Basic Pharmacology Exam: Quiz!

22 Questions | Total Attempts: 165

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Basic Pharmacology Exam: Quiz!

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Questions and Answers
  • 1. 
    Science of interaction between chemicals and living organisms.
  • 2. 
    Part of pharmacology which deals with absorption, biotransformation, distribution, and elimination of drugs is:
  • 3. 
    Movement of a drug from its site of administration into the blood.
  • 4. 
    Metabolism which occurs before the drug reaches systemic circulation is
  • 5. 
    Movement of a drug from the blood into various tissues of the body and back.
  • 6. 
    Chemical changes of drugs occurring in the liver.
  • 7. 
    Loss of a drug from the body is:
  • 8. 
    The relation between the total amount of drug in the body and concentration in plasma is:
  • 9. 
    Plasma volume cleared from a certain substance per unit of time is:
  • 10. 
    The time required for change of plasma level by half____
  • 11. 
     Percentage of the dose which reaches systemic circulation unchanged.
  • 12. 
    Part of pharmacology which deals with mechanism of action and effects of drugs on the body is
  • 13. 
    Changes caused by a drug occurring at the molecular and cellular levels.
  • 14. 
    Specialized cellular target macromolecule which receives the signal is
  • 15. 
    A substance which forms/transmits the signal (ligates to the specialized cellular macromolecule) is
  • 16. 
    Noxious and unintended response to a medicinal product.
  • 17. 
    The response is most rapid following the binding of a ligand to:
    • A. 

      Intracellular receptors 

    • B. 

      Spare receptors

    • C. 

      Ligand-gated ion channels 

    • D. 

      Receptors the underwent phosphorylation 

    • E. 

      G protein-coupled receptors

    • F. 

      Enzyme-linked receptors

    • G. 

      Receptors that underwent down-regulation 

    • H. 

      Option 8

  • 18. 
    The fraction of the administered dose that reaches systemic circulation unchanged is 
    • A. 

      Pharmacology 

    • B. 

      Elimination 

    • C. 

      Ligand

    • D. 

      Biotransformation 

    • E. 

      Adverse reaction 

    • F. 

      Pre-systemic metabolism 

    • G. 

      Adverse event 

    • H. 

      Agonist 

    • I. 

      Volume of distribution 

    • J. 

      Distribution 

    • K. 

      Clearance 

    • L. 

      Half life 

    • M. 

      Bioavailability 

    • N. 

      Absorption 

    • O. 

      Option 15

  • 19. 
    Changes in gene expression occur following binding of a ligand to 
    • A. 

      Receptors that underwent phosphorylation

    • B. 

      G protein-coupled receptors 

    • C. 

      Spare receptors

    • D. 

      Ligand-gated ion channels

    • E. 

      Intracellular receptors

    • F. 

      Receptors that underwent down regulation 

    • G. 

      Enzyme- linked receptors

  • 20. 
    Insulin acts at the extracellular domain of membrane-spanning tyrosine kinase and causes its phosphorylation. afterward, tyrosine kinase activated intracellular enzymes responsible for glucose catabolism. to which family of receptors does tyrosine kinase belong? 
    • A. 

      Ligand-gated ion channels 

    • B. 

      Intracellular receptors 

    • C. 

      Enzyme linked receptors

    • D. 

      G protein-coupled receptors 

    • E. 

      Spare receptors

  • 21. 
    What receptors have only hydrophobic ligands? 
    • A. 

      Ligand-gated ion channels 

    • B. 

      Intracellular receptors 

    • C. 

      Spare receptors 

    • D. 

      Enzyme linked receptors

    • E. 

      G protein-coupled receptors

  • 22. 
    Gastric acid secretion is stimulated by acetylcholine, histamine, and gastrin, the membrane receptor-mediated binding of acetylcholine, histamine, or gastrin results in activation of adenylyl cyclase...
    • A. 

      Ligand-gated ion channels 

    • B. 

      Gq 

    • C. 

      Enzyme-linked

    • D. 

      Gs 

    • E. 

      Intracellular

    • F. 

      Gi 

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