Year 1 Pharmacokinetic (Basic)

Pramacokinetic processes - What does ADME stand for?

What are the basic pharmacokinetic parameters?

Pharmacokinetics: What the body does to the drug

Name one of the elimination terms.

What are the considerations for ABSORPTION

Name one route of administration.

Name one PARENTERAL route of administration. *parenteral = located outside the alimentary tract

Name one ENTERAL route of administration. *enteral = intestines-related

Oral administration is used mainly for systemic effect. However, is occasionally used for local effect such as diarrhoea and constipation.

First-pass Effect a) consume drugs b) drugs dissolve c) drugs in soltion enter gastro intestinal tract d) liver with enzymes biotransform/metabolise compounds + drugs (first pass) e) drugs absorbed and enter bloodstream f) drugs go through systemic circulation g) liver with enzymes biotransform/metabolise compounds + drugs (2nd, 3rd, 4th etc pass)