Pharmacology Pharmacokinetics Introduction Quiz!

20 Questions | By Pharmdnate | Updated: Mar 22, 2022 | Attempts: 38555

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Pharmacology Pharmacokinetics Introduction Quiz! - Quiz

Different drugs have different ways in which they enter the body and attack the base for an illness or diseases. The pharmacokinetic process is concerned with the absorption, distribution and elimination of drugs. In the Pharmacology class we got to learn more on pharmacokinetics and the test below is designed to see how much you understood. Give it a try!

Questions and Answers

1.

What describes the action of the body on the drug?
- A.
  
  Pharmacodynamics
- B.
  
  Pharmacokinetics
- C.
  
  Microbiology
- D.
  
  Physiology
- E.
  
  All of the above
2.

What describes the action of a drug on the body?
- A.
  
  Pharmacodynamics
- B.
  
  Pharmacokinetics
- C.
  
  Microbiology
- D.
  
  Physiology
- E.
  
  None of the above
3.

What is the entry of drugs into the plasma?
- A.
  
  Absorption
- B.
  
  Distribution
- C.
  
  Elimination
- D.
  
  Metabolism
- E.
  
  All of the above
4.

CWhich of the following is a disadvantage of using oral drugs
- A.
  
  First pass effect
- B.
  
  Low bioavailability
- C.
  
  Overdose overcome by antidotes
- D.
  
  A and B
- E.
  
  B and C
5.

Which of the following is an advantage of sublingual administration?
- A.
  
  Rapid absorption
- B.
  
  Convenient
- C.
  
  Avoid harsh GI environment
- D.
  
  Avoid first pass-metabolism
- E.
  
  All off the above
6.

Which of the following routes have the highest bioavailability?
- A.
  
  Oral
- B.
  
  IM
- C.
  
  IV
- D.
  
  SC
- E.
  
  None of the above
7.

Which of the following is a disadvantage of IM administration?
- A.
  
  Larger volumes can be used
- B.
  
  Can affect lab tests
- C.
  
  Painful
- D.
  
  A and C
- E.
  
  B and C
8.

What is the fraction of unchanged drug reaching the systemic circulation?
- A.
  
  Elimination
- B.
  
  Bioavailability
- C.
  
  Metabolism
- D.
  
  Drug displacement
- E.
  
  Volume of distribution (Vd)
9.

Which of the following are well-perfused tissues?
- A.
  
  Brain
- B.
  
  Skelatal
- C.
  
  Bone
- D.
  
  Adipose
- E.
  
  None of the above
10.

Which of the following are poorly perfused tissues?
- A.
  
  Heart
- B.
  
  Brain
- C.
  
  Liver
- D.
  
  Kidneys
- E.
  
  None of the above
11.

Where are large fenestrations or slit junctions located?
- A.
  
  Bone
- B.
  
  Brain
- C.
  
  Skin
- D.
  
  Liver
- E.
  
  All of the above
12.

Where are tight junctions created by two adjoining cells located?
- A.
  
  Bone
- B.
  
  Brain
- C.
  
  Skin
- D.
  
  Liver
- E.
  
  All of the above
13.

What takes up a large amount of drug?
- A.
  
  Muscles
- B.
  
  Adipose
- C.
  
  Brain
- D.
  
  A and B
- E.
  
  A and C
14.

The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A.
  
  High
- B.
  
  Low
- C.
  
  Unchanged
- D.
  
  Cannot be determined
15.

The volume of distribution (Vd) for a drug highly bound in peripheral tissues would be?
- A.
  
  High
- B.
  
  Low
- C.
  
  Unchanged
- D.
  
  Cannot be determine
16.

Drugs bound to albumin are inactive.
- A.
  
  True
- B.
  
  False
17.

Binding of drugs to albumin is irreversible.
- A.
  
  True
- B.
  
  False
18.

Which of the following does albumin have the strongest affinity for?
- A.
  
  Amionic drugs
- B.
  
  Hydrophilic drugs
- C.
  
  Hydrophobic drugs
- D.
  
  A and B
- E.
  
  A and C
19.

A patient with an edema would have an increased volume of distribution (Vd) if?
- A.
  
  The patient was taking an anionic drug
- B.
  
  The patient was taking a hydrophobic drug
- C.
  
  The patient was taking a hydrophilic drug
- D.
  
  An edema always causes an increase in Vd
- E.
  
  An edema always causes an decrease in Vd
20.

Only free drugs can act on target sites and can be eliminated.
- A.
  
  True
- B.
  
  False