Match the type of steroid hormone to its structural features.
Testosterone exhibits poor bioavailability due to extensive 1st pass...
Order the hormones in the synthesis of estradiol.
Match the drug to its classification/mechanism.
Match the following structural features to the adrenocorticoids they...
Match the hydrocortisone ester to its route of administration.
How much cortisol is secreted by the body under stress compared to...
Match the disease or condition to its treatment.
Match the glucocorticoid synthesis inhibitor with its mechanism of...
Isomers that exist in equilibrium and are readily interconverted by...
Match the receptor binding type to its level of intrinsic activity at...
Match the histamine receptor subtype to its location.
Match the receptor type to the effects observed when the receptor is...
Match the first generation antihistamine to its classification.
Match the second generation antihistamine to its classification.
Finasteride and Dutasteride act by which of the following mechanisms?
The drug-drug interaction between antibiotics and estrogens is due to...
The purpose of the addition of the 17-alpha alkyne group to this...
Suicide inhibition is another name for which type of binding,...
Select two answers. Glucocorticoids mainly enhances which TWO of the...
The steroid molecule shown here is transformed by which of the...
Esterases metabolize lipophilic esters found at C17 on steroid...
The antiandrogens Bicalutamide, Flutamide and Nilutamide act by...
What type of reaction is shown here?
Cortisol is mainly metabolized by which of the following organs?
Which of the following is NOT a symptom of Addison's Disease?
Promethazine has antiemetic effects and can be used in combination to...
The 2nd generation piperadine antihistamine Terfenadine was removed...
Another name for leukotrienes is slow reacting substance of...
Steroids bind receptors ____
The enzyme which catalyzes the Phase 2 reaction of estradiol shown...
The reaction shown here occurs in Phase ___ and is catalyzed by the...
Selective Estrogen Receptor Modulators, or SERMs, act as agonists for...
Match the hormone to the part of the adrenal gland that secretes it.
Dutasteride blocks the conversion of Testosterone to which of the...
Spironolactone reverses the effects of aldosteronism and acts as a...
The interconversion shown here is an example of which of the...
Codeine and morphine displace mast cell granules.
Fexofenadine is a non-cardiotoxic metabolite of Terfenadine....
Which of the following is NOT an adverse effect of Ipratropium, an...
Zileuton inhibits which of the following enzymes?
The anticholinergic effects of antihistamines and other drugs are...
5-alpha Reductase inhibitors, such as Dutasteride, are irreversible...
Which feature of the molecule shown here is very rarely found in drug...
The structure shown here is produced by metabolism of Estrogen by...
The follicular phase of menstruation involves the conversion of...
The most potent endogenous glucocorticoid is _____ while the most...
Steroids are transported in the blood via transport proteins. Which of...
Which of the following enzymes catalyzes the reaction shown here?
A substituent attached to the 10 Carbon on the steroid nucleus shown...
Which of the following are Phase 2 reactions undergone by Estrogens?
Which of the following enzymes is responsible for enterohepatic...
11-deoxycorticosterone is converted to Aldosterone in the Zona...
The enzyme Aromatase produces 17b-estradiol from which of the...
90% of Cortisol in the body can be found where?
Deoxycorticosterone (DOC) is a precursor to aldosterone. Adrenal...
First generation molecules, like the diphenhydramine shown here,...
Why is the nitro group found in antiandrogens such as Nilutamide and...
SERMs, such as Clomifene and Tamoxifen, act by which of the following...
Progestins reduce the risk of cancer from estrogen therapy and...
A 17-Beta Ketol group, which may or may not be esterified, is a MUST...
Synthesis of histamine from histidine is which type of reaction?
Bioisosteres are chemical groups with similar physical and chemical...
The function of the enzyme Aromatase is to de-aromatize the A ring of...
One example of a drug-drug interaction involving competition for...
Cortisone is a prodrug of Hydrocortisone. The conversion of cortisone...
Histamine promotes wakefulness
Estrogens have an aromatic A ring, 18 Carbons and a 3-OH group. Which...
People with parasitic diseases are more likely to develop allergies...
The purpose of esterification of steroid molecules with long carbon...
The rightward reaction shown in this pictures is what type of...
The enzyme responsible for enterohepatic cycling, Beta-glucuronidase,...
5-beta-pregnanediol is produced by changing the 3-keto group of...
Order the steps of enterohepatic cycling of estrogen, beginning in the...
Which of the following antiestrogens is NOT an aromatase inhibitor?
Which of the following describes histamine receptors?
Loratadine and Fexofenadine may have potentially life-threatening...
Estradiol enhances protein synthesis by altering the rate of...
Omalizumab causes which of the following?
Which of the following substituents (numbered) is CORRECTLY matched...
Synthetic glucocorticoids are slowly but completely absorbed orally.
Which of the following is a symptom of aldosteronism?
The FcE receptor is irreversibly bound to IgE on the surfaces of mast...
Steroids act by binding intracellular receptors; the steroid-receptor...
Another name for the enzyme Estrogen 2/4-hydroxylase is
Progesterone is converted to 6-alpha-hydroxyprogesterone by the...
This compound is hydrolyzed to a 17-beta ketol by which of the...
Which of the following are effects of Spironolactone?
Levocetirizine is an oxidation metabolite of Hydroxyzine. Which of the...
Mast cell stabilizers such as Cromolyn prevent the cytoskeletons of...
Which of the following are structural features of progestins, which...
Glucocorticoids and mineralocorticoids exhibit equal affinity for...
Of the following drugs, 3 are glucocorticoid synthesis inhibitors and...
Select all that apply. Symptoms of allergy include which of the...
The alkylamine Acrivastine is mildly more sedative than other second...
Which of the following is NOT a mineralocorticoid antagonist?
Adrenocorticosteroids are hormones derived from cholesterol and...
Which of the following is TRUE of inverse agonists such as...
Which class of antihistamines are the least sedating among first...
Select the ones you like
Which of the following is TRUE
Which of following is an adverse effect of the first generation...
Select all that apply. Which of the following are differences between...
Which of the following statements is FALSE regarding histamine?
Which of the following is FALSE of the molecule shown here?
Are you going to read Dr. S's research paper in sharepoint?
Select all that apply. Which of the following are effects of...
Which of the following classes of drugs are estrogen antagonists?
17-allpha hydroxylase catalyzes the conversion of cholesterol to...
Identify this drug.
The enzyme Aromatase can produce Estrone from which of the following...
Select all that apply. Which of the following may be long-term effects...
Which of the following are symptoms of chronic adrenocorticoid...
Which of the following are effects of glucocorticoids on the body?