Pharmacology Pharmacokinetics Introduction
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Different drugs have different ways in which they enter the body and attack the base for an illness or diseases. The pharmacokinetic process is concerned with the absorption, distribution and elimination of drugs. In the Pharmacology class we got to learn more on pharmacokinetics and the test below is designed to see how much you understood. Give it a try!
- 1.
- A.
Pharmacodynamics
- B.
Pharmacokinetics
- C.
Microbiology
- D.
Physiology
- E.
All of the above
- 2.What describes the action of a drug on the body?
- A.
Pharmacodynamics
- B.
Pharmacokinetics
- C.
Microbiology
- D.
Physiology
- E.
None of the above
- 3.What is the entry of drugs into the plasma?
- A.
Absorption
- B.
Distribution
- C.
Elimination
- D.
Metabolism
- E.
All of the above
- 4.
- A.
First pass effect
- B.
Low bioavailability
- C.
Overdose overcome by antidotes
- D.
A and B
- E.
B and C
- 5.Which of the following is an advantage of sublingual administration?
- A.
Rapid absorption
- B.
Convenient
- C.
Avoid harsh GI environment
- D.
Avoid first pass-metabolism
- E.
All off the above
- 6.Which of the following routes have the highest bioavailability?
- A.
Oral
- B.
IM
- C.
IV
- D.
SC
- E.
None of the above
- 7.Which of the following is a disadvantage of IM administration?
- A.
Larger volumes can be used
- B.
Can affect lab tests
- C.
Painful
- D.
A and C
- E.
B and C
- 8.What is the fraction of unchanged drug reaching the systemic circulation?
- A.
Elimination
- B.
Bioavailability
- C.
Metabolism
- D.
Drug displacement
- E.
Volume of distribution (Vd)
- 9.Which of the following are well-perfused tissues?
- A.
Brain
- B.
Skelatal
- C.
Bone
- D.
Adipose
- E.
None of the above
- 10.Which of the following are poorly perfused tissues?
- A.
Heart
- B.
Brain
- C.
Liver
- D.
Kidneys
- E.
None of the above
- 11.Where are large fenestrations or slit junctions located?
- A.
Bone
- B.
Brain
- C.
Skin
- D.
Liver
- E.
All of the above
- 12.Where are tight junctions created by two adjoining cells located?
- A.
Bone
- B.
Brain
- C.
Skin
- D.
Liver
- E.
All of the above
- 13.What takes up a large amount of drug?
- A.
Muscles
- B.
Adipose
- C.
Brain
- D.
A and B
- E.
A and C
- 14.The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A.
High
- B.
Low
- C.
Unchanged
- D.
Cannot be determined
- 15.The volume of distribution (Vd) for a drug highly bound in peripheral tissues would be?
- A.
High
- B.
Low
- C.
Unchanged
- D.
Cannot be determine
- 16.Drugs bound to albumin are inactive.
- A.
True
- B.
False
- 17.Binding of drugs to albumin is irreversible.
- A.
True
- B.
False
- 18.Which of the following does albumin have the strongest affinity for?
- A.
Amionic drugs
- B.
Hydrophilic drugs
- C.
Hydrophobic drugs
- D.
A and B
- E.
A and C
- 19.
- A.
The patient was taking an anionic drug
- B.
The patient was taking a hydrophobic drug
- C.
The patient was taking a hydrophilic drug
- D.
An edema always causes an increase in Vd
- E.
An edema always causes an decrease in Vd
- 20.Only free drugs can act on target sites and can be eliminated.
- A.
True
- B.
False
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