They are serum proteins that form protein cascades, each activated component activating the next to generate a physiologic response
They can bind to bacteria, making holes in their membrane
They attract phagocytes to both foreign material and self cells
Binding of MBLs to a bacterial capsule triggers the complement cascade
They help to eliminate immune complexes (antibody-antigen) and prevent them from damaging the body
C1
C3
C5
C7
C9
B cell receptor (BCR)
T cell receptor (TCR)
Major histocompatibility complex (MHC)
B cell receptor (BCR)
T cell receptor (TCR)
Major histocompatibility complex (MHC)
B cell receptor (BCR)
T cell receptor (TCR)
Major histocompatibility complex (MHC)
BCRs
TCRs
MHCs
BCRs & TCRs
BCRs, TCRs, & MHCs
BCRs
TCRs
MHCs
BCRs & TCRs
BCRs, TCRs, & MHCs
BCRs
TCRs
MHCs
BCRs & TCRs
BCRs, TCRs, & MHCs
B cells
Macrophages
Dendritic cells
Essentially all cells
Mainly on A, B, & C
B cells
Macrophages
Dendritic cells
Essentially all cells
Mainly on A, B, & C
Present sugars to T cells
Present peptides to T cells
Create holes in the membranes of bacteria
Lyse foreign antigens
Phagocytize foreign antigens
True
False
True
False
The genes that encode molecules are the most variable genes we know of in the human genome (polygenic)
They are extensively polymorphic (existence of multiple alleles or forms of the same gene)
Every cell in each individual expresses the same set of molecules
) Every cell expresses a different molecule created from multiple gene segments that undergo somatic rearrangement
Their diversity exists in the population as a whole, not in the individual
3
6
9
12
15
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