Immunology Quiz- Introduction To Antigen Recognition

15 Questions | By Smb6 | Updated: Dec 2, 2022 | Attempts: 1312

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Immunology Quiz- Introduction To Antigen Recognition - Quiz

Questions and Answers

1.

Which of the following is NOT true regarding the complement system?
- A.
  
  They are serum proteins that form protein cascades, each activated component activating the next to generate a physiologic response
- B.
  
  They can bind to bacteria, making holes in their membrane
- C.
  
  They attract phagocytes to both foreign material and self cells
- D.
  
  Binding of MBLs to a bacterial capsule triggers the complement cascade
- E.
  
  They help to eliminate immune complexes (antibody-antigen) and prevent them from damaging the body
2.

Which of the following key components of the complement pathway can be activated by the lectin, classical, and alternative pathways?
- A.
  
  C1
- B.
  
  C3
- C.
  
  C5
- D.
  
  C7
- E.
  
  C9
3.

Match the three types of molecules that recognize antigen with their description: Can create a soluble antigen receptor (antibody)
- A.
  
  B cell receptor (BCR)
- B.
  
  T cell receptor (TCR)
- C.
  
  Major histocompatibility complex (MHC)
4.

Match the three types of molecules that recognize antigen with their description: Recognize antigens bound to MHC
- A.
  
  B cell receptor (BCR)
- B.
  
  T cell receptor (TCR)
- C.
  
  Major histocompatibility complex (MHC)
5.

Match the three types of molecules that recognize antigen with their description: A cluster of genes that encode proteins
- A.
  
  B cell receptor (BCR)
- B.
  
  T cell receptor (TCR)
- C.
  
  Major histocompatibility complex (MHC)
6.

The genes encoding which of the following can undergo hypermutation to create receptors that are an even better fit for foreign antigens?
- A.
  
  BCRs
- B.
  
  TCRs
- C.
  
  MHCs
- D.
  
  BCRs & TCRs
- E.
  
  BCRs, TCRs, & MHCs
7.

Which of the following has an immunoglobulin fold?
- A.
  
  BCRs
- B.
  
  TCRs
- C.
  
  MHCs
- D.
  
  BCRs & TCRs
- E.
  
  BCRs, TCRs, & MHCs
8.

The genes encoding which of the following are extensively polymorphic (have multiple alleles or forms of the same gene)?
- A.
  
  BCRs
- B.
  
  TCRs
- C.
  
  MHCs
- D.
  
  BCRs & TCRs
- E.
  
  BCRs, TCRs, & MHCs
9.

What types of cell is class I MHC found on?
- A.
  
  B cells
- B.
  
  Macrophages
- C.
  
  Dendritic cells
- D.
  
  Essentially all cells
- E.
  
  Mainly on A, B, & C
10.

What types of cell is class II MHC found on?
- A.
  
  B cells
- B.
  
  Macrophages
- C.
  
  Dendritic cells
- D.
  
  Essentially all cells
- E.
  
  Mainly on A, B, & C
11.

What is the function of major histocompatibility complex (MHC) molecules?
- A.
  
  Present sugars to T cells
- B.
  
  Present peptides to T cells
- C.
  
  Create holes in the membranes of bacteria
- D.
  
  Lyse foreign antigens
- E.
  
  Phagocytize foreign antigens
12.

Unlike B cell receptors (BCRs), T cell receptors (TCRs) can only recognize foreign antigen if it is presented as a complex with a MHC molecule.
- A.
  
  True
- B.
  
  False
13.

If the structure of an individuals MHC molecules makes it impossible for them to recognize and bind any peptide antigen from a given virus, that individual will still be able to activate a T cell response to cells infected with that virus.
- A.
  
  True
- B.
  
  False
14.

Which of the following is NOT true about MHC molecules but true about B and T cells?
- A.
  
  The genes that encode molecules are the most variable genes we know of in the human genome (polygenic)
- B.
  
  They are extensively polymorphic (existence of multiple alleles or forms of the same gene)
- C.
  
  Every cell in each individual expresses the same set of molecules
- D.
  
  ) Every cell expresses a different molecule created from multiple gene segments that undergo somatic rearrangement
- E.
  
  Their diversity exists in the population as a whole, not in the individual
15.

Given that an individual’s parents have completely different HLA genes, that individual will have about____ different class I and II MHC molecules on the surface of certain of their lymphoid cells.
- A.
  
  3
- B.
  
  6
- C.
  
  9
- D.
  
  12
- E.
  
  15