Quiz On K6 & K7 Pharmacology Sem 2 Session 2018-2019 (Nb 2264)
- 1.The following statement(s) is/are TRUE with regards to autonomic nervous system:
- A.
Parasympathetic preganglionic fibres are shorter than sympathetic preganglionic fibres.
- B.
The receptors at postganglionic neuron at the sweat gland are muscarinic.
- C.
All preganglionic autonomic neurons secrete acetylcholine.
- D.
The receptors at all parasympathetic postganglionic neurons are nicotinic.
- E.
Adrenal medulla is innervated by the parasympathetic nervous system.
- 2.The tissues in which the sympathetic nervous system dominate include the
- A.
Ciliary muscle of the eye.
- B.
Vagus nerve of the heart.
- C.
Sphincter muscle of the iris.
- D.
Renin-secreting cells of the kidney.
- E.
The ejaculatory muscle of the genital organ.
- 3.The following statement(s) is/are TRUE with regards to cholinergic transmission:
- A.
The vesicular ACh-H+ antiporter is a target for vesamicol.
- B.
Botulinum toxin inhibits the fusion of vesicles to presynaptic membrane.
- C.
Nicotinic receptors belong to the G-protein-coupled receptor superfamily.
- D.
Acetylcholine in the synaptic cleft is degraded by choline acetyltransferase.
- E.
Hemicholinium inhibits the synthesis of acetylcholine in the nerve terminal.
- 4.The following statement(s) is/are TRUE with regards the actions of noradrenaline:
- A.
It binds to receptors located on autonomic ganglia.
- B.
Binding to α2-receptors will inhibit noradrenaline release from the nerve ending.
- C.
Its action is mainly terminated by Uptake 1 mechanism.
- D.
Reserpine may depletes its storage in the vesicles.
- E.
Binding to β2-receptors causes vasoconstriction.
- 5.The adrenoceptor subtype(s) which cause(s) liver glycogenolysis and gluconeogenesis is/are
- A.
α1 (Gq).
- B.
α1 (Gq).
- C.
β1 (Gs).
- D.
β2 (Gs).
- E.
β3 (Gs).
- 6.The following statement(s) is/are TRUE with regards to adrenergic transmission :
- A.
An essential amino acid involved in the biosynthesis of catecholamines is tyrosine.
- B.
Noradrenaline is synthesized by DOPA-decarboxylase in the synaptic vesicle.
- C.
Cocaine interferes with the reuptake of noradrenaline into the nerve terminal.
- D.
Noradrenaline in the cytosol is degraded by catechol-O-methyl transferase
- E.
Disulfiram inhibits dopamine-β-hydroxylase leading to increased brain dopamine levels.
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