This examination covers the basics of Immunology and Serology that a Medical Technology student must know. This 70-item exam has a time limit of 60 minutes only. Please enter your name in the required field.
A hapten when combined with a carrier can elicit the formation of antibodies.
Complete Freund's Adjuvant can stimulate cellular immunity.
IgG is the best complement fixing immunoglobulin.
Anaphylaxis is an immediate hypersensitivity reaction that causes bronchoconstriction.
CH1
CH2
CH3
CH4
Natural active immunity
Natural passive immunity
Artificial active immunity
Artificial passive immunity
Immune adherence
Complement fixation
Opsonization
Immune complex formation
The method of complement assay that involves the measurement of precipiting ring diameter after 48 hours is Fahey McKelvey.
Type I hypersensitivity is known as the "cytotoxic type".
CD19, CD20, and CD21 are subtypes of B cells.
The C5 convertase in the Classical Pathway of complement activation is C4b2b3b.
Phagocytosis
CRP
Lysozyme
Complement
Graft rejection
Autoimmune diseases
Determining to which agents an individual responds
All of the above
Internal complexity
Large molecular weight
The presence of numerous epitopes
Found on host cells
Readings are taken before equivalence is reached.
Concentration is directly proportional to the square of the diameter.
The diameter is plotted against the log of the concentration.
It is primarily a qualitative rather than a quantitative method.
Direct agglutination
Passive agglutination
Reverse passive agglutination
Agglutination inhibition
Hemolytic disease of the newborn
Autoimmune hemolytic anemia
Antibodies to drugs that bind to red cells
Any of the above
19.8 mL
4.0 mL
3.8 mL
10.0 mL
Can cross the placenta
Fixes complement
Has a J chain
Is a primary response antibody
Type A
Type B
Type O
Type AB
Phagocytosis
Variolation
Humoral immunity
Opsonization
Increased blood supply to the area
Migration of white blood cells
Decreased capillary permeability
Appearance of acute phase reactants
False-negative result
False-positive result
No effect
Slight but can be ignored
Roswell Park Memorial Institute
Ficolle medium
Phosphate buffered saline
Normal saline solution (0.9% NaCl)
To destory the native complement
To remove heat labile anti-complementary substances
To stabilize the serologic properties of the serum
All of the above
56 degrees Celsius, 30 minutes
56 degrees Celsius, 10 minutes
65 degrees Celsius, 20 minutes
65 degrees Celsius, 10 minutes
Papain
Pepsin
Sodium polyanethol
Dithiothreitol
I
II
III
IV
Epitope.
Paratope.
Valence.
Any of the above
Serum inactivation is required.
These are examples of indirect agglutination tests.
Both are classified as TTT.
These are non-specific for syphilis.
Natural
Acquired
Adaptive
Auto
Lymph node
Spleen
Thymus
Mucosal associated lymphoid tissue
CD3
CD4
CD8
CD11
IgG and IGD
IgM and IgD
Alpha and beta chains
CD3 and CD4
H chains
IgM molecules
L chains
IgG molecules
1:25
1:4
1:96
4:1
Human erythocytes
Horse erythrocytes
Sheep erythrocytes
B and C
It is only active at 25 degrees Celsius.
It may be to small to produce lattice formation.
It only has one antigen-binding site.
It is not able to prodice visible in vivo agglutination.
Cellular antigens are involved.
Deposition of immune complexes occurs in atibody excess.
Only heterologous antigens are involved.
Tissue damage results from exocytosis.
Incubating longer than 5 minutes.
Not washing red cells thoroughly.
Using EDTA anticoagulated blood.
Presence of IgG on red cells.
Dick's test
Casoni test
Bachman test
Schick's test
Phagolysosome formation
Exocytosis
Antigen epitope presentation by HLA
Lysosome formation
The specimen for Class II HLA typing is pure B cells.
The specimen for RID C3c assay is inactivated serum.
Eosin is added to neutrophil-bacterial suspension in the intacellular killing assay.
In the ABO blood group system, serum typing is an example of an indirect agglutination reaction.
NBT dye is colored yellow-orange when added to inactive neutrophils.
A green fluorescence seen on a fluorescence microscope after addition of acridine orange represent alive organisms.
CD4 receptors are responsible for the rosette formation of sheep erythrocytes.
Proteus organisms are used as antigens for Weil Felix test.
Fails to fix complement
Is heat stable
Attaches to tissue mast cells
Is found in the seurm of allergic persons
Kappa
Gamma
Mu
Alpha
Phagosome.
Vacuole.
Lysosome.
Phagolysosome.
Reactions in VDRL can be seen macroscopically as dense flocculates.
CSF can be used as a specimen for VDRL.
Serum inactivation is not needed in VDRL.
All of the above
Humoral response
Plasma cells
Cytokines
Antibody
Protection of the mucous membranes
Removal of antigens by complement fixation
Enhancing the proliferation of B cells
Destruction of parasitic worms
It consists of C1q, C1r, and C1s.
The subunits require calcium for binding together.
It is a part of the Properdin Pathway.
C1q activates C4.
The dilution of patient serum required to lyse 50 percent of a standard concentration of sensitized sheep red blood cells
Functioning of both the classical and alternative pathway
Genetic deficiencies of any of the complement components
All of the above
"O" antigens
"K" antigens
"H" antigens
"Vi" antigens
Antigens 1 and 2 are identical.
Antigen 2 is simpler than antigen 1.
Antigen 2 is more complex than anitgen 1.
The two antigens are unrelated.
IgG
IgM
IgD
IgE
IgA
Ehrlich
Haurowitz and Breini
Jerne and MacFarlane
Claman
Humoral immunity primarily involves B lymphocytes.
The variable region of an antibody molecule is responsible for its sensitivity.
Complement components are under Class II of HLA molecules.
None of the above
Pluripotential stem cells
Lymphoid stem cells
Pre-B cells
Myeloid stem cells
SMIg+ B cells adhere to the nylon wool and are therefore eluted last.
SMIg- B cells adhere to the nyloon wool and are therefore eluted first.
SMIg+ T cells adhere to the nylon wool and are therefore eluted last.
SMIg+ T cells adhere to the nylon wool and are therefore eluted first.
Immune complexes activate the pathway.
Cobra venom factor, aggregated IgA's , and baterial LPS activate the pathway.
A and B
None of the above
SLE
Early syphilis
Biologic false positive reaction
IM
IgG
IgM
IgD
IgE
IgA
Intact skin
Phagocytosis
Cell mediated immunity
Humoral immunity
SMDP
GNB
Complete Freund's Adjuvant
None of the above
Immune serum
Toxoid
A or B
None of the above
Xenograft
Autograft
Allograft
Syngeneic graft
Heterograft
Rocy Mountain Spotted Fever
Trench fever
Rickettsial pox
Tsutsugamushi fever
Urine
CSF
Serum
All of the above
Colon cancer
Ovarian cancer
Prostate cancer
Hepatoma
Homogenous or solid
Peripheral or rim
Speckled
Nucleolar
Bone marrow
Corneal
Bone matrix
Lung
Escherichia coli
Proteus spp.
Brucella spp.
Salmonella typhi
IgM
IgG
IgA
IgD
IgE
HBs Ag
HBe Ag
Anti-HBc
Anti-HBe
Anti-HBs