Immunology General
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Handout 1 and 2
- 1.Which of the following is an example of naturally acquired specific immunity?
- A.
Vaccination
- B.
Placental transfer of anitbodies
- C.
Administration of anitoxin
- D.
Interferons
- 2.Which of the following are examples of first or second line of defences in the body? (select all that apply)
- A.
Mucous membranes
- B.
Enzymes in secretions
- C.
Interferon
- D.
Vaccinations
- 3.Nonspecific innate immunity is present shortly after birth (2-4 weeks)
- A.
True
- B.
False
- 4.Which of the following compliment pathways is the final pathway?
- A.
Classical Pathway
- B.
Alternative Pathway
- C.
MBL
- D.
MAC
- 5.Which compliment pathway involves the C1 protein and is activated by the antigen-antibody complexes?
- A.
Alternative
- B.
MBL
- C.
Classical
- D.
MAC
- 6.The alternative pathway is usually triggered without anitbody involvement
- A.
True
- B.
False
- 7.A cell becomes infected with a virus and begins to produce proteins that signal nearby cells to produce antivirual proteins. What are the signal proteins called?
- A.
Cytokines
- B.
Interferons
- C.
Phagocytic proteins
- D.
Antigen presenting complex
- 8.Humoral immunity is associated with which type of cell?
- A.
Natural Killer Cells
- B.
T Cells
- C.
B Cells
- D.
Innate Cells
- 9.Which of the following is true regarding the primary immune response?
- A.
It is carried out by innate cells
- B.
It is part of the specific immune response
- C.
It is the skin barrier preventing entry of a pathogen
- D.
It is the mucous barrier lining epithelial cells
- 10.T lymphocytes are more abundant in circulating blood than B lymphocytes
- A.
True
- B.
False
- 11.If a person was diagnosed with AIDS, which of the following would you expect to see from their blood results?
- A.
CD4+ T Cells outnumbering the CD8+ T cells
- B.
Cytotoxic T cells outnumbering the Helper T cells
- C.
A ration of 1:1 between CD4 and CD8 T cells
- D.
No abnormality in blood lymphocyte make up
- 12.Helper T cells recognize antigen fragments associated with __________ where as Cytotoxic T cells recognize fragments associated with ______.
- A.
MHC-2 molecules, MHC-1 molecules
- B.
MHC-1 molecules, MHC-2 molecules
- C.
MHC-1 molecules, MHC-1 molecules
- D.
MHC-2 molecules, MHC-2 molecules
- 13.Cell mediated immunity (Select 2)
- A.
Is carried out primarily by T cells
- B.
Is more effective against intracellular pathogens
- C.
Is carried out primarily by B cells
- D.
Is more effective against extracellular pathogens
- 14.A patient is sick and their blood levels indicate higher amounts of IgM compared with IgG, this is most likely
- A.
The patients first exposure to the antigen
- B.
The patients second exposure to the antigen
- C.
Going to be associated with a long lived response
- D.
A secondary immune response
- 15.A specific antibody binds to a specific binding site on an antigen, this area on the antigen where the antibody binds is called __________
- A.
Immunogenicity
- B.
Haptope
- C.
Eptitope
- D.
Immunoglobulins
- 16.Haptens alone can trigger an immune response
- A.
True
- B.
False
- 17.Which portion of the antibody binds with the antigen? (Select 2)
- A.
Fc
- B.
Crystallizable
- C.
Variable
- D.
FAB
- 18.Which class of antibody has 10 binding sites?
- A.
IgM
- B.
IgE
- C.
IgA
- D.
IgD
- E.
IgG
- 19.Which of the following is true regarding IgM? (Select 2)
- A.
It is the first antibody produced in response to infection
- B.
It requires class switching
- C.
It has 2 forms - surface form and secreted form
- D.
The compliment system is blind to IgM
- 20.Where would you find low levels of IgA?
- A.
Mucosal surfaces
- B.
General blood circulation
- C.
Breast Milk
- D.
Saliva
- 21.Shortly after birth and before a newborn can produce its own antibodies, what is the only antibody class protecting the newborn?
- A.
IgA
- B.
IgM
- C.
IgG
- D.
All of the options
- 22.An Anaphylactic reaction is associated with abnormal production of which antibody?
- A.
IgD
- B.
IgE
- C.
All Antibodies
- D.
No Antibodies
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