Immunology General

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  • 1/23 Questions

    A specific antibody binds to a specific binding site on an antigen, this area on the antigen where the antibody binds is called __________

    • Immunogenicity
    • Haptope
    • Eptitope
    • Immunoglobulins
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About This Quiz

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Immunology Quizzes & Trivia

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  • 2. 

    Which compliment pathway involves the C1 protein and is activated by the antigen-antibody complexes?

    • Alternative

    • MBL

    • Classical

    • MAC

    Correct Answer
    A. Classical
  • 3. 

    Humoral immunity is associated with which type of cell?

    • Natural Killer Cells

    • T Cells

    • B Cells

    • Innate Cells

    Correct Answer
    A. B Cells
    Explanation
    Humoral is associated with B cells. Cellular immunity is associated with T cells. Both are adaptive defence mechanisms.

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  • 4. 

    The alternative pathway is usually triggered without anitbody involvement

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Slide 18

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  • 5. 

    Haptens alone can trigger an immune response

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Hapens need to be attached to a body protein or to an antibody molecule already formed in order to illicit an immune response.

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  • 6. 

    Which class of antibody has 10 binding sites?

    • IgM

    • IgE

    • IgA

    • IgD

    • IgG

    Correct Answer
    A. IgM
  • 7. 

    A patient is sick and their blood levels indicate higher amounts of IgM compared with IgG, this is most likely

    • The patients first exposure to the antigen

    • The patients second exposure to the antigen

    • Going to be associated with a long lived response

    • A secondary immune response

    Correct Answer
    A. The patients first exposure to the antigen
    Explanation
    This is characteristic of a primary immune response. All the others are characteristics of a secondary immune response.

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  • 8. 

    An Anaphylactic reaction is associated with abnormal production of which antibody?

    • IgD

    • IgE

    • All Antibodies

    • No Antibodies

    Correct Answer
    A. IgE
  • 9. 

    Which of the following is an example of naturally acquired specific immunity?

    • Vaccination

    • Placental transfer of anitbodies

    • Administration of anitoxin

    • Interferons

    Correct Answer
    A. Placental transfer of anitbodies
    Explanation
    Placental transfer is naturally acquired (passive) specific immunity. Vaccination (active) and administration of antitoxin (passive) are examples of artificially acquired specific immunity. Interferons are not specific immunity but rather innate immunity.

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  • 10. 

    Shortly after birth and before a newborn can produce its own antibodies, what is the only antibody class protecting the newborn?

    • IgA

    • IgM

    • IgG

    • All of the options

    Correct Answer
    A. IgG
    Explanation
    IgG is the only antibody class that can pass the placental barrier and so this is the only class that the baby will have in its body.

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  • 11. 

    Helper T cells recognize antigen fragments associated with __________ where as Cytotoxic T cells recognize fragments associated with ______.

    • MHC-2 molecules, MHC-1 molecules

    • MHC-1 molecules, MHC-2 molecules

    • MHC-1 molecules, MHC-1 molecules

    • MHC-2 molecules, MHC-2 molecules

    Correct Answer
    A. MHC-2 molecules, MHC-1 molecules
    Explanation
    Slide 42

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  • 12. 

    Where would you find low levels of IgA?

    • Mucosal surfaces

    • General blood circulation

    • Breast Milk

    • Saliva

    Correct Answer
    A. General blood circulation
    Explanation
    Slide 22

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  • 13. 

    T lymphocytes are more abundant in circulating blood than B lymphocytes

    • True

    • False

    Correct Answer
    A. True
    Explanation
    T lymphocytes = 70%. B lymphocytes = 15%

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  • 14. 

    If a person was diagnosed with AIDS, which of the following would you expect to see from their blood results?

    • CD4+ T Cells outnumbering the CD8+ T cells

    • Cytotoxic T cells outnumbering the Helper T cells

    • A ration of 1:1 between CD4 and CD8 T cells

    • No abnormality in blood lymphocyte make up

    Correct Answer
    A. Cytotoxic T cells outnumbering the Helper T cells
    Explanation
    The normal ration between CD4 (Helper T cells) and CD8 (Cytotoxic T cells) is 2:1. In AIDS, it is 0.5:1

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  • 15. 

    Which of the following compliment pathways is the final pathway?

    • Classical Pathway

    • Alternative Pathway

    • MBL

    • MAC

    Correct Answer
    A. MAC
    Explanation
    MAC (Membrane attack complex) is what kills the cell by puncturing its membrane and destroying the pathogens internal stasis.

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  • 16. 

    A cell becomes infected with a virus and begins to produce proteins that signal nearby cells to produce antivirual proteins. What are the signal proteins called?

    • Cytokines

    • Interferons

    • Phagocytic proteins

    • Antigen presenting complex

    Correct Answer
    A. Interferons
  • 17. 

    Cell mediated immunity (Select 2)

    • Is carried out primarily by T cells

    • Is more effective against intracellular pathogens

    • Is carried out primarily by B cells

    • Is more effective against extracellular pathogens

    Correct Answer(s)
    A. Is carried out primarily by T cells
    A. Is more effective against intracellular pathogens
    Explanation
    B cells are responsible for the other 2 options.

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  • 18. 

    Which of the following is true regarding IgM? (Select 2)

    • It is the first antibody produced in response to infection

    • It requires class switching

    • It has 2 forms - surface form and secreted form

    • The compliment system is blind to IgM

    Correct Answer(s)
    A. It is the first antibody produced in response to infection
    A. It has 2 forms - surface form and secreted form
    Explanation
    IgM does not require class switching and this is partially why it is the first antibody in response (less processing time). It is not blind to the compliment system, it is actually a good stimulator of the compliment system.

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  • 19. 

    Which portion of the antibody binds with the antigen? (Select 2)

    • Fc

    • Crystallizable

    • Variable

    • FAB

    Correct Answer(s)
    A. Variable
    A. FAB
    Explanation
    Fc and Crystallizable are the same thing.

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  • 20. 

    Nonspecific innate immunity is present shortly after birth (2-4 weeks)

    • True

    • False

    Correct Answer
    A. False
    Explanation
    It is present from birth

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  • 21. 

    Which of the following are examples of first or second line of defences in the body? (select all that apply)

    • Mucous membranes

    • Enzymes in secretions

    • Interferon

    • Vaccinations

    Correct Answer(s)
    A. Mucous membranes
    A. Enzymes in secretions
    A. Interferon
    Explanation
    Vaccination is third line of defence (specific immunity) and is artificially acquired (active)

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  • 22. 

    Which of the following is true regarding the primary immune response?

    • It is carried out by innate cells

    • It is part of the specific immune response

    • It is the skin barrier preventing entry of a pathogen

    • It is the mucous barrier lining epithelial cells

    Correct Answer
    A. It is part of the specific immune response

Quiz Review Timeline (Updated): Feb 1, 2016 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Feb 01, 2016
    Quiz Edited by
    ProProfs Editorial Team
  • Jan 23, 2016
    Quiz Created by
    Eddy Sidra
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