White Blood Cell Disorders! Trivia Test! Quiz

32 Questions | Total Attempts: 511

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White Blood Cell Disorders! Trivia Test! Quiz

Do you know anything about white blood cell disorders? White blood cells help defend the body against any questionable materials. White cell blood disorders can affect your body’s immune response and your body’s ability to combat infection, and blood cell disorders interfere with the formation and function of these types of cells. See how much you know about white blood cell disorders and put your knowledge to the test.


Questions and Answers
  • 1. 
    Neutrophils with greater than 5 lobes - Right Shift. Causes: Old cells, chronic inflammation/infection, Anemia, Steroid use.
    • A. 

      Nuclear Hypersegmentation

    • B. 

      Nuclear Hyposegmentation

    • C. 

      Pelger-Huet Anomaly

    • D. 

      Toxic Neutrophils

  • 2. 
    Left Shift - Cells vary from bands to metamyelocytes and myelocytes. With left shifts, we may also see toxic cytoplasm, donut-shaped nuclei, and giant-sized neutrophils. Causes: Seen in inflammatory conditions
    • A. 

      Nuclear Hyposegmentation

    • B. 

      Nuclear Hypersegmentation

    • C. 

      Pelger-Huet Anomaly

    • D. 

      Pseudo-Pelger- Huet Anomaly

  • 3. 
    Congenital defect causing hypopigmentation of granulocytes and monocytes. Calls are mature, Nucleus has condensed chromatin. No segmented neutrophils. Hypopigmented cells function normally.
    • A. 

      Pelger-Huet Anomaly

    • B. 

      Pseudo-Pelger-Huet Anomaly

    • C. 

      Dohle Bodies

    • D. 

      Cytoplasmic Basophilia

  • 4. 
    Fewer hypopigmented cells are seen. Response to severe infection, sometimes a reaction to certain drugs.
    • A. 

      Pseudo-Pelger-Huet Anomaly

    • B. 

      Pelger-Huet Anomaly

    • C. 

      Dohle Bodies

    • D. 

      Vacuolization

  • 5. 
    Associated with conditions such as inflammation, infection and drug toxicity. May occur due to the accelerated production of cells in response to disease. typically accompanied by a left shift.
    • A. 

      Toxic Neutrophils

    • B. 

      Nuclear Hypersegmentation

    • C. 

      Dohle Bodies

    • D. 

      Pyknosis

  • 6. 
    Coarse, Irregular gray-blue cytoplasmic inclusions (RNA) that can be seen singly or in pairs. Common in felines. Found in infections, poisoning, burns, and following chemotherapy.
    • A. 

      Dohle Bodies

    • B. 

      Cytoplasmic Basophilia

    • C. 

      Pyknosis

    • D. 

      Toxic Granules

  • 7. 
    Blue cytoplasm usually is seen with vacuoles. Slightly more severe signs of toxicity. Pale pink cytoplasm to Blue cytoplasm.
    • A. 

      Cytoplasmic Basophilia

    • B. 

      Dohle Bodies

    • C. 

      Toxic Granules

    • D. 

      Pyknosis

  • 8. 
    Recorded as Mild to Severe. Seen as lymphocytes. Cytoplasm a frothy appearance. Artifact if prolonged exposure to EDTA.
    • A. 

      Vacuolization

    • B. 

      Dohle Bodies

    • C. 

      Toxic Granules

    • D. 

      Pyknosis

  • 9. 
    Condensed or Shrunken nucleus, Very dense chromatin. May fragment.
    • A. 

      Pyknosis

    • B. 

      Karyorrhexis

    • C. 

      Karylosis

    • D. 

      Vacuolization

  • 10. 
    Nucleus fragmentation.
    • A. 

      Karyorrhexis

    • B. 

      Pyknosis

    • C. 

      Karyolysis

    • D. 

      Cytoplasmic Basophilia

  • 11. 
    Represents cell death, Nucleus becomes swollen and nuclear membrane degrades
    • A. 

      Karyolysis

    • B. 

      Karyorrhexis

    • C. 

      Pyknosis

    • D. 

      Vacuolization

  • 12. 
    Less Common. Cytoplasmic granules become very prominent.
    • A. 

      Toxic Granules

    • B. 

      Cytoplasmic Basophilia

    • C. 

      Vacuolization

    • D. 

      Dohle Bodies

  • 13. 
    May have crisscross basket weave pattern. Nuclear remnant lacking intact cytoplasm.
    • A. 

      Basket/Smudge Cells

    • B. 

      Toxic Neutrophils

    • C. 

      Pelger-Huet Anomaly

    • D. 

      Pseudo-Pelger-Huet Anomany

  • 14. 
    Gram-Positive coccobacillus. Organism escapes the host vacuole and undergoes rapid division in the cytoplasm before becoming encapsulated where it can migrate to the surface and can penetrate a neighboring cell.
    • A. 

      Listeria

    • B. 

      Ehrilichia

    • C. 

      Anaplasma phagocytophilia

    • D. 

      Histoplasma capsulatum

  • 15. 
    Cytoplasmic parasites of lymphocytes, monocytes, neutrophils, and platelets. Appears as small basophilic clusters in the cytoplasm. Diagnosed best in buffy coat smears.
    • A. 

      Ehrilichia

    • B. 

      Listeria

    • C. 

      Neorickettsia risticii

    • D. 

      Anaplasma phagocytophilia

  • 16. 
    Causes Potomac Fever in Horses. It can affect dogs & cats. Become infected through the ingestion of water insects. Parasitize granulocytes, monocytes & macrophages.
    • A. 

      Neorickettsia risticii

    • B. 

      Listeria

    • C. 

      Anaplasma phagocytophilia

    • D. 

      Histoplasma capsulatum

  • 17. 
    Characterized by Acute Enterocolitis Syndrome. - this can also be found in Salmon Fluke and can be transmitted to humans/animals if ingesting raw fish. Results in hemorrhagic enteritis.
    • A. 

      Potomac Fever

    • B. 

      Halo

    • C. 

      Pseudo-Pelger-Huet Anomaly

    • D. 

      Pelger-Huet Anomaly

  • 18. 
    (Ehrlichia equi) Affects equine neutrophils & eosinophils. Causes canine anaplasmosis - anorexia, lethargy, difficult ambulation.
    • A. 

      Anaplasma phagocytophilia

    • B. 

      Histoplasma capsulatum

    • C. 

      Canine Distemper

    • D. 

      Leishmania infantum

  • 19. 
    Cytoplasmic inclusions in neutrophils, eosinophils, monocytes & macrophages. Yeast seen as small oval cells surrounded by halo, appear in macrophages in tissue samples. Affects people, dogs, cats, sheep, pigs & horses.
    • A. 

      Histoplasma capsulatum

    • B. 

      Neorickettsia risticii

    • C. 

      Mycobacterium species

    • D. 

      Lysome storage

  • 20. 
    Signs of this bacteria is Hepatosplenomegaly, pulmonary disease, lymphadenomegaly, anorexia, depression, conjunctivitis, optic neuritis, and unresponsive pyrexia.
    • A. 

      Histoplasma capsulatum

    • B. 

      Hepatozoon canins

    • C. 

      Canine Distemper

    • D. 

      Mycobacterium species

  • 21. 
    Severe in the US. Transmitted through ticks. Cytoplasmic inclusions in neutrophils & monocytes. They appear as large oblong structures. Signs include anorexia, pyrexia, pale mm, lethargy, diarrhea, lameness, purulent ocular discharge.
    • A. 

      Hepatozoon canis

    • B. 

      Canine Distemper

    • C. 

      Leishmania infantum

    • D. 

      Lysome storage

  • 22. 
    Contagious, Incurable and often fate. A multi-systemic viral disease that affects the respiratory, gastrointestinal and central nervous systems.
    • A. 

      Canine Distemper

    • B. 

      Hepatozoon canis

    • C. 

      Ehrilichia

    • D. 

      Cytauxzoon felis

  • 23. 
    This bacteria is most commonly transmitted through bodily secretions that become airborne viral particles. Signs include pyrexia, discharge from eyes and nose, depression, anorexia, diarrhea, pneumonia, and vomiting.
    • A. 

      Canine Distemper

    • B. 

      Neorickettsia risticii

    • C. 

      Listeria

    • D. 

      Histoplasma capsulatum

  • 24. 
    Recovered dogs from this bacteria may shoe enamel hypoplasia and hyperkeratosis. Infection of fetuses can result in abortion or puppies who develop signs and die within 4 weeks. Large aggregates of viral particles seen in RBCs and WBCs. Transient.
    • A. 

      Canine Distemper

    • B. 

      Hepatozoon canis

    • C. 

      Leishmania infantum

    • D. 

      Chedick-Higashi Syndrome

  • 25. 
    Confirm this bacteria with PCP testing. Appears as unstained rods within the cytoplasm. It affects a wide variety of animals.
    • A. 

      Mycobacterium species

    • B. 

      Lesihmania infantum

    • C. 

      Ehrilichia

    • D. 

      Cytauxzoon felis

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