Basic Hematology Concepts / Laboratory Procedures

35 Questions | By Melissa3393 | Last updated: Feb 28, 2013 | Total Attempts: 8064

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MLT questions for ASCP examination

Questions and Answers

1.

Insufficient centrifugation will result in:
- A.
  
  A false increase in Hct value
- B.
  
  A false decrease in Hct value
- C.
  
  No effect on Hct value
- D.
  
  All of the above depending on the patient
2.

Erythrocytes that vary in size from the normal 6-8 um are described as exhibiting:
- A.
  
  Anisocytosis
- B.
  
  Hypochromia
- C.
  
  Poikilocytosis
- D.
  
  Pleocytosis
3.

Which of the following is the preferable site for bone marrow aspiration and biopsy in an adult?
- A.
  
  Iliac crest
- B.
  
  Sternum
- C.
  
  Tibia
- D.
  
  Spinous processes of the vertebra
4.

Mean cell volume (MCV) is calculated using the following:
- A.
  
  (Hgb/RBC)x10
- B.
  
  (Hct/RBC)x10
- C.
  
  (Hct/Hgb)x100
- D.
  
  (Hgb/RBC)x100
5.

What term describes the change in shape of erythrocytes seen on a Wright's-stained peripheral blood smear:
- A.
  
  Poikilocytosis
- B.
  
  Anisocytosis
- C.
  
  Hypochromia
- D.
  
  Polychromasia
6.

Calculate the mean cell hemoglobin concentration (MCHC) using the following values: Hgb: 15 g/dL RBC: 4.50 x 10^6/uL Hct: 47 mL/dL
- A.
  
  9.5% (.095)
- B.
  
  10.4% (.104)
- C.
  
  31.9% (.319)
- D.
  
  33.3% (.333)
7.

A manual white blood cell count was performed. A total of 36 cells were counted in all 9-mm^2 squares of a Neubauer-ruled hemacytometer. A 1:10 dilution was used. White is the WBC?
- A.
  
  0.4x10^9/L
- B.
  
  2.5x10^9/L
- C.
  
  4.0x10^9/L
- D.
  
  8.0x10^9/L
8.

When an erythrocyte containing iron granules is stained with Prussian blue, the cell is called a:
- A.
  
  Spherocyte
- B.
  
  Leptocyte
- C.
  
  Schistocyte
- D.
  
  Siderocyte
9.

A 7.0 mL etheylenediaminetetraacetic acid (EDTA) tube is received in teh lab containing only 2.0 mL of blood. If the lab is using manual techniques, which of the following tests will most likely be erroneous?
- A.
  
  RBC count
- B.
  
  Hemoglobin
- C.
  
  Hct
- D.
  
  WBC count
10.

A 1:200 dilution of a patient sample was made and 336 red cells were counted in an area of 0.2 mm^2. What is the RBC count?
- A.
  
  1.68 x 10^12/L
- B.
  
  3.36 x 10^12/L
- C.
  
  4.47 x 10^12/L
- D.
  
  6.66 x 10^12/L
11.

What phagocytic cells produce lysozymes that are bacteriocidal?
- A.
  
  Eosinophils
- B.
  
  Lymphocytes
- C.
  
  Platelets
- D.
  
  Neutrophils
12.

If a patient has a retic count of 7% and a Hct of 20% what is the corrected retic count?
- A.
  
  1.4%
- B.
  
  3.1%
- C.
  
  3.5%
- D.
  
  14%
13.

A decreased osmotic fragility test would be associated with which of the following conditions?
- A.
  
  Sickle cell anemia
- B.
  
  Hereditary spherocytosis
- C.
  
  Hemolytic disease of the newborn
- D.
  
  Acquired hemolytic anemia
14.

What effect would using a buffer at pH 6.0 have on a Wright's-stained smear?
- A.
  
  Red cells would be stained too pink
- B.
  
  White cell cytoplasm would be stained too blue
- C.
  
  Red cells would be stained too blue
- D.
  
  Red cells would lyse on the slide
15.

Which of the following erythrocyte inclusions can be visualized with supravital stain but cannot be detected on a Wright's stained blood smear?
- A.
  
  Basophilic stippling
- B.
  
  Heinz bodies
- C.
  
  Howell Jolly bodies
- D.
  
  Siderotic granules
16.

A falsely elevated Hct is obtained. Which of the following calculated values will not be affected?
- A.
  
  MCV
- B.
  
  MCH
- C.
  
  MCHC
- D.
  
  Red cell distribution width (RDW)
17.

A Miller disk is an ocular device used to facilitate counting of:
- A.
  
  Platelets
- B.
  
  Reticulocytes
- C.
  
  Sickle cells
- D.
  
  Nucleated red blood cells
18.

RBC indices obtained on a patient are as follows: MCV: 88 um^3 MCH: 30 pg MCHC: 34% The RBC on the peripheral smear would appear:
- A.
  
  Microcytic, hypochromic
- B.
  
  Microcytic, normochromic
- C.
  
  Normocytic, normochromic
- D.
  
  Normocytic, hypochromic
19.

All of the following factors may influence the ESR except:
- A.
  
  Blood drawn in a sodium citrate tube
- B.
  
  Anisocytosis, poikilocytosis
- C.
  
  Plasma proteins
- D.
  
  Caliber of the tube
20.

What staining method is used most frequently to stain and count reticulocytes?
- A.
  
  Immunofluorescence
- B.
  
  Supravital staining
- C.
  
  Romanowsky staining
- D.
  
  Cytochemical staining
21.

The Coulter principle for counting cells is based upon the fact that:
- A.
  
  Isotonic solutions conduct electricity better than cells do
- B.
  
  Conductivity varies proportionally to the number of cells
- C.
  
  Cells conduct electricity better than saline does
- D.
  
  Isotonic solutions cannot conduct electricity
22.

A correction is necessary for WBC counts when nucleated RBC are seen on the peripheral smear because:
- A.
  
  The WBC count would be falsely lower
- B.
  
  The RBC count is too low
- C.
  
  Nucleated RBC's are counted as leukocytes
- D.
  
  Nucleated RBC's are confused with giant platelets
23.

Using a Coulter counter analyzer, an increased RDW should correlate with:
- A.
  
  Spherocytosis
- B.
  
  Anisocytosis
- C.
  
  Leukocytosis
- D.
  
  Presence fo NRBCs
24.

Given the following values, which set of red blood cell indicies suggests spherocytosis?
- A.
  
  MCV 76 um^3 MCH 19.9 pg MCHC 28%
- B.
  
  MCV 90 um^3 MCH 30.5 pg MCHC 32.5%
- C.
  
  MCV 80 um^3 MCH 36.5 pg MCHC 39%
- D.
  
  MCV 81 um^3 MCH 29 pg MCHC 34%
25.

Which of the following statistical terms reflects the best index of precision?
- A.
  
  Mean
- B.
  
  Median
- C.
  
  Coefficient of variation
- D.
  
  Standard deviation