Pharmacotherapy Exam 1 September 27: Lecture 1 - Pharmacokinetics, ETC

10 Questions | Total Attempts: 4568

Pharmacokinetics Quizzes & Trivia

Creighton University Nursing Pharmacotherapy exam 1 learning quiz. This quiz might NOT simulate any case/scenario exam questions. Rather, it is only meant to reinforce the basics and the details that exam scenario questions would be built on. So as not to discourage anyone from adding good questions, let's just say that as long as you are close in the "fill in the blanks" answers (you decide) count yourself right. Otherwise, the question creator will have to try to think of every possible way a quiz taker might type in a right answer, and that is too much to require of us.

Questions and Answers
  • 1. 
    Drug solubility to cross membranes: when the drug is in stomach acid, it will pass through the stomach walls best if it is an acidic drug, neutral drug, or alkaline drug? 
    • A. 


    • B. 


    • C. 


  • 2. 
    Most drugs cross cell membranes by which means of transport:
    • A. 


    • B. 

      Non-ionized passive diffusion

    • C. 

      Filtration through pores

    • D. 

      Ionized active diffusion

    • E. 

      Ionized passive diffusion

  • 3. 
    The definition of absorption tells us that the drug is absorbed when it reaches:
    • A. 

      The bloodstream

    • B. 

      The target organ

    • C. 

      The site of lipid, bone or other organ storage

  • 4. 
    An enteric-coated drug differs from a time-release form of the drug by which physical differences and which differences in purpose, given that both are taken orally?  (Freeform answer, so it can not really be gotten correct)
  • 5. 
    Levodopa is described as a drug that does not act by stimulation of a receptor.  Its action instead is that it is converted to what neurotransmitter?
  • 6. 
    The drug class of drug NOT stimulating receptors but rather by inhibiting ion channels to affect electrical properties of certain cells?
  • 7. 
    When therapeutic index is high, the margin of safety is:
    • A. 


    • B. 


  • 8. 
    LD50  is
    • A. 

      Dose amount that killed 50% of the people in development of the drug

    • B. 

      Dose that kills 50% of animals given the drug

    • C. 

      Dose needed to ensure the desired effect in at least half of the subjects

  • 9. 
    Efficacy vs Potency - Which term evaluates the dose required to reach ED50 and which term relates to the maximum response of a drug?
    • A. 

      Potency relates dose amount to ED50, efficacy relates to maximum response

    • B. 

      Efficacy relates dose amount to ED50, potency relates to maximum response

  • 10. 
    Given that a specific drug's maximum effect is reached prior to occupation of all available receptors, what risk is associated with stimulation of the "spare receptors"?
    • A. 


    • B. 

      Higher therapeutic index

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