Quiz: Immunology Multiple Choice Questions

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Quiz: Immunology Multiple Choice Questions

The immune system is our shield against diseases and various infectious organisms that try to invade our body. It's a host defense system which is built of many biological structures. So, here in this quiz, you shall face more than forty basic to advance multiple-choice questions of the same that will determine how good your knowledge is of the topic. So, let's get started!


Questions and Answers
  • 1. 
    • A. 

      Immune Response.

    • B. 

      Skin and Mucous membranes.

    • C. 

      Inflammatory response.

    • D. 

      Inflammatory response and skin and mucous membranes.

  • 2. 
    Second Line of Defense:
    • A. 

      Immune Response.

    • B. 

      Skin and Mucous membranes.

    • C. 

      Inflammatory response.

    • D. 

      Inflammatory response and skin and mucous membranes.

  • 3. 
    Third Line of defense:
    • A. 

      Immune Response.

    • B. 

      Skin and Mucous membranes.

    • C. 

      Inflammatory response.

    • D. 

      Inflammatory response and skin and mucous membranes.

  • 4. 
    Innate defense system:
    • A. 

      Immune Response.

    • B. 

      Skin and Mucous membranes.

    • C. 

      Inflammatory response.

    • D. 

      Inflammatory response and skin and mucous membranes.

  • 5. 
    Adaptive defense system:
    • A. 

      Immune Response.

    • B. 

      Skin and Mucous membranes.

    • C. 

      Inflammatory response.

    • D. 

      Inflammatory response and skin and mucous membranes.

  • 6. 
    Small Proteins secreted by virus-containing cells:
    • A. 

      Regulatory T cells.

    • B. 

      Helper T cells.

    • C. 

      Complement.

    • D. 

      Interferon.

    • E. 

      Macrophage APCs.

  • 7. 
    Major Innate mechanism that mediates destruction of foreign substances in the body:
    • A. 

      Regulatory T cells.

    • B. 

      Helper T Cells.

    • C. 

      Complement.

    • D. 

      Interferon.

    • E. 

      Macrophage APCs.

  • 8. 
    Stimulate the proliferation of other lymphocytes:
    • A. 

      Regulatory T cells.

    • B. 

      Helper T Cells.

    • C. 

      Complement.

    • D. 

      Interferon.

    • E. 

      Macrophage APCs.

  • 9. 
    Present the double activation signal to T cells:
    • A. 

      Regulatory T cells.

    • B. 

      Helper T Cells.

    • C. 

      Complement.

    • D. 

      Interferon.

    • E. 

      Macrophage APCs.

  • 10. 
    Main antibody of both primary and secondary immune response:
    • A. 

      IgG

    • B. 

      IgA

    • C. 

      IgD

    • D. 

      IgE

    • E. 

      IgM

  • 11. 
    Protects mucosal barriers:
    • A. 

      IgG

    • B. 

      IgA

    • C. 

      IgD

    • D. 

      IgE

    • E. 

      IgM

  • 12. 
    Involved in allergies:
    • A. 

      IgG

    • B. 

      IgA

    • C. 

      IgD

    • D. 

      IgE

    • E. 

      IgM

  • 13. 
    Along with IgM, this is a B cell receptor:
    • A. 

      IgG

    • B. 

      IgA

    • C. 

      IgD

    • D. 

      IgE

    • E. 

      IgM

  • 14. 
    Activates Complement:
    • A. 

      IGG

    • B. 

      IGA

    • C. 

      IgD

    • D. 

      IgE

    • E. 

      IgM

  • 15. 
    A graft from a monkey to a human is an example of an allograft.
    • A. 

      True

    • B. 

      False

  • 16. 
    The mechanism of the "lethal hit" of cytotoxic T cells involves a protein called perforin.
    • A. 

      True

    • B. 

      False

  • 17. 
    Cellular ingestion and destruction of particulate matter are called phagocytosis.
    • A. 

      True

    • B. 

      False

  • 18. 
    The respiratory burst produced by some macrophages releases free radicals.
    • A. 

      True

    • B. 

      False

  • 19. 
    The directional movement of cells in response to chemicals is called chemotaxis.
    • A. 

      True

    • B. 

      False

  • 20. 
    • A. 

      True

    • B. 

      False

  • 21. 
    Soluble proteins secreted by plasma cells are called antibodies.
    • A. 

      True

    • B. 

      False

  • 22. 
    Tolerance for self-antigens is abnormal.
    • A. 

      True

    • B. 

      False

  • 23. 
    Fever is seldom beneficial because it speeds up the cellular metabolic rate and will not allow antigen-antibody reactions to occur.
    • A. 

      True

    • B. 

      False

  • 24. 
    Monoclonal antibodies can be specific for several antigenic determinants.
    • A. 

      True

    • B. 

      False

  • 25. 
    Autoimmune diseases are more common in men than in women.
    • A. 

      True

    • B. 

      False

  • 26. 
    Some immunocompetent cells will never be called to service in our lifetime.
    • A. 

      True

    • B. 

      False

  • 27. 
    Atopy is an inherited tendency to spontaneously develop immediate (type I) allergies to certain environmental antigens.
    • A. 

      True

    • B. 

      False

  • 28. 
    Adaptive immunity is provided by lymphocytes that secrete antibodies.
    • A. 

      True

    • B. 

      False

  • 29. 
    A transfusion reaction is a aubacute hypersensitivity to foreign red blood cells.
    • A. 

      True

    • B. 

      False

  • 30. 
    During fetal development, lymphocytes that do not react to self-antigens are destroyed.
    • A. 

      True

    • B. 

      False

  • 31. 
    Somatic recombination by B cells allows each B cell to form its own unique antibody genes.
    • A. 

      True

    • B. 

      False

  • 32. 
    Perforins are cytolytic chemicals used by NK cells.
    • A. 

      True

    • B. 

      False

  • 33. 
    Antigens can be complete or incomplete.
    • A. 

      True

    • B. 

      False

  • 34. 
    It is our genes, not antigens, that determine what specific foreign substances our immune system will be able to recognize and resist.
    • A. 

      True

    • B. 

      False

  • 35. 
    Which of the following is characteristic of antibodies?
    • A. 

      Carbohydrate structure.

    • B. 

      Composed of heavy and light polypeptide chains.

    • C. 

      Three binding sites per antibody monomer.

    • D. 

      Incapable of being transferred from one person to another.

  • 36. 
    Which of the following is associated with passive immunity?
    • A. 

      Long-term immune protection.

    • B. 

      Infusion of weakened viruses.

    • C. 

      Passage of IgG antibodies from the pregnant mother to her fetus.

    • D. 

      Booster shot.

  • 37. 
    Which of the following is not a type T cell?
    • A. 

      Cytotoxic

    • B. 

      Antigenic

    • C. 

      Helper

    • D. 

      Regulatory

  • 38. 
    B lymphocytes develop immunocompetence in the _______.
    • A. 

      Thymus

    • B. 

      Spleen

    • C. 

      Bone marrow

    • D. 

      Lymph nodes

  • 39. 
    • A. 

      Prevents the spread of the injurious agent to nearby tissue.

    • B. 

      Replaces injured tissues with connective tissue.

    • C. 

      Disposes of cellular debris and pathogens.

    • D. 

      Sets the stage for repair processes.

  • 40. 
    The redness and heat of an inflammed area are due to a local hyperemia caused by ______.
    • A. 

      Vasodialation.

    • B. 

      Vasoconstriciton.

    • C. 

      Phagocyte mobilization.

    • D. 

      Production of complement and interferon.

  • 41. 
    The antibody molecule is held together by ______ bonds.
    • A. 

      Disulfide

    • B. 

      Hydrogen

    • C. 

      Amino acid

    • D. 

      Sodium

  • 42. 
    In clonal selection of B cells, which substance is responsible for determining which cells will eventually become cloned?
    • A. 

      Antigen

    • B. 

      Lymphocyte

    • C. 

      Antibody

    • D. 

      Macrophage

  • 43. 
    The system that recognizes foreign molecules and acts to immobilize, neutralize, or destroy them is the _________.
    • A. 

      Integumentary system.

    • B. 

      Renal system.

    • C. 

      Immune system.

    • D. 

      Lymphatic system.

  • 44. 
    The process whereby neutrophils and other white blood cells are attracted to an inflammatory site is called _________.
    • A. 

      Diapedesis

    • B. 

      Chemotaxis

    • C. 

      Margination

    • D. 

      Phagocytosis

  • 45. 
    Small molecules that bind with self-proteins to produce antigenic substances are called ____.
    • A. 

      Haptens

    • B. 

      Antibodies

    • C. 

      Ions

    • D. 

      Reagins

  • 46. 
    The chief antibody-mediated mechanism used against cellular antigens, such as bacteria, is _______.
    • A. 

      Interferon production

    • B. 

      Complement fixation

    • C. 

      Neutralization

    • D. 

      Agglutination

  • 47. 
    The only T cells that can directly attack and kill other cells are the ______.
    • A. 

      Regulatory cells

    • B. 

      Helper cells

    • C. 

      Cytotoxic cells

    • D. 

      Plasma cells

  • 48. 
    Select the correct statement about phagocytic cells.
    • A. 

      Neutrophils may destroy themselves when they phagocytize large quantities of a foreign substance.

    • B. 

      Macrophages release defensins during killing.

    • C. 

      The respiratory burst characterizes eosinophil phagocytosis.

    • D. 

      Kupffer cells are a type of neutrophil.