Immunology Quiz- Introduction To Antigen Recognition

15 Questions

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Immunology Quizzes & Trivia

Questions and Answers
  • 1. 
    • A. 

      They are serum proteins that form protein cascades, each activated component activating the next to generate a physiologic response

    • B. 

      They can bind to bacteria, making holes in their membrane

    • C. 

      They attract phagocytes to both foreign material and self cells

    • D. 

      Binding of MBLs to a bacterial capsule triggers the complement cascade

    • E. 

      They help to eliminate immune complexes (antibody-antigen) and prevent them from damaging the body

  • 2. 
    Which of the following key components of the complement pathway can be activated by the lectin, classical, and alternative pathways?
    • A. 

      C1

    • B. 

      C3

    • C. 

      C5

    • D. 

      C7

    • E. 

      C9

  • 3. 
    Match the three types of molecules that recognize antigen with their description: Can create a soluble antigen receptor (antibody)
    • A. 

      B cell receptor (BCR)

    • B. 

      T cell receptor (TCR)

    • C. 

      Major histocompatibility complex (MHC)

  • 4. 
    Match the three types of molecules that recognize antigen with their description: Recognize antigens bound to MHC
    • A. 

      B cell receptor (BCR)

    • B. 

      T cell receptor (TCR)

    • C. 

      Major histocompatibility complex (MHC)

  • 5. 
    Match the three types of molecules that recognize antigen with their description: A cluster of genes that encode proteins
    • A. 

      B cell receptor (BCR)

    • B. 

      T cell receptor (TCR)

    • C. 

      Major histocompatibility complex (MHC)

  • 6. 
    The genes encoding which of the following can undergo hypermutation to create receptors that are an even better fit for foreign antigens?
    • A. 

      BCRs

    • B. 

      TCRs

    • C. 

      MHCs

    • D. 

      BCRs & TCRs

    • E. 

      BCRs, TCRs, & MHCs

  • 7. 
    Which of the following has an immunoglobulin fold?
    • A. 

      BCRs

    • B. 

      TCRs

    • C. 

      MHCs

    • D. 

      BCRs & TCRs

    • E. 

      BCRs, TCRs, & MHCs

  • 8. 
    The genes encoding which of the following are extensively polymorphic (have multiple alleles or forms of the same gene)?
    • A. 

      BCRs

    • B. 

      TCRs

    • C. 

      MHCs

    • D. 

      BCRs & TCRs

    • E. 

      BCRs, TCRs, & MHCs

  • 9. 
    What types of cell is class I MHC found on?
    • A. 

      B cells

    • B. 

      Macrophages

    • C. 

      Dendritic cells

    • D. 

      Essentially all cells

    • E. 

      Mainly on A, B, & C

  • 10. 
    What types of cell is class II MHC found on?
    • A. 

      B cells

    • B. 

      Macrophages

    • C. 

      Dendritic cells

    • D. 

      Essentially all cells

    • E. 

      Mainly on A, B, & C

  • 11. 
    What is the function of major histocompatibility complex (MHC) molecules?
    • A. 

      Present sugars to T cells

    • B. 

      Present peptides to T cells

    • C. 

      Create holes in the membranes of bacteria

    • D. 

      Lyse foreign antigens

    • E. 

      Phagocytize foreign antigens

  • 12. 
    Unlike B cell receptors (BCRs), T cell receptors (TCRs) can only recognize foreign antigen if it is presented as a complex with a MHC molecule.
    • A. 

      True

    • B. 

      False

  • 13. 
    If the structure of an individuals MHC molecules makes it impossible for them to recognize and bind any peptide antigen from a given virus, that individual will still be able to activate a T cell response to cells infected with that virus.
    • A. 

      True

    • B. 

      False

  • 14. 
     Which of the following is NOT true about MHC molecules but true about B and T cells?
    • A. 

      The genes that encode molecules are the most variable genes we know of in the human genome (polygenic)

    • B. 

      They are extensively polymorphic (existence of multiple alleles or forms of the same gene)

    • C. 

      Every cell in each individual expresses the same set of molecules

    • D. 

      ) Every cell expresses a different molecule created from multiple gene segments that undergo somatic rearrangement

    • E. 

      Their diversity exists in the population as a whole, not in the individual

  • 15. 
    Given that an individual’s parents have completely different HLA genes, that individual will have about____ different class I and II MHC molecules on the surface of certain of their lymphoid cells.
    • A. 

      3

    • B. 

      6

    • C. 

      9

    • D. 

      12

    • E. 

      15