Pace Quiz 1 Part 2

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Pace Quiz 1 Part 2 - Quiz

Questions and Answers
  • 1. 
    A 63-year-old man presents to your office with the following lesion. The biopsy of this large ulcerated area confirmed a squamous cell carcinoma. Where would the cancer cells from this lesion directly metastasize to? 
    • A. 

      Superficial inguinal nodes

    • B. 

      Deep inguinal nodes

    • C. 

      Internal iliac nodes

    • D. 

      Lumbar nodes

    • E. 

      External iliac nodes

  • 2. 
    The cell type at the arrow contains what chromosome and chromatid number?
    • A. 

      23, 1N

    • B. 

      46, 2N

    • C. 

      None, it is a Sertoli cell

    • D. 

      46, 4N

    • E. 

      A & B

    • F. 

      B & C

  • 3. 
    I am a structure in the male reproductive tract.  I am composed of tubuloalveolar glands and I secrete a clear mucous-like secretion that helps to coat the urethra to prepare for ejaculation.  What am I?
    • A. 

      Ejaculatory duct

    • B. 

      Bulbourethral gland

    • C. 

      Seminal vesicle

    • D. 

      Prostate gland

    • E. 

      Epididymis

  • 4. 
    The BCR-ABL gene is involved in causing:
    • A. 

      Alzheimer in Down syndrome

    • B. 

      The specific sound of the cry in Cri-du-Chat

    • C. 

      Cell growth in leukemias

    • D. 

      Polydactyly in Patau syndrome

    • E. 

      Hyperactivity in XYY syndrome

  • 5. 
    The following pedigree shows a family segregating for Duchenne Muscular Dystrophy (DMD).  Individual II-1 was found to have a deletion of exons 45-48 of the dystrophin gene.  Individual II-3 is currently pregnant with a boy. She shows an elevated CK but she tested negative for this mutation (exon 45-48).  The risk for the pregnancy III-2 to have DMD is closest to?
    • A. 

      0%

    • B. 

      10%

    • C. 

      50%

    • D. 

      75%

    • E. 

      100%

  • 6. 
    Although II-3 tested negative for the mutation seen in her brother, the physician is concerned regarding the persistent CK level of II-3.  The pregnancy was tested again and showed a deletion of exon 45-48 considered consistent with being affected with DMD. The most likely explanation is?
    • A. 

      Laboratory error in the testing of II-3

    • B. 

      Non maternity

    • C. 

      Non paternity

    • D. 

      Somatic mosaicism of III-2

    • E. 

      De Novo mutation in III-2

  • 7. 
    A 33 year old man presents to a clinic complaining of infertility.  He previously fathered a child with another woman, but explains that he and his wife have been having unprotected intercourse for the past 14 months and have been unable to get pregnant.  Multiple semen analyses taken two weeks apart reveal oligospermia (sperm count 40,000 sperm/mL) with normal motility.  Testosterone levels are in the normal range.  Which hormone is most likely reduced in this man? 
    • A. 

      Luteinizing hormone

    • B. 

      Prolactin

    • C. 

      Gonadotropin releasing hormone

    • D. 

      Dihydrotestosterone

    • E. 

      Follicle stimulating hormone

    • F. 

      B & D

    • G. 

      D & E

  • 8. 
    A 28 year old woman visits the gynecologist complaining of irregular menstrual cycles.  Her cycles over the past year have been occurring every 7-10 weeks.  Menstrual bleeding lasts for 3-5 days and there is no associated pain.  Plasma levels of estradiol and progesterone are in the normal range for the luteal phase of the menstrual cycle.  Urinalysis is negative for chorionic gonadotropin (hCG); pelvic exam is unremarkable.  Which one of the following descriptions best defines this woman’s menstrual periods?
    • A. 

      Oligomenorrhea

    • B. 

      Dysmenorrhea

    • C. 

      Amenorrhea

    • D. 

      Polymenorrhea

    • E. 

      Menorrhagia

  • 9. 
    During which phase of the menstrual cycle does estrogen concentration increase markedly to stimulate the release of the gonadotropins?
    • A. 

      Mid proliferative

    • B. 

      Mid secretory

    • C. 

      Late secretory

    • D. 

      Menses

    • E. 

      Late proliferative

  • 10. 
    A 62-year-old man complains to his physician that he frequently feels the urge to urinate, but then he has trouble starting the flow and is sometimes troubled by dribbling when he has finished urinating. His prostate gland is found to be significantly enlarged, and following additional tests, benign prostatic hyperplasia is diagnosed. The physician prescribes a drug to help prevent further enlargement of the prostate and possibly to help reduce the size. Which of the following drugs was most likely prescribed?
    • A. 

      Testosterone enanthate

    • B. 

      Flutamide

    • C. 

      Leuprolide

    • D. 

      Finasteride

    • E. 

      Medroxyprogesterone

  • 11. 
    A 25-year-old woman is conferring with her gynecologist regarding treatment options for debilitating endometriosis.  She wishes to have children in the future and hopes to get her endometriosis under control without further compromising her fertility. They decide to try depot injections of leuprolide for the next 6 months and then re-evaluate the condition.  In addition, the physician prescribes a low dose combined oral contraceptive preparation. What is the most likely reason for adding the low-dose OC?
    • A. 

      To prevent pregnancy during exposure to leuprolide

    • B. 

      To maintain normal menstrual periods

    • C. 

      To maintain body weight

    • D. 

      To prevent hypotension

    • E. 

      To prevent bone loss

  • 12. 
    In the accompanying photomicrograph of the ovary, the structures indicated by the pointer produce which of the following hormones?
    • A. 

      Androstenedione

    • B. 

      Estrogen

    • C. 

      LH

    • D. 

      Progesterone

    • E. 

      HCG

  • 13. 
    The structures indicated by the pointer in the accompanying photomicrograph can be derived from which of the following structures? (Choose the one best answer)
    • A. 

      Primordial, primary follicles and secondary follicles

    • B. 

      Primordial, primary, secondary, Graafian follicles, corpus luteum

    • C. 

      Primordial, primary, secondary, and Graafian follicles (*)

    • D. 

      Primordial, primary, secondary, Graafian follicles, corpus luteum, and corpus albicans

    • E. 

      Primordial, primary, secondary, Graafian follicles, corpus luteum, corpus albicans, and interstitial glands

  • 14. 
    Which of the following characterizes the changes in the endometrium in the luteal phase of the menstrual cycle?
    • A. 

      Ischemia and necrosis of the stratum functionale

    • B. 

      Influenced mainly by progesterone

    • C. 

      Starting upon arrival of ovulation

    • D. 

      Presence of straight tubular glands

    • E. 

      Necrosis and sloughing off of the endocervix

  • 15. 
    A syndrome is known to cause excessive height, reduced IQ, and the cells exhibit 2 Barr bodies. Which karyotype is compatible with the above description?  
    • A. 

      45X

    • B. 

      47XXX

    • C. 

      46XX, del(5p)

    • D. 

      47XXY

    • E. 

      47XYY

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