Basic Pharmacology Exam: Quiz!
(203).jpg "Basic Pharmacology Exam: Quiz!")
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- 1.Science of interaction between chemicals and living organisms.
- 2.Part of pharmacology which deals with absorption, biotransformation, distribution, and elimination of drugs is:
- 3.Movement of a drug from its site of administration into the blood.
- 4.Metabolism which occurs before the drug reaches systemic circulation is
- 5.Movement of a drug from the blood into various tissues of the body and back.
- 6.Chemical changes of drugs occurring in the liver.
- 7.Loss of a drug from the body is:
- 8.The relation between the total amount of drug in the body and concentration in plasma is:
- 9.Plasma volume cleared from a certain substance per unit of time is:
- 10.The time required for change of plasma level by half____
- 11.Percentage of the dose which reaches systemic circulation unchanged.
- 12.Part of pharmacology which deals with mechanism of action and effects of drugs on the body is
- 13.Changes caused by a drug occurring at the molecular and cellular levels.
- 14.Specialized cellular target macromolecule which receives the signal is
- 15.A substance which forms/transmits the signal (ligates to the specialized cellular macromolecule) is
- 16.Noxious and unintended response to a medicinal product.
- 17.The response is most rapid following the binding of a ligand to:
- A.
Intracellular receptors
- B.
Spare receptors
- C.
Ligand-gated ion channels
- D.
Receptors the underwent phosphorylation
- E.
G protein-coupled receptors
- F.
Enzyme-linked receptors
- G.
Receptors that underwent down-regulation
- H.
Option 8
- 18.The fraction of the administered dose that reaches systemic circulation unchanged is
- A.
Pharmacology
- B.
Elimination
- C.
Ligand
- D.
Biotransformation
- E.
Adverse reaction
- F.
Pre-systemic metabolism
- G.
Adverse event
- H.
Agonist
- I.
Volume of distribution
- J.
Distribution
- K.
Clearance
- L.
Half life
- M.
Bioavailability
- N.
Absorption
- O.
Option 15
- 19.Changes in gene expression occur following binding of a ligand to
- A.
Receptors that underwent phosphorylation
- B.
G protein-coupled receptors
- C.
Spare receptors
- D.
Ligand-gated ion channels
- E.
Intracellular receptors
- F.
Receptors that underwent down regulation
- G.
Enzyme- linked receptors
- 20.Insulin acts at the extracellular domain of membrane-spanning tyrosine kinase and causes its phosphorylation. afterward, tyrosine kinase activated intracellular enzymes responsible for glucose catabolism. to which family of receptors does tyrosine kinase belong?
- A.
Ligand-gated ion channels
- B.
Intracellular receptors
- C.
Enzyme linked receptors
- D.
G protein-coupled receptors
- E.
Spare receptors
- 21.What receptors have only hydrophobic ligands?
- A.
Ligand-gated ion channels
- B.
Intracellular receptors
- C.
Spare receptors
- D.
Enzyme linked receptors
- E.
G protein-coupled receptors
- 22.Gastric acid secretion is stimulated by acetylcholine, histamine, and gastrin, the membrane receptor-mediated binding of acetylcholine, histamine, or gastrin results in activation of adenylyl cyclase...
- A.
Ligand-gated ion channels
- B.
Gq
- C.
Enzyme-linked
- D.
Gs
- E.
Intracellular
- F.
Gi
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