Immunology Quiz- Basic Concepts
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Basic ConceptsBasic ConceptsBasic Concepts
- 1.Antigen presenting cells (APCs) include macrophages and dendritic cells, which are found in lymphoid tissues and the____. These are critical in the uptake and presentation of antigen to T cells.
- A.
Liver
- B.
Kidney
- C.
Skin
- 2.Which of the following is NOT a major feature (characteristic) of the adaptive immune system?
- A.
Specificity
- B.
Diversity
- C.
Memory
- D.
Improvement
- E.
Speed
- 3.Humoral immunity is mediated by antibodies from____ and is involved in the elimination of____ pathogens. Cell mediated immunity is mediated by____ and is involved in the elimination of____ pathogens
- A.
B lymphocytes; Intracellular; T lymphocytes; Extracellular
- B.
B lymphocytes; Extracellular; T lymphocytes; Intracellular
- C.
T lymphocytes; Intracellular; B lymphocytes; Extracellular
- D.
T lymphocytes; Extracellular; B lymphocytes; Intracellular
- 4.How many doses of the Hepatitis B vaccine (5µg HBsAg in 0.5mL intramuscular) are required to reach a protective level of antibody?
- A.
1
- B.
2
- C.
3
- D.
4
- E.
5
- 5.Match the following innate immune system cell types with their function: Eosinophils
- A.
Phagocytosis and bacteriocidal mechanisms, antigen presentation
- B.
Lysis of some virally infected cells
- C.
Killing parasites
- D.
Release of histamine and other mediators
- E.
Phagocytosis and bacteriocidal mechanisms
- 6.Match the following innate immune system cell types with their function: Macrophages
- A.
Phagocytosis and bacteriocidal mechanisms, antigen presentation
- B.
Lysis of some virally infected cells
- C.
Killing parasites
- D.
Release of histamine and other mediators
- E.
Phagocytosis and bacteriocidal mechanisms
- 7.
- A.
Phagocytosis and bacteriocidal mechanisms, antigen presentation
- B.
Lysis of some virally infected cells
- C.
Killing parasites
- D.
Release of histamine and other mediators
- E.
Phagocytosis and bacteriocidal mechanisms
- 8.Match the following innate immune system cell types with their function: Natural killer cells
- A.
Phagocytosis and bacteriocidal mechanisms, antigen presentation
- B.
Lysis of some virally infected cells
- C.
Killing parasites
- D.
Release of histamine and other mediators
- E.
Phagocytosis and bacteriocidal mechanisms
- 9.Match the following innate immune system cell types with their function: Neutrophils
- A.
Phagocytosis and bacteriocidal mechanisms, antigen presentation
- B.
Lysis of some virally infected cells
- C.
Killing parasites
- D.
Release of histamine and other mediators
- E.
Phagocytosis and bacteriocidal mechanisms
- 10.T cells are made in the____ and complete their differentiation in the____.
- A.
Spleen; Thyroid
- B.
Spleen; Thymus
- C.
Bone marrow; Thyroid
- D.
Bone marrow; Thymus
- E.
Bone marrow; Thalamus
- 11.In a resting lymphocyte, B cells and T cells can be distinguished from each other via a simple blood smear
- A.
True
- B.
False
- 12.Which of the following is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?
- A.
Cluster of differentiation 4 (CD4+)
- B.
Cluster of differentiation 8 (CD8+)
- C.
Plasma cells (activated B cells)
- 13.Which of the following produce large amounts of antibodies (Igs) and differentiate upon stimulation from CD4+ cells?
- A.
Cluster of differentiation 4 (CD4+)
- B.
Cluster of differentiation 8 (CD8+)
- C.
Plasma cells (activated B cells)
- 14.Which of the following is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells?
- A.
Cluster of differentiation 4 (CD4+)
- B.
Cluster of differentiation 8 (CD8+)
- C.
Plasma cells (activated B cells)
- 15.An individual is bitten by a dog with rabies and begins to develop antibodies againstthe rabies. These antibodies are harvested and transferred to unimmunized individuals toconfer protection more rapidly for these individuals. This is an example of:
- A.
Active immunity
- B.
Passive immunity
- 16.Match the stage of an adaptive (acquired) immune response with the description: Proliferation of cells with matching receptors
- A.
Cognitive phase
- B.
Activation phase
- C.
Effector phase
- 17.
- A.
Cognitive phase
- B.
Activation phase
- C.
Effector phase
- 18.Match the stage of an adaptive (acquired) immune response with the description: Recognition of antigen
- A.
Cognitive phase
- B.
Activation phase
- C.
Effector phase
- 19.What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?
- A.
Cognitive phase
- B.
Activation phase
- C.
Effector phase
- 20.
- A.
Macrophage
- B.
Dendritic cell
- C.
B cell
- 21.Which of the following types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells?
- A.
Macrophage
- B.
Dendritic cell
- C.
B cell
- 22.Which of the following types of antigen presenting cells (APCs) is specialized for degradation and presentation of particulate antigens to T cells?
- A.
Macrophage
- B.
Dendritic cell
- C.
B cell
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