Exam I Immunopharmacology

20 Questions | Total Attempts: 639

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Immune System Quizzes & Trivia

Questions and Answers
  • 1. 
    Which of the following are involved in both innate and acquired immune responses? 
    • A. 

      B cells

    • B. 

      T cells

    • C. 

      Macrophages

  • 2. 
    Select the true statementsfor IgG.  
    • A. 

      Most abundant and most potent antibody

    • B. 

      Allergic and antiparasitic activity

    • C. 

      Present in bodily secretions

    • D. 

      Roles of agglutination, precipitation, and opsonization

    • E. 

      Conferral of immunity to fetus

    • F. 

      Antibody dependent cell-mediated cytotoxicity

    • G. 

      Present on surface of B lymphocytes

    • H. 

      Present most places, including lymph, blood, csf, and peritoneal fluid

  • 3. 
    IgM is the first antibody produced, with elevated levels indicating recent infection.  
    • A. 

      True

    • B. 

      False

  • 4. 
    IgM is too large to cross the placenta and is therefore synthesized by the placenta for protection of the fetus.  
    • A. 

      True

    • B. 

      False

  • 5. 
    Which of the following classes of antibody have the best agglutination and complement activation activity?  
    • A. 

      IgG

    • B. 

      IgM

    • C. 

      IgA

    • D. 

      IgD

    • E. 

      IgE

  • 6. 
    What is the primary function of IgD? 
    • A. 

      Differentiation/maturation of B cells

    • B. 

      Bactericidal/antiviral

    • C. 

      Agglutination, precipitation, opsonization

  • 7. 
    Antibodies present in one of the following two forms: free in circulation or bound to some cell.  
    • A. 

      True

    • B. 

      False

  • 8. 
     B and T cells both originate in the bone marrow, but B cells develop in the thymus, whereas T cells differentiate in the fetal liver and adult bone marrow.
    • A. 

      True

    • B. 

      False

  • 9. 
     Where are T cells educated to differentiate between self and non-self? This differentiation comes in the form of a T Cell Receptor.
    • A. 

      Bone marrow

    • B. 

      Thymus

    • C. 

      Spleen

    • D. 

      Brain

  • 10. 
    The presence of a T Cell Receptor differentiates a T cell from a B cell. 
    • A. 

      True

    • B. 

      False

  • 11. 
     T Cell Receptors are rarely associated with CD3 Receptors on T Cells.
    • A. 

      True

    • B. 

      False

  • 12. 
    The vast majority of T Cells contain which version of T Cell Receptor?  
  • 13. 
    Antigens must be processed by antigen presenting cells to be recognized by T Cells.  
    • A. 

      True

    • B. 

      False

  • 14. 
    Antigen presenting cells are required to present antigens to T cells, but not B cells.  
    • A. 

      True

    • B. 

      False

  • 15. 
    B cells and T cells recognize antigens in much the same manner. 
    • A. 

      True

    • B. 

      False

  • 16. 
    Viral infection is the most potent natural signal for the synthesis of which of the following cytokines? 
    • A. 

      TNFa

    • B. 

      IL-18

    • C. 

      INFa+b

  • 17. 
     Type I Interferons, mediators of natural immunity, have which of the following as their principal biologic actions?
    • A. 

      Inhibition of viral replication

    • B. 

      Inhibition of cell proliferation

    • C. 

      Increasing lytic potential of natural killer cells

    • D. 

      Regulation of MHC I and II expression

  • 18. 
     TNFa responds primarily to which of the following?
    • A. 

      Viral Infection

    • B. 

      Gram-Negative Bacteria

    • C. 

      Gram-Positive Bacteria

    • D. 

      Tumor Growth

  • 19. 
     TNFa is most like which of the following interleukins?
    • A. 

      IL-1

    • B. 

      IL-2

    • C. 

      IL-6

    • D. 

      IL-18

  • 20. 
    Colony Stimulating Factors are commonly used for which of the following indications?  
    • A. 

      Prevention of chemotherapy-induced neutropenia

    • B. 

      Stimulation of haemopoiesis in marrow failure

    • C. 

      Promotion of cell differentiation

    • D. 

      Assisting marrow transplantation

    • E. 

      Augmentation of effector cell function

    • F. 

      Stimulation of monocyte's anticancer effects

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