Hematology: Leukopoiesis, Blood Smear, And Cytochemistry

45 Questions | Total Attempts: 500

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Hematology: Leukopoiesis, Blood Smear, And Cytochemistry

This is a 40 item quiz. 15 items per topic. Time limit is 50 minutes. This is not meant to substitute studying. This is merely to simulate the test. This is not taken from any source other than the notes given by the lecturers.


Questions and Answers
  • 1. 
    The common progenitor cell for granulocytes and monocytes which gives rise to the myeloblase
    • A. 

      GM-CSF

    • B. 

      Eo-CSF

    • C. 

      GM-CFC

    • D. 

      A and C

    • E. 

      None of the above

  • 2. 
    Has more azurophil granules and less specific granules
    • A. 

      Early neutrophi myelocyte

    • B. 

      Late neutrophil myelocyte

    • C. 

      Both

    • D. 

      Neither

  • 3. 
    Appearance of specific granules
    • A. 

      Early neutrophi myelocyte

    • B. 

      Late neutrophi myelocyte

    • C. 

      Both

    • D. 

      Neither

  • 4. 
    They proliferate in response to immunologic stimulation (e.g. allergic reactions)
    • A. 

      Neutrophils

    • B. 

      Eosinophils

    • C. 

      Basophils

    • D. 

      Monocytes

    • E. 

      Lymphocytes

  • 5. 
    Stage when cell may be recognized specifically as a neutrophil, eosinophil, or basophil.
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Stab Form

  • 6. 
    Has a ground-glass appearance
    • A. 

      Metamyelocyte

    • B. 

      Megakaryocyte

    • C. 

      Promyelocyte

    • D. 

      Myeloblast

    • E. 

      Promonocyte

  • 7. 
    Has a pale clear blue cytoplasm
    • A. 

      Metamyelocyte

    • B. 

      Megakaryocyte

    • C. 

      Promyelocyte

    • D. 

      Myeloblast

    • E. 

      Promonocyte

  • 8. 
    Last stage capable of cell division
    • A. 

      Myeloblast

    • B. 

      Promonocyte

    • C. 

      Myelocyte

    • D. 

      Band form

    • E. 

      Segmented form

  • 9. 
    Has an indented kidney shaped nucleus
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Stab form

  • 10. 
    Also called a "juvenile cell"
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Megakaryoblast

  • 11. 
    Has a partially constricted nucleus
    • A. 

      Segmented form

    • B. 

      Band form

    • C. 

      Metamyelocyte

    • D. 

      Myelocyte

    • E. 

      Promyelocyte

  • 12. 
    Has a streaked chromatin pattern
    • A. 

      Monocyte

    • B. 

      Megakaryocyte

    • C. 

      Neutrophilic Myelocyte

    • D. 

      Mast cells

    • E. 

      Plasma cells

  • 13. 
    Contain heparin, peroxidase, and histamine
    • A. 

      Neutrophil

    • B. 

      Basophil

    • C. 

      Eosinophil

    • D. 

      Mast cells

    • E. 

      B and D

  • 14. 
    Nucleus has a horse-shoe appearnace
    • A. 

      Megakaryoblast

    • B. 

      Promegakaryocyte

    • C. 

      Granular megakaryocyte

    • D. 

      Mature megakaryocyte

    • E. 

      A and B only

  • 15. 
    Stage where azurophil granules start to appear
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Stab form

  • 16. 
    What can be used as a substitute of the buffer solution?
    • A. 

      1N NaOH

    • B. 

      NSS

    • C. 

      0.85% NaCl

    • D. 

      Distilled water

    • E. 

      B and C

  • 17. 
    What has grayish to lilac granules?
    • A. 

      Neutrophil

    • B. 

      Basophil

    • C. 

      Eosinophil

    • D. 

      Monocyte

    • E. 

      Lymphocyte

  • 18. 
    Which are the characteristics of a good smear?
    • A. 

      Has a smooth even appearance with no holes, ridges, or a wavy appearance.

    • B. 

      Exhibits tailing at the end of the thin portion

    • C. 

      There is a gradual transition from the thick to thin portion

    • D. 

      The smear does not cover the entire length of the slide

    • E. 

      Cells should be closely clumped to one another

  • 19. 
    What does a metallic sheen indicate?
    • A. 

      Dirty slide

    • B. 

      There is staining of the cells

    • C. 

      Proper stain:buffer ratio

    • D. 

      All of the above

    • E. 

      A and B

  • 20. 
    What is the remedy if RBCs stain blue or green?
    • A. 

      Use more diluents

    • B. 

      Shorten staining time

    • C. 

      Make buffer solution slightly acidic

    • D. 

      All of the above

    • E. 

      A and B only

  • 21. 
    Check the causes of precipitates on s stained blood film
    • A. 

      Inadequate washing

    • B. 

      Inadequate filtration of the stain

    • C. 

      Drying during the period of staining

    • D. 

      Overflowing the stain

    • E. 

      Dirty glass slides

  • 22. 
    Staining should be performed within _____ after making the film
    • A. 

      30 min

    • B. 

      1 hr

    • C. 

      1 hr and 30min

    • D. 

      2 hrs

    • E. 

      3-4 hrs

  • 23. 
    Delayed smearing may cause: (select appropriate answer/s)
    • A. 

      Wavy appearance of the smear

    • B. 

      Holes and ridges on the smear

    • C. 

      Abnormal distribution of WBCs

    • D. 

      Rouleaux formation of RBCs

    • E. 

      Clumping of platelets

  • 24. 
    What causes ridges on the smear?
    • A. 

      Jerky movement

    • B. 

      Large blood sample

    • C. 

      Small blood sample

    • D. 

      Rough edges of the spreader slide

    • E. 

      Incorrect angle of the spreader slide

  • 25. 
    If the drop of blood gets ahead of the spreader slide, what occurs?
    • A. 

      Wavy appearance of the slide

    • B. 

      Cell distortion

    • C. 

      Holes

    • D. 

      Ridges

    • E. 

      All of the above

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