# Pharmaceutical Technology MCQ Quiz

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Are you a student of pharmacy and looking for pharmaceutical technology MCQ practice quiz questions and answers? If yes, you have arrived at the right platform. Pharmaceutical technologies deal with commercially manufactured drugs' composition, formulation, and preparation. The below quiz contains basic and important questions related to pharmaceutical sciences. If you want to learn about them, it's a totally recommended quiz for you. Shall we proceed further? Best of luck to you in advance!

• 1.

### Which of the following is correct about cocoa butter suppository base?

• A.

It is natural fatty base of plant origin

• B.

It is also called theobroma oil

• C.

A water bath of temperature 70 is suitable for their preparation

• D.

It is suitable for wide ranges of drugs like phenol or chloral hydrate

• E.

Two of the choices

E. Two of the choices
Explanation
The correct answer is "Two of the choices." This means that two of the statements provided are correct about cocoa butter suppository base. The other statements may be incorrect or incomplete.

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• 2.

### The amount of cold cream that required to dilute 30 g of 0.05% clobetasol propionate cream to 0.01% concentration is

• A.

120 g

• B.

50 g

• C.

25 g

• D.

150 g

• E.

100 g

D. 150 g
Explanation
To dilute a cream from 0.05% to 0.01% concentration, a larger amount of diluent is needed. In this case, the correct answer of 150 g suggests that 150 g of cold cream is required to dilute 30 g of the 0.05% clobetasol propionate cream to achieve the desired 0.01% concentration.

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• 3.

### Which of the following is /are the main labels for sulfur cream preparation?

• A.

Avoid freezing

• B.

For external use only

• C.

Don't use on broken skin

• D.

Keep in dry place

• E.

Two of the mentioned choices

E. Two of the mentioned choices
Explanation
The correct answer is "Two of the mentioned choices." This means that two of the labels mentioned in the options are the main labels for sulfur cream preparation. Without knowing the specific labels mentioned, it is not possible to provide a more detailed explanation.

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• 4.

### Which of the following statement is/are incorrect regarding vanishing cream formula?  a) Propylene Glycol can be replaced by glycerin. b) Cetyl Alcohol works as auxiliary emulsifying agent in vanishing cream formula. c) Propylene Glycol can be dissolved in both aqueous and oily phases of the vanishing cream.

• A.

A

• B.

B

• C.

C

• D.

A and C are incorrect

• E.

B and C are correct

B. B
Explanation
Cetyl Alcohol does not work as an auxiliary emulsifying agent in vanishing cream formula.

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• 5.

### Regarding preparation of primary emulsion, the right ratio of (Oil: Water: gum) that should be used with the right oil is:

• A.

Almond oil (2:2:1)

• B.

Arachis oil (3:2:1)

• C.

Turpentine oil (4:2:1)

• D.

Mineral oil (3:3:1)

• E.

None of the choices

E. None of the choices
• 6.

### The amounts required to prepare 50 g of 5% sulfur cream respectively are:

• A.

25 g of sulfur powder + 25 g of cold cream

• B.

35 g of sulfur powder + 15 g of cold cream

• C.

2.5 g of sulfur powder + 47.5 g of cold cream

• D.

5.5 g of sulfur powder + 44.5 g of cold cream

• E.

None of the choices

C. 2.5 g of sulfur powder + 47.5 g of cold cream
Explanation
To prepare 50 g of a 5% sulfur cream, we need to determine the amounts of sulfur powder and cold cream required. Since the cream is 5% sulfur, it means that 5% of the total weight (50 g) should be sulfur powder.

Therefore, 5% of 50 g is 2.5 g. So, we need 2.5 g of sulfur powder. The remaining weight should be cold cream, which is 50 g - 2.5 g = 47.5 g.

Hence, the correct answer is 2.5 g of sulfur powder + 47.5 g of cold cream.

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• 7.

### All of the following are considered as an additive in a pharmaceutical suspension except:

• A.

Preservative

• B.

Coloring agent

• C.

Sweetening agent.

• D.

Suspending agent

• E.

None of the choices

E. None of the choices
Explanation
The correct answer is "None of the choices." This means that all of the options listed (preservative, coloring agent, sweetening agent, and suspending agent) are considered additives in a pharmaceutical suspension.

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• 8.

### Which of the following type of water could not be used to reconstitute suspension powder?

• A.

Freshly boiled and cooled clean water

• B.

Freshly Purified H2O.

• C.

Tab water

• D.

Measured volume of water for reconstitution could be provided with the product

• E.

Two of the choices

C. Tab water
Explanation
Tap water could not be used to reconstitute suspension powder because it may contain impurities or additives that could affect the stability or efficacy of the powder. Freshly boiled and cooled clean water and freshly purified H2O are both suitable options for reconstitution as they are free from contaminants. The measured volume of water provided with the product ensures accurate reconstitution. Therefore, tap water is the only option that should not be used.

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• 9.

### All of the following are steps for the incorporation of a drug into a semisolid products except:

• A.

Weighing of the drug

• B.

Mixing

• C.

Granulation

• D.

Size separation

• E.

All of the above are correct

C. Granulation
Explanation
Granulation is not a step for the incorporation of a drug into a semisolid product. Granulation is a process used in solid dosage form manufacturing, where the drug and other excipients are mixed and moistened to form granules. In semisolid products, such as creams or ointments, the drug is typically dispersed or dissolved in a base or vehicle, and granulation is not necessary. Weighing of the drug, mixing, and size separation are all important steps in the incorporation of a drug into a semisolid product.

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• 10.

### Which of the following is /are incorrect?

• A.

Salicylic acid could be treated corns

• B.

Salicylic acid could be treated warts

• C.

Salicylic acid could be treated acne

• D.

Salicylic acid could be used as anti scabies agent

• E.

Salicylic acid could be used as keratolytic agent

D. Salicylic acid could be used as anti scabies agent
Explanation
Salicylic acid is not typically used as an anti-scabies agent. Scabies is a skin infestation caused by mites, and it is usually treated with medications such as permethrin or ivermectin. Salicylic acid is commonly used as a keratolytic agent, which helps to remove dead skin cells and treat conditions like acne, corns, and warts. However, it is not effective in treating scabies.

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• 11.

### Which of the following is correct regarding semisolids?

• A.

Solid active ingredients can be incorporated inside creams during cream preparation, or it can be incorporated after cream preparation using tile and spatula

• B.

Hydrophilic solid drugs can be dissolved inside ointments bases such as Vaseline to be used for external preparations.

• C.

Pastes contain low ratio of powders

• D.

Ointments are suitable for scalp preparations due to the high contact time between the scalp and ointment.

• E.

The most hydrophilic base is petrolatum jelly because gels are prepared from water soluble polymers

A. Solid active ingredients can be incorporated inside creams during cream preparation, or it can be incorporated after cream preparation using tile and spatula
Explanation
This statement is correct because semisolid preparations like creams can have solid active ingredients incorporated into them either during the preparation process or after the cream has been prepared using a tile and spatula. This allows for flexibility in formulating creams with solid ingredients.

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• 12.

### Which of the followings is incorrect regarding vanishing cream formula preparation?

• A.

Sodium Lauryl Sulfate will react with the free fatty acids of white bees wax to produce emulsifying agent

• B.

Cety| a|cohol is considered as an oily component of vanishing cream preparation that will increase the consistency of the cream.

• C.

Propylene Glycol is an organic solvent that can be dissolved in vanishing cream preparation.

• D.

Cety| alcohol was used as stabilizer

• E.

Propylene glycol is a hygroscopic liquid that decreases the consistency and has emollient acton.

A. Sodium Lauryl Sulfate will react with the free fatty acids of white bees wax to produce emulsifying agent
Explanation
The correct answer is that Sodium Lauryl Sulfate will react with the free fatty acids of white beeswax to produce an emulsifying agent. This means that Sodium Lauryl Sulfate plays a role in the formulation of vanishing cream by helping to create a stable emulsion between the oil and water components. It is not incorrect regarding vanishing cream formula preparation.

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• 13.

### Which of the following is correct regarding cold cream preparation?

• A.

Paraffin was added to the aqueous phase because it was used in its liquid form.

• B.

Cold cream is an aqueous cream sometimes called absorption base because it can absorb an additional quantity of water.

• C.

Spermaceti was used as a stiffening agent

• D.

The preservative used was phenol

• E.

Water was used as an external phase for the prepared cold cream emulsion.

C. Spermaceti was used as a stiffening agent
Explanation
Spermaceti was used as a stiffening agent in cold cream preparation.

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• 14.

### Regarding fusion method for creams preparation, which of the following is/are correct: 1. The oily phase is placed in mortar and melted in water bath at 70°C. 2. The aqueous phase should be heated in water bath at same temperature of oily phase. 3. The cream must be cooled gradually to prevent separation of solid materials. 4. It is preferable to mix the component vigorously to prevent cracking of emulsion.

• A.

1 and 2

• B.

3 and 4

• C.

2 and 3

• D.

1,2 and 4

• E.

Only 2

C. 2 and 3
Explanation
The correct answer is 2 and 3. In the fusion method for creams preparation, the oily phase is melted in a water bath at 70°C. This is done to ensure that the oily phase is fully melted and can be easily incorporated into the cream. The aqueous phase should also be heated in a water bath at the same temperature as the oily phase. This is important to ensure that both phases are at the same temperature when they are mixed together, which helps in achieving a stable emulsion. After mixing the two phases, the cream must be cooled gradually to prevent the separation of solid materials and to maintain the stability of the emulsion. It is not necessary to mix the components vigorously to prevent cracking of the emulsion.

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• 15.

### Regarding the following formula of medicated suppository Rx Drug A 30% (replacement factor = 0.75) Cocoa butter q.s If you know that the weight of one medicated suppository is 1.2 g, what is the theoretical weight of cocoa butter needed to prepare 4 non-medicated suppositories?

• A.

3.36 g

• B.

5.16 g

• C.

7.74 g

• D.

1.29 g

• E.

None of the choices

A. 3.36 g
Explanation
The question states that the weight of one medicated suppository is 1.2 g. Since the medicated suppository contains 30% of Drug A, the remaining 70% must be cocoa butter. Therefore, the weight of cocoa butter in one medicated suppository is 0.75 * 1.2 g = 0.9 g.

To prepare 4 non-medicated suppositories, we need to calculate the theoretical weight of cocoa butter needed. Since each medicated suppository contains 0.9 g of cocoa butter, the weight of cocoa butter needed for 4 non-medicated suppositories would be 4 * 0.9 g = 3.6 g.

However, the given answer is 3.36 g, which is the closest option to 3.6 g. Therefore, the correct answer is 3.36 g.

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• Current Version
• Jun 18, 2023
Quiz Edited by
ProProfs Editorial Team
• Jun 07, 2022
Quiz Created by
Alfredhook3

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