Basic Pharmacology Exam: Quiz!

22 Questions | By Barli550 | Updated: Mar 21, 2022 | Attempts: 1195

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1.

Science of interaction between chemicals and living organisms.
2.

Part of pharmacology which deals with absorption, biotransformation, distribution, and elimination of drugs is:
3.

Movement of a drug from its site of administration into the blood.
4.

Metabolism which occurs before the drug reaches systemic circulation is
5.

Movement of a drug from the blood into various tissues of the body and back.
6.

Chemical changes of drugs occurring in the liver.
7.

Loss of a drug from the body is:
8.

The relation between the total amount of drug in the body and concentration in plasma is:
9.

Plasma volume cleared from a certain substance per unit of time is:
10.

The time required for change of plasma level by half____
11.

Percentage of the dose which reaches systemic circulation unchanged.
12.

Part of pharmacology which deals with mechanism of action and effects of drugs on the body is
13.

Changes caused by a drug occurring at the molecular and cellular levels.
14.

Specialized cellular target macromolecule which receives the signal is
15.

A substance which forms/transmits the signal (ligates to the specialized cellular macromolecule) is
16.

Noxious and unintended response to a medicinal product.
17.

The response is most rapid following the binding of a ligand to:
- A.
  
  Intracellular receptors
- B.
  
  Spare receptors
- C.
  
  Ligand-gated ion channels
- D.
  
  Receptors the underwent phosphorylation
- E.
  
  G protein-coupled receptors
- F.
  
  Enzyme-linked receptors
- G.
  
  Receptors that underwent down-regulation
- H.
  
  Option 8
18.

The fraction of the administered dose that reaches systemic circulation unchanged is
- A.
  
  Pharmacology
- B.
  
  Elimination
- C.
  
  Ligand
- D.
  
  Biotransformation
- E.
  
  Adverse reaction
- F.
  
  Pre-systemic metabolism
- G.
  
  Adverse event
- H.
  
  Agonist
- I.
  
  Volume of distribution
- J.
  
  Distribution
- K.
  
  Clearance
- L.
  
  Half life
- M.
  
  Bioavailability
- N.
  
  Absorption
- O.
  
  Option 15
19.

Changes in gene expression occur following binding of a ligand to
- A.
  
  Receptors that underwent phosphorylation
- B.
  
  G protein-coupled receptors
- C.
  
  Spare receptors
- D.
  
  Ligand-gated ion channels
- E.
  
  Intracellular receptors
- F.
  
  Receptors that underwent down regulation
- G.
  
  Enzyme- linked receptors
20.

Insulin acts at the extracellular domain of membrane-spanning tyrosine kinase and causes its phosphorylation. afterward, tyrosine kinase activated intracellular enzymes responsible for glucose catabolism. to which family of receptors does tyrosine kinase belong?
- A.
  
  Ligand-gated ion channels
- B.
  
  Intracellular receptors
- C.
  
  Enzyme linked receptors
- D.
  
  G protein-coupled receptors
- E.
  
  Spare receptors
21.

What receptors have only hydrophobic ligands?
- A.
  
  Ligand-gated ion channels
- B.
  
  Intracellular receptors
- C.
  
  Spare receptors
- D.
  
  Enzyme linked receptors
- E.
  
  G protein-coupled receptors
22.

Gastric acid secretion is stimulated by acetylcholine, histamine, and gastrin, the membrane receptor-mediated binding of acetylcholine, histamine, or gastrin results in activation of adenylyl cyclase...
- A.
  
  Ligand-gated ion channels
- B.
  
  Gq
- C.
  
  Enzyme-linked
- D.
  
  Gs
- E.
  
  Intracellular
- F.
  
  Gi