExplanation
The correct answer is "hemorrhoidal". The explanation for this answer is that the site of collateral mentioned in the question refers to the location where the perianal veins connect or join together with the middle and inferior rectal veins. This specific site is commonly associated with hemorrhoids, which are swollen and inflamed blood vessels in the anal area. Therefore, the term "hemorrhoidal" is the most appropriate answer in this context.Rate this question:
- 23.
When the ligamentum teres recannalizes and leads to the caput medusa around the umbilicus on the superficial epidermis, it is termed the :
Correct Answer(s)
paraumbilical veinExplanation
The ligamentum teres is a remnant of the fetal umbilical vein. When it recannalizes and forms a connection between the portal vein and the veins on the superficial epidermis around the umbilicus, it is called the paraumbilical vein. This condition can lead to the development of caput medusa, which refers to the appearance of dilated and tortuous veins around the umbilicus resembling the head of Medusa from Greek mythology.Rate this question:
- 24.
__________________ varices are between the coronary veins, the gastric veins, and the esophageal veins. These varices may lead to life threatening or fatal hemorrhage.
Correct Answer(s)
gastroesophagealExplanation
Gastroesophageal varices are abnormal, enlarged blood vessels that occur in the walls of the lower part of the esophagus and the upper part of the stomach. These varices can develop due to increased pressure in the veins that drain blood from the stomach and esophagus, often as a result of liver disease. When these varices rupture, they can cause severe bleeding, which can be life-threatening or fatal. Therefore, it is important to identify and treat gastroesophageal varices to prevent complications.Rate this question:
- 25.
Regions where the GI tract becomes retroperitoneal, forming a circulation between intraperitoneal and retroperitoneal organs is known as ___________.
Correct Answer(s)
intestinalExplanation
The term "intestinal" refers to the regions where the gastrointestinal (GI) tract becomes retroperitoneal, forming a circulation between intraperitoneal and retroperitoneal organs. This means that these regions of the GI tract are located behind the peritoneum, which is a membrane that lines the abdominal cavity. The retroperitoneal organs include the kidneys, pancreas, and parts of the large intestine. Therefore, the correct answer is "intestinal" because it specifically describes the regions where the GI tract becomes retroperitoneal.Rate this question:
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Mar 20, 2023Quiz Edited by
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Nov 28, 2010Quiz Created by
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