Day 4: Dry Eye, Sjogren's Syndrome, And Sjo

39 Questions | Total Attempts: 114

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Syndrome Quizzes & Trivia

This quiz has been designed to test your knowledge of dry eye, Sjögren's syndrome, and the new LDT Sjö. You have 1 hour to complete the quiz. A passing grade is a 90% or above.


Questions and Answers
  • 1. 
    True or False:  Only 25% of the patients with Sjögren's syndrome are women.
    • A. 

      True

    • B. 

      False

  • 2. 
    Which of the following is a specific antibody to salivary gland proteins?
    • A. 

      CA-6

    • B. 

      SS-A (Ro)

    • C. 

      SS-B (La)

    • D. 

      ANA

  • 3. 
    Which of the following is an abnormal antibody found in patients with systemic lupus erythematosus?
    • A. 

      SS-B (La)

    • B. 

      Anti-dsDNA

    • C. 

      SP-1

    • D. 

      SS-A (Ro)

  • 4. 
    How many cases of Sjögren's syndrome are thought to be undiagnosed?
    • A. 

      500,000

    • B. 

      1.5 million

    • C. 

      3 million

    • D. 

      6 million

  • 5. 
    Which of the following is NOT considered a traditional biomarker for detecting Sjögren's syndrome?
    • A. 

      ANA

    • B. 

      SP-1

    • C. 

      SS-A (Ro)

    • D. 

      SS-B (La)

  • 6. 
    All of the following are considered proprietary biomarkers for detecting Sjögren's syndrome, except for:
    • A. 

      SP-1

    • B. 

      RF

    • C. 

      PSP

    • D. 

      CA-6

  • 7. 
    Which of the following is NOT an advantage of diagnosing Sjögren's syndrome in the early stages of the disease?
    • A. 

      Increases patients' chances for avoiding many serious complications

    • B. 

      Helps patients receive proper treatment

    • C. 

      Increases patients' chance for a cure

    • D. 

      Helps patients improve their quality of life

  • 8. 
    Which of the following is considered a serious complication of Sjögren's syndrome?
    • A. 

      Neurological problems

    • B. 

      Heart disease

    • C. 

      Diabetes

    • D. 

      Low blood counts

  • 9. 
    What is the rate of sensitivity and specificity for traditional tests for Sjögren's syndrome?
    • A. 

      20%-40%

    • B. 

      40%-60%

    • C. 

      60%-80%

    • D. 

      80%-100%

  • 10. 
    When a patient goes to a third-party lab to have a Sjö test run, who provides the physician with the test results?
    • A. 

      Third-party lab

    • B. 

      RPS

    • C. 

      IMMCO Diagnostics

    • D. 

      LabCorp

  • 11. 
    Who is responsible for billing the patient's insurance company if the blood sample is collected at a third-party lab?
    • A. 

      ECP

    • B. 

      Third-party lab

    • C. 

      IMMCO Diagnostics

    • D. 

      Patient

  • 12. 
    In which journal was the retrospective study by Akpek et al published?
    • A. 

      Clincial Immunology

    • B. 

      British Journal of Ophthalmology

    • C. 

      Cornea

    • D. 

      Clinical Immunology

  • 13. 
    True or False:  The authors of the Shen et al paper concluded that SS-A (Ro), SS-B (La), RF, and ANA are useful markers for identifying patients with Sjögren's syndrome at early stages of the disease.
    • A. 

      True

    • B. 

      False

  • 14. 
    How many patients were included in the study by Akpek et al which evaluated the rate of Sjögren's syndrome in patients with dry eye syndrome?
    • A. 

      186

    • B. 

      220

    • C. 

      362

    • D. 

      414

  • 15. 
    In the study conducted by Akpek et al, what percentage of patients had a combined aqueous and evaporative type of dry eye?
    • A. 

      52.9%

    • B. 

      67.5%

    • C. 

      75.2%

    • D. 

      86.9%

  • 16. 
    In the study conducted by Akpek et al, what percentage of patients with primary Sjögren's syndrome were diagnosed as a result of the initial evaluation?
    • A. 

      50%

    • B. 

      62%

    • C. 

      77%

    • D. 

      83%

  • 17. 
    Of the patients that were diagnosed with Sjögren's syndrome as a result of the initial evaluation during the study conducted by Akpek et al, what percentage tested positive for SS-A (Ro) and SS-B (La) antibodies?
    • A. 

      33.3%

    • B. 

      66.6%

    • C. 

      75.5%

    • D. 

      81.8%

  • 18. 
    Multiple sclerosis is an inflammatory disease that destroys _____.
    • A. 

      Cartilage

    • B. 

      Liver function

    • C. 

      WBCs

    • D. 

      Myelin

  • 19. 
    Anti-Sm is an abnormal antibody found in which of the following diseases?
    • A. 

      Sjögren's syndrome

    • B. 

      Systemic lupus erythematosus

    • C. 

      Rheumatoid arthritis

    • D. 

      Multiple sclerosis

  • 20. 
    Which of the following is NOT a feature of dry eye?
    • A. 

      Inflammation

    • B. 

      Hyperosmolarity

    • C. 

      High TBUT

    • D. 

      Abnormalities of the ocular surface

  • 21. 
    Approximately how many people over age 40 does dry eye affect in the United States?
    • A. 

      4 million

    • B. 

      11 million

    • C. 

      20 million

    • D. 

      40 million

  • 22. 
    If you were suffering with aqueous-deficient dry eye, which of the following might be useful?
    • A. 

      Plaquenil

    • B. 

      Restasis

    • C. 

      Doxycycline

    • D. 

      Voltaren

  • 23. 
    Sjögren's syndrome dry eye and non-Sjögren's syndrome dry eye are subclasses of __________.
    • A. 

      Age-related dry eye

    • B. 

      Evaporative dry eye

    • C. 

      Tear-defective dry eye

    • D. 

      Aqueous-deficient dry eye

  • 24. 
    Which of the following is the most common cause of evaporative dry eye?
    • A. 

      Diabetes

    • B. 

      Aging

    • C. 

      Inflammation

    • D. 

      Meibomian gland dysfunction

  • 25. 
    Which of the following tests can be used for detecting Sjögren's syndrome?
    • A. 

      Lactoferrin

    • B. 

      Sjö

    • C. 

      Ap4A

    • D. 

      Lysozyme