Pmc 1 Exam 3

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  • NBME
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1. Match the receptor type to the effects observed when the receptor is BLOCKED

Explanation

(McCune Antihistamines)

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About This Quiz
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Androgens & Estrogens (Cox & Sumanasekera), Adrenocorticosteroids (Cox & Sumanasekera) and Antihistamines (Cox & McCune)

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2. Order the hormones in the synthesis of estradiol.

Explanation

Dr. S

Submit
3. Match the first generation antihistamine to its classification.

Explanation

(McCune antihistamines)

Submit
4. Isomers that exist in equilibrium and are readily interconverted by migration of a Hydrogen atom within the molecule are known as which of the following?

Explanation

(Cox Antihistamines)

Submit
5. How much cortisol is secreted by the body under stress compared to normal function?

Explanation

(Adrenocorticosteroids 1 Dr. S)

Submit
6. Match the disease or condition to its treatment.

Explanation

(Adrenocorticosteroids 2 Dr. S)

Submit
7. Match the following structural features to the adrenocorticoids they describe.

Explanation

cox adrenocorticoids 1

Submit
8. Match the hydrocortisone ester to its route of administration.

Explanation

cox adrenocorticoids 1

Submit
9. Match the second generation antihistamine to its classification.

Explanation

(McCune antihistamines)

Submit
10. Match the drug to its classification/mechanism.

Explanation

Dr. S

Submit
11. Match the glucocorticoid synthesis inhibitor with its mechanism of action.

Explanation

(Adrenocorticosteroids 2 Dr. S)

Submit
12. Match the receptor binding type to its level of intrinsic activity at the receptor.

Explanation

(Cox Antihistamines)

Submit
13. Match the type of steroid hormone to its structural features.

Explanation

Cox Androgens

Submit
14. Match the histamine receptor subtype to its location.

Explanation

H1 in smooth muscle, CNS and endothelia
H2 in parietal, cardiac, CNS, smooth and bronchial
H3 in CNS and PNS
H4 in WBC and RBC
(McCune Antihistamines)

Submit
15. Testosterone exhibits poor bioavailability due to extensive 1st pass metabolism.

Explanation

Cox androgens

Submit
16. Finasteride and Dutasteride act by which of the following mechanisms?

Explanation

they are 5aR inhibitors (cox androgens)

Submit
17. Suicide inhibition is another name for which type of binding, exhibited by steroid binding to aromatase?

Explanation

Irreversible binding of steroids to aromatase is known as suicide inhibition (cox estrogens)

Submit
18. Select two answers. Glucocorticoids mainly enhances which TWO of the following processes?

Explanation

they also regulate glycogen synthesis, but mainly gluconeogensis and glycogenolysis (Adrenocorticosteroids 1 Dr. S)

Submit
19. The drug-drug interaction between antibiotics and estrogens is due to the lack of Beta-glucuronidase that occurs after antibiotics kill intestinal bacteria. Estrogen levels decrease because estrogen can no longer undergo enterohepatic cycling.

Explanation

cox estrogens

Submit
20. The purpose of the addition of the 17-alpha alkyne group to this estrogen molecule is to

Explanation

this is Ethinyl Estradiol. the 17a-alkyne group increases oral bioavailability by preventing oxidation of C17 to a ketone (cox estrogens)

Submit
21. The steroid molecule shown here is transformed by which of the following enzymes?

Explanation

This steroid has an ester at C17, so it is transformed by esterases into a COOH and alcohol (Cox androgens)

Submit
22. Esterases metabolize lipophilic esters found at C17 on steroid molecules. Where in the body can these enzymes be found?

Explanation

esterases are found in nearly all tissues (cox androgens)

Submit
23. The antiandrogens Bicalutamide, Flutamide and Nilutamide act by blocking the effects of testosterone and DHT on androgen receptors in the treatment of advanced prostate cancer.

Explanation

Cox androgens

Submit
24. Promethazine has antiemetic effects and can be used in combination to reduce congestion.

Explanation

(McCune antihistamines)

Submit
25. What type of reaction is shown here?

Explanation

This is the oxidation of estradiol into estrione. Oxidation because it gains a bond to oxygen (cox estrogens)

Submit
26. Cortisol is mainly metabolized by which of the following organs?

Explanation

mainly in the liver, some in the kidney (Adrenocorticosteroids 1 Dr. S)

Submit
27. Which of the following is NOT a symptom of Addison's Disease?

Explanation

Addison's causes HYPOtension (Adrenocorticosteroids 2 Dr. S)

Submit
28. The 2nd generation piperadine antihistamine Terfenadine was removed from the market due to which of the following adverse effects?

Explanation

(McCune antihistamines)

Submit
29. Another name for leukotrienes is slow reacting substance of anaphylaxis. Leukotrienes have the same effects as histamine, but are more potent.

Explanation

(McCune antihistamines)

Submit
30. Zileuton inhibits which of the following enzymes?

Explanation

5-lipoxygenase converts arachadonic acid to LT's and Zileuton blocks it to reduce LT's (McCune antihistamines)

Submit
31. Selective Estrogen Receptor Modulators, or SERMs, act as agonists for estrogen in bone tissue (not marrow) and antagonists in breast tissue.

Explanation

SERMs are agonists in some tissues and antagonists in others (cox estrogens)

Submit
32. The enzyme which catalyzes the Phase 2 reaction of estradiol shown here is which of the following?

Explanation

Sulfotransferase conjugates a sulfate group in Phase 2 to make the molecule more polar so it can be removed from circulation by the kidneys (cox estrogens)

Submit
33. The reaction shown here occurs in Phase ___ and is catalyzed by the enzyme ______.

Explanation

this reaction is the glucuronide conjugation of estradiol by UGT in phase 2 (cox estrogens)

Submit
34. Fexofenadine is a non-cardiotoxic metabolite of Terfenadine. Fexofenadine has increased selectivity for H1 receptors compared to first generation antihistamines.

Explanation

(McCune antihistamines)

Submit
35. Dutasteride blocks the conversion of Testosterone to which of the following?

Explanation

Dr. S

Submit
36. The interconversion shown here is an example of which of the following?

Explanation

(Cox Antihistamines)

Submit
37. Which of the following is NOT an adverse effect of Ipratropium, an anticholinergic that can treat COPD and rhinorrhea due to its drying effects?

Explanation

(McCune antihistamines)

Submit
38. Codeine and morphine displace mast cell granules.

Explanation

this was bolded for some reason (McCune Antihistamines)

Submit
39. Spironolactone reverses the effects of aldosteronism and acts as a diuretic at the renal collecting tubules.

Explanation

(Adrenocorticosteroids 2 Dr. S)

Submit
40. Steroids bind receptors ____

Explanation

Steroids bind receptors intracellularly because they are lipid-soluble molecules that can easily pass through the cell membrane. Once inside the cell, steroids bind to specific intracellular receptors located in the cytoplasm or nucleus. This binding activates the receptor and initiates a series of cellular responses, including changes in gene expression. Unlike other signaling molecules that bind receptors on the cell membrane, steroids directly affect gene transcription and protein synthesis within the cell.

Submit
41. Match the hormone to the part of the adrenal gland that secretes it.

Explanation

estrogens/androgens Dr. S

Submit
42. The anticholinergic effects of antihistamines and other drugs are determined by the presence of two rings connected by a single intermediate link, an amino group and a short carbon chain between the rings and amino. Which of the following drugs does NOT have anticholinergic properties?

Explanation

all examples are shown in the slides (Cox Antihistamines)

Submit
43. The follicular phase of menstruation involves the conversion of pregnenolone to DHEA. The luteal phase involves the conversion of pregnenolone to which of the following?

Explanation

Luteal: pregnenolone to progesterone via 3B-dehydrogenase (S estrogens/androgens)

Submit
44. 5-alpha Reductase inhibitors, such as Dutasteride, are irreversible modifiers.

Explanation

5aRI's are irreversible (cox androgens)

Submit
45. Which feature of the molecule shown here is very rarely found in drug molecules today?

Explanation

Cox androgens

Submit
46. The structure shown here is produced by metabolism of Estrogen by Estrogen 2-hydroxylase enzyme. This molecule is further metabolized by which of the following enzymes?

Explanation

recognize that this product is now a catechol, which can be metabolized by COMT (catechol O-methyltransferase) (cox estrogens)

Submit
47. The most potent endogenous glucocorticoid is _____ while the most potent endogenous mineralocorticoid is _____.

Explanation

cox adrenocorticoids 1

Submit
48. Steroids are transported in the blood via transport proteins. Which of the following is NOT a transport protein for steroids?

Explanation

cox adrenocorticoids 1

Submit
49. Which of the following enzymes catalyzes the reaction shown here?

Explanation

cox adrenocorticoids 1

Submit
50. A substituent attached to the 10 Carbon on the steroid nucleus shown here would have what numbering?

Explanation

19 is attached to 10, 18 is attached to 13 (Cox Androgens)

Submit
51. Which of the following are Phase 2 reactions undergone by Estrogens?

Explanation

cox estrogens

Submit
52. 11-deoxycorticosterone is converted to Aldosterone in the Zona Glomerulosa via which of the following enzymes?

Explanation

Dr. S

Submit
53. The enzyme Aromatase produces 17b-estradiol from which of the following androgens?

Explanation

Dr. S

Submit
54. 90% of Cortisol in the body can be found where?

Explanation

cortisol is 90% bound to CBG; the rest is free. cortisol bound to albumin is considered free because it is loosely bound (Adrenocorticosteroids 1 Dr. S)

Submit
55. Which of the following enzymes is responsible for enterohepatic cycling?

Explanation

b-glucuronidase hydrolyzes estradil glucuronide back into estradiol so it can be cycled again (cox estrogens)

Submit
56. First generation molecules, like the diphenhydramine shown here, contain two aromatic groups linked through a short chain to a tertiary aliphatic amine. What classification of antihistamine is diphenhydramine?

Explanation

(Cox Antihistamines)

Submit
57. Deoxycorticosterone (DOC) is a precursor to aldosterone. Adrenal hyperplasia and carcinomas have what effect of DOC secretion?

Explanation

(Adrenocorticosteroids 2 Dr. S)

Submit
58. Why is the nitro group found in antiandrogens such as Nilutamide and Flutamide so unusual in modern drugs?

Explanation

Nitro groups are rarely used because they are highly hepatotoxic upon conversion to free radicals (cox androgens)

Submit
59. SERMs, such as Clomifene and Tamoxifen, act by which of the following mechanisms?

Explanation

cox estrogens

Submit
60. Progestins reduce the risk of cancer from estrogen therapy and decrease water retention by competing with aldosterone.

Explanation

Dr. S

Submit
61. Bioisosteres are chemical groups with similar physical and chemical properties in the body. Which of the following groups, shown in the picture, is a bioisostere for carboxylic acid and exhibits better penetration and bioavailability than carboxylic acid?

Explanation

(Cox Antihistamines)

Submit
62. Synthesis of histamine from histidine is which type of reaction?

Explanation

(Cox Antihistamines)

Submit
63. A 17-Beta Ketol group, which may or may not be esterified, is a MUST for which type of activity?

Explanation

cox adrenocorticoids 1

Submit
64. Histamine promotes wakefulness

Explanation

(McCune Antihistamines)

Submit
65. One example of a drug-drug interaction involving competition for steroid transport proteins is that between oral contraceptives and prednisolone.

Explanation

cox adrenocorticoids 1

Submit
66. The function of the enzyme Aromatase is to de-aromatize the A ring of androgen molecules.

Explanation

Aromatase aromatizes the A ring of androgens to produce estrogens (cox estrogens)

Submit
67. Cortisone is a prodrug of Hydrocortisone. The conversion of cortisone to hydrocortisone requires converting the 11-keto group to an 11-OH. This conversion is which type of reaction?

Explanation

converting a ketone to an alcohol loses an O bond, so it is a reduction (cox adrenocorticoids 1)

Submit
68. Estrogens have an aromatic A ring, 18 Carbons and a 3-OH group. Which of the following is the most potent estrogen?

Explanation

Estradiol is the most potent estrogen. Estrone is the most abundant estrogen. Other structures are Estriol and Progesterone (Cox estrogens)

Submit
69. People with parasitic diseases are more likely to develop allergies due to non-specific (allergen) IgE competing with parasite-specific IgE for binding to mast cells.

Explanation

they are LESS likely (McCune Antihistamines)

Submit
70. The purpose of esterification of steroid molecules with long carbon chains at C17 is to

Explanation

long chains are more lipophilic and thus harder to break down in the blood, extending the half life (Cox androgens)

Submit
71. 5-beta-pregnanediol is produced by changing the 3-keto group of progesterone to a 3-OH and saturating the double bond at the 4 position. This reaction is a(n)

Explanation

Changing the ketone to an alcohol loses a bond to O, so this is a reduction (cox estrogens)

Submit
72. The rightward reaction shown in this pictures is what type of reaction?

Explanation

the rightward reaction is the oxidation of estradiol into estrone. oxidation because it gains a bond to oxygen (cox estrogens)

Submit
73. The enzyme responsible for enterohepatic cycling, Beta-glucuronidase, can be found where?

Explanation

the enzyme is found in bacteria in the large intestine (cox estrogens)

Submit
74. Which of the following describes histamine receptors?

Explanation

(McCune Antihistamines)

Submit
75. Order the steps of enterohepatic cycling of estrogen, beginning in the liver.

Explanation

cox estrogens

Submit
76. Loratadine and Fexofenadine may have potentially life-threatening drug-drug interactions with CYP3A4 inhibitors such as macrolides and SSRI's.

Explanation

Loratadine and Fexofenadine have no DDI's. The CYP3A4 interactions were a problem with terfenadine (McCune antihistamines)

Submit
77. Which of the following antiestrogens is NOT an aromatase inhibitor?

Explanation

Clomifene is a triphenylethylene SERM (cox estrogens)

Submit
78. Estradiol enhances protein synthesis by altering the rate of transcription. Which of the following are functions of estradiol in the body?

Explanation

estrogen increases protein production and blood coagulation Dr. S

Submit
79. Omalizumab causes which of the following?

Explanation

Omalizumab decreases free IgE and decreases FcE receptor to block FcER binding sites on IgE (McCune antihistamines)

Submit
80. Which of the following substituents (numbered) is CORRECTLY matched with its designation as alpha or beta?

Explanation

alpha: hydrogens at 5, 9 and 14
beta: hydrogen at 8, methyls at

Submit
81. Synthetic glucocorticoids are slowly but completely absorbed orally.

Explanation

they are rapidly and completely absorbed PO (Adrenocorticosteroids 1 Dr. S)

Submit
82. Which of the following is a symptom of aldosteronism?

Explanation

Hyperpigmentation is caused by Addison's. Aldosteronism causes hypokalemia, alkalosis and hypernatremia (Adrenocorticosteroids 2 Dr. S)

Submit
83. The FcE receptor is irreversibly bound to IgE on the surfaces of mast cells and basophils

Explanation

(McCune antihistamines)

Submit
84. Progesterone is converted to 6-alpha-hydroxyprogesterone by the addition of a hydroxy group at the 6 position. This reaction is a(n)

Explanation

adding a bond to an O is an oxidation (cox estrogens)

Submit
85. Another name for the enzyme Estrogen 2/4-hydroxylase is

Explanation

cox estrogens

Submit
86. Steroids act by binding intracellular receptors; the steroid-receptor complex then enters the nucleus and changes levels of proteins by altering the rate of DNA replication.

Explanation

alters the rate of transcription and thus translation (Cox androgens)

Submit
87. This compound is hydrolyzed to a 17-beta ketol by which of the following enzymes?

Explanation

the water-soluble phosphate salt in the molecule is hydrolyzed by a phosphatase (cox adrenocorticoids 1)

Submit
88. Levocetirizine is an oxidation metabolite of Hydroxyzine. Which of the following is NOT true of levocetirizine?

Explanation

Levocetirizine and cetirizine have long durations of action (McCune antihistamines)

Submit
89. Mast cell stabilizers such as Cromolyn prevent the cytoskeletons of mast cells from collapsing by inhibiting which ion channels?

Explanation

(McCune antihistamines)

Submit
90. Which of the following are effects of Spironolactone?

Explanation

Aldosteronism causes hypernatremia, hypokalemia and metabolic alkalosis. Since Spironolactone reverses the effects of aldosteronism, Spironolactone causes hyperkalemia and metabolic acidosis. (Adrenocorticosteroids 2 Dr. S)

Submit
91. Which of the following are structural features of progestins, which promote gestation and relax the uterus?

Explanation

aromatic A are found in estrogens only (cox estrogens)

Submit
92. Glucocorticoids and mineralocorticoids exhibit equal affinity for mineralocorticoid receptors.

Explanation

(Adrenocorticosteroids 2 Dr. S)

Submit
93. Of the following drugs, 3 are glucocorticoid synthesis inhibitors and 1 is a glucocorticoid receptor antagonist. Select the glucocorticoid receptor antagonist.

Explanation

Mifepristone is the antagonist used to treat Cushing's. (Adrenocorticosteroids 2 Dr. S)

Submit
94. The alkylamine Acrivastine is mildly more sedative than other second generation antihistamines.

Explanation

(McCune antihistamines)

Submit
95. Select all that apply. Symptoms of allergy include which of the following?

Explanation

(McCune Antihistamines)

Submit
96. Which of the following is NOT a mineralocorticoid antagonist?

Explanation

Fludrocortisone is a mineralocorticoid and is one of the most commonly prescribed salt-retaining agents. It has both mineralocorticoid and glucocorticoid activity (Adrenocorticosteroids 2 Dr. S)

Submit
97. Adrenocorticosteroids are hormones derived from cholesterol and produced by the adrenal medulla in response to ACTH

Explanation

they are produced in the adrenal cortex. the medulla secretes catecholamines (Adrenocorticosteroids 1 Dr. S)

Submit
98. Which class of antihistamines are the least sedating among first generation?

Explanation

(McCune antihistamines)

Submit
99. Which of the following is TRUE of inverse agonists such as antihistamines?

Explanation

Inverse agonists bind a receptor and produce the opposite effect of an agonist. Their action is due to constitutive activity, in which the receptor supposedly opens and closes rapidly and is sometimes active and sometimes inactive. (Cox Antihistamines)

Submit
100. Select the ones you like

Explanation

The given question asks the test-taker to select the options they like. The correct answer is Option1, indicating that the test-taker likes Option1.

Submit
101. Which of the following is TRUE

Explanation

sedative and anticholinergic effects: diphen/prometh > bromph/chlor (McCune antihistamines)

Submit
102. Which of following is an adverse effect of the first generation piperadine antihistamine Cyproheptadine?

Explanation

awkward (McCune antihistamines)

Submit
103. Select all that apply. Which of the following are differences between second and first generation antihistamines?

Explanation

2nd gen are more selective of H1, don't cross the BBB and are less selective of Ser/alpha/musc receptors (McCune antihistamines)

Submit
104. Which of the following is FALSE of the molecule shown here?

Explanation

Cetirizine is non-sedating because the zwitterion is to polar to cross the BBB (Cox Antihistamines)

Submit
105. Which of the following statements is FALSE regarding histamine?

Explanation

Histamine is made from Histidine (Cox Antihistamines)

Submit
106. Select all that apply. Which of the following are effects of leukotriene receptor blockers such as Montelukast?

Explanation

(McCune antihistamines)

Submit
107. Are you going to read Dr. S's research paper in sharepoint?

Explanation

The answer "Nah" suggests that the person is not interested in reading Dr. S's research paper in SharePoint. This informal response indicates a lack of enthusiasm or willingness to engage with the research material.

Submit
108. Which of the following classes of drugs are estrogen antagonists?

Explanation

cox estrogens

Submit
109. 17-allpha hydroxylase catalyzes the conversion of cholesterol to glucocorticoids. Another name for this enzyme is

Explanation

(Adrenocorticosteroids 1 Dr. S)

Submit
110. Identify this drug.

Explanation

cox estrogens

Submit
111. The enzyme Aromatase can produce Estrone from which of the following androgens?

Explanation

Aromatase converts androstenedione to estrone and converts testosterone to estradiol. Other choices are testosterone, ethinyl estradiol and DHT (cox estrogens)

Submit
112. Select all that apply. Which of the following may be long-term effects of glucocorticoid use?

Explanation

glucocorticoids lower thyroid hormone and suppress growth long-term (Adrenocorticosteroids 1 Dr. S)

Submit
113. Which of the following are symptoms of chronic adrenocorticoid toxicity?

Explanation

others are short term (Adrenocorticosteroids 2 Dr. S)

Submit
114. Which of the following are effects of glucocorticoids on the body?

Explanation

(Adrenocorticosteroids 1 Dr. S)

Submit
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Match the receptor type to the effects observed when the receptor is...
Order the hormones in the synthesis of estradiol.
Match the first generation antihistamine to its classification.
Isomers that exist in equilibrium and are readily interconverted by...
How much cortisol is secreted by the body under stress compared to...
Match the disease or condition to its treatment.
Match the following structural features to the adrenocorticoids they...
Match the hydrocortisone ester to its route of administration.
Match the second generation antihistamine to its classification.
Match the drug to its classification/mechanism.
Match the glucocorticoid synthesis inhibitor with its mechanism of...
Match the receptor binding type to its level of intrinsic activity at...
Match the type of steroid hormone to its structural features.
Match the histamine receptor subtype to its location.
Testosterone exhibits poor bioavailability due to extensive 1st pass...
Finasteride and Dutasteride act by which of the following mechanisms?
Suicide inhibition is another name for which type of binding,...
Select two answers. Glucocorticoids mainly enhances which TWO of the...
The drug-drug interaction between antibiotics and estrogens is due to...
The purpose of the addition of the 17-alpha alkyne group to this...
The steroid molecule shown here is transformed by which of the...
Esterases metabolize lipophilic esters found at C17 on steroid...
The antiandrogens Bicalutamide, Flutamide and Nilutamide act by...
Promethazine has antiemetic effects and can be used in combination to...
What type of reaction is shown here?
Cortisol is mainly metabolized by which of the following organs?
Which of the following is NOT a symptom of Addison's Disease?
The 2nd generation piperadine antihistamine Terfenadine was removed...
Another name for leukotrienes is slow reacting substance of...
Zileuton inhibits which of the following enzymes?
Selective Estrogen Receptor Modulators, or SERMs, act as agonists for...
The enzyme which catalyzes the Phase 2 reaction of estradiol shown...
The reaction shown here occurs in Phase ___ and is catalyzed by the...
Fexofenadine is a non-cardiotoxic metabolite of Terfenadine....
Dutasteride blocks the conversion of Testosterone to which of the...
The interconversion shown here is an example of which of the...
Which of the following is NOT an adverse effect of Ipratropium, an...
Codeine and morphine displace mast cell granules.
Spironolactone reverses the effects of aldosteronism and acts as a...
Steroids bind receptors ____
Match the hormone to the part of the adrenal gland that secretes it.
The anticholinergic effects of antihistamines and other drugs are...
The follicular phase of menstruation involves the conversion of...
5-alpha Reductase inhibitors, such as Dutasteride, are irreversible...
Which feature of the molecule shown here is very rarely found in drug...
The structure shown here is produced by metabolism of Estrogen by...
The most potent endogenous glucocorticoid is _____ while the most...
Steroids are transported in the blood via transport proteins. Which of...
Which of the following enzymes catalyzes the reaction shown here?
A substituent attached to the 10 Carbon on the steroid nucleus shown...
Which of the following are Phase 2 reactions undergone by Estrogens?
11-deoxycorticosterone is converted to Aldosterone in the Zona...
The enzyme Aromatase produces 17b-estradiol from which of the...
90% of Cortisol in the body can be found where?
Which of the following enzymes is responsible for enterohepatic...
First generation molecules, like the diphenhydramine shown here,...
Deoxycorticosterone (DOC) is a precursor to aldosterone. Adrenal...
Why is the nitro group found in antiandrogens such as Nilutamide and...
SERMs, such as Clomifene and Tamoxifen, act by which of the following...
Progestins reduce the risk of cancer from estrogen therapy and...
Bioisosteres are chemical groups with similar physical and chemical...
Synthesis of histamine from histidine is which type of reaction?
A 17-Beta Ketol group, which may or may not be esterified, is a MUST...
Histamine promotes wakefulness
One example of a drug-drug interaction involving competition for...
The function of the enzyme Aromatase is to de-aromatize the A ring of...
Cortisone is a prodrug of Hydrocortisone. The conversion of cortisone...
Estrogens have an aromatic A ring, 18 Carbons and a 3-OH group. Which...
People with parasitic diseases are more likely to develop allergies...
The purpose of esterification of steroid molecules with long carbon...
5-beta-pregnanediol is produced by changing the 3-keto group of...
The rightward reaction shown in this pictures is what type of...
The enzyme responsible for enterohepatic cycling, Beta-glucuronidase,...
Which of the following describes histamine receptors?
Order the steps of enterohepatic cycling of estrogen, beginning in the...
Loratadine and Fexofenadine may have potentially life-threatening...
Which of the following antiestrogens is NOT an aromatase inhibitor?
Estradiol enhances protein synthesis by altering the rate of...
Omalizumab causes which of the following?
Which of the following substituents (numbered) is CORRECTLY matched...
Synthetic glucocorticoids are slowly but completely absorbed orally.
Which of the following is a symptom of aldosteronism?
The FcE receptor is irreversibly bound to IgE on the surfaces of mast...
Progesterone is converted to 6-alpha-hydroxyprogesterone by the...
Another name for the enzyme Estrogen 2/4-hydroxylase is
Steroids act by binding intracellular receptors; the steroid-receptor...
This compound is hydrolyzed to a 17-beta ketol by which of the...
Levocetirizine is an oxidation metabolite of Hydroxyzine. Which of the...
Mast cell stabilizers such as Cromolyn prevent the cytoskeletons of...
Which of the following are effects of Spironolactone?
Which of the following are structural features of progestins, which...
Glucocorticoids and mineralocorticoids exhibit equal affinity for...
Of the following drugs, 3 are glucocorticoid synthesis inhibitors and...
The alkylamine Acrivastine is mildly more sedative than other second...
Select all that apply. Symptoms of allergy include which of the...
Which of the following is NOT a mineralocorticoid antagonist?
Adrenocorticosteroids are hormones derived from cholesterol and...
Which class of antihistamines are the least sedating among first...
Which of the following is TRUE of inverse agonists such as...
Select the ones you like
Which of the following is TRUE
Which of following is an adverse effect of the first generation...
Select all that apply. Which of the following are differences between...
Which of the following is FALSE of the molecule shown here?
Which of the following statements is FALSE regarding histamine?
Select all that apply. Which of the following are effects of...
Are you going to read Dr. S's research paper in sharepoint?
Which of the following classes of drugs are estrogen antagonists?
17-allpha hydroxylase catalyzes the conversion of cholesterol to...
Identify this drug.
The enzyme Aromatase can produce Estrone from which of the following...
Select all that apply. Which of the following may be long-term effects...
Which of the following are symptoms of chronic adrenocorticoid...
Which of the following are effects of glucocorticoids on the body?
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