Antigens And T Cells Quiz

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| By Luck2liv

Luck2liv

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Quizzes Created: 8 | Total Attempts: 4,655

Questions: 9 | Attempts: 800 | Updated: Mar 22, 2023

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T cells come in different forms there are those T-cells that hunt down and destroy cells that are infected with germs the other main type of T-cells are orchestrate an immune response. Antigens are any substance that stimulates the immune system to produce antibodies. Take up the quiz below and learn more about these.

Questions and Answers

1.

T cell receptors
- A.
  
  Can recognize any antigen
- B.
  
  Can only recognize peptide antigens bound to MHC molecules
- C.
  
  Are membrane-bound glycoproteins
- D.
  
  Have multiple antigen binding sites
- E.
  
  B and C only
Correct Answer
E. B and C only

Explanation
The correct answer is B and C only because T cell receptors can only recognize peptide antigens bound to MHC molecules and they are also membrane-bound glycoproteins. They cannot recognize any antigen and do not have multiple antigen binding sites.

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2
0
2.

This cell helps B cells convert to plasma cells:
- A.
  
  CD4TH1
- B.
  
  CD4TH2
- C.
  
  CD8
- D.
  
  Th17
- E.
  
  Treg
Correct Answer
B. CD4TH2

Explanation
CD4TH2 cells, also known as helper T cells type 2, play a crucial role in the immune response by assisting B cells in their transformation into plasma cells. These plasma cells are responsible for producing and secreting antibodies, which are essential for fighting off infections. CD4TH2 cells release specific chemical signals called cytokines that activate B cells, promote their proliferation, and enhance antibody production. Therefore, CD4TH2 cells are essential in the adaptive immune response and contribute to the body's ability to defend against pathogens.

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3.

Listeria monocytogenes, a classic intracellular bacterium, would most likely elicit:
- A.
  
  MHC-II antigen presentation and CD4Th2 cells
- B.
  
  MHC-II antigen presentation and CD4Th1 cells
- C.
  
  MHC-I antigen presentation and CD8
- D.
  
  Th17 and neutrophils
- E.
  
  Treg to attack infected T cells
Correct Answer
B. MHC-II antigen presentation and CD4Th1 cells

Explanation
Listeria monocytogenes is an intracellular bacterium, meaning it infects and replicates within host cells. MHC-II antigen presentation is involved in presenting antigens from extracellular pathogens, such as bacteria, to CD4 T helper cells. CD4Th1 cells are a subset of CD4 T cells that primarily respond to intracellular pathogens, including bacteria. Therefore, it is likely that Listeria monocytogenes infection would elicit MHC-II antigen presentation and CD4Th1 cells to mount an immune response against the bacterium.

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1
0
4.

B7 interacts with ___________

Correct Answer
CD28
cd28

Explanation
B7 interacts with CD28 and cd28. CD28 is a protein receptor found on the surface of T cells, and it plays a crucial role in T cell activation. B7, also known as B7-1 and B7-2, is a protein ligand found on the surface of antigen-presenting cells. When CD28 on T cells binds to B7 on antigen-presenting cells, it provides a co-stimulatory signal that enhances T cell activation and proliferation. This interaction is important for the initiation of an effective immune response against pathogens.

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4
5.

Cyclosporin blocks the production of ____________ and hence the expansion of T cells.

Correct Answer
IL-2
IL2
il2

Explanation
Cyclosporin is a medication that inhibits the production of IL-2, also known as IL2 or il2. IL-2 is a cytokine that plays a crucial role in the expansion and activation of T cells. By blocking the production of IL-2, Cyclosporin effectively prevents the proliferation of T cells, which is beneficial in conditions where an overactive immune response, such as in organ transplantation or autoimmune diseases, needs to be controlled.

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4
6.

A toxin that forms a bridge between CD4 T cell receptors and MHC class II molecules causing T cells to divide and differentiate are called:
- A.
  
  B7 mimicers
- B.
  
  Exotoxin
- C.
  
  Cephalosporin
- D.
  
  Superantigen
- E.
  
  Superbug
Correct Answer
D. Superantigen

Explanation
Superantigens are toxins that can bind simultaneously to the T cell receptor (TCR) and major histocompatibility complex class II (MHC II) molecules, forming a bridge between them. This interaction leads to the activation of a large number of T cells, causing them to divide and differentiate. Therefore, superantigens are responsible for the excessive activation of the immune system, leading to harmful effects such as inflammation and tissue damage.

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7.

A T cell receptor
- A.
  
  Can undergo somatic recombination
- B.
  
  Class switch
- C.
  
  Can undergo somatic hypermutation
- D.
  
  Be cleaved to produce an Fc fragment
- E.
  
  Secrete either Th2 or Th1 cells
Correct Answer
A. Can undergo somatic recombination

Explanation
The correct answer is "can undergo somatic recombination." Somatic recombination is a process that occurs during T cell development, where gene segments encoding the variable regions of the T cell receptor (TCR) are rearranged to generate a diverse repertoire of TCRs. This allows T cells to recognize a wide range of antigens. Somatic recombination is a crucial mechanism for generating T cell diversity and is unique to T cells.

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8.

Three professional antigen presenting cells are
- A.
  
  Dendritic cells, macrophages, and neutrophils
- B.
  
  Dendritic cells, macrophages, and T cells
- C.
  
  Dendritic cells, macrophages, and B cells
- D.
  
  Neutrophils, eosinophils, and mast cells
- E.
  
  Natural killer cells, fibroblasts, and dendritic cells
Correct Answer
C. Dendritic cells, macrophages, and B cells

Explanation
Dendritic cells, macrophages, and B cells are professional antigen presenting cells. Dendritic cells are specialized in capturing and presenting antigens to activate T cells. Macrophages are responsible for engulfing and digesting pathogens, and then presenting the antigens on their surface to activate immune responses. B cells, on the other hand, are involved in the production of antibodies and can also present antigens to T cells. Together, these three cell types play a crucial role in initiating and coordinating immune responses against pathogens.

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9.

A ssRNA virus will activate:
- A.
  
  TLR 3 and TLR 10
- B.
  
  TLR 3 and TLR 7
- C.
  
  TLR 2 and TLR 4
- D.
  
  TLR 3 and TLR 4
- E.
  
  B7 and CD28
Correct Answer
B. TLR 3 and TLR 7

Explanation
ssRNA viruses are recognized by Toll-like receptor 3 (TLR 3) and Toll-like receptor 7 (TLR 7). These receptors are part of the innate immune system and are responsible for detecting viral nucleic acids. TLR 3 specifically recognizes double-stranded RNA, while TLR 7 recognizes single-stranded RNA. Therefore, when a ssRNA virus infects a host, it activates both TLR 3 and TLR 7 to initiate an immune response against the virus. The other options mentioned in the question (TLR 2 and TLR 4, B7 and CD28) are not involved in the recognition of ssRNA viruses.

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Antigens And T Cells Quiz

T cell receptors

This cell helps B cells convert to plasma cells:

Listeria monocytogenes, a classic intracellular bacterium, would most likely elicit:

B7 interacts with ___________

Cyclosporin blocks the production of ____________ and hence the expansion of T cells.

A toxin that forms a bridge between CD4 T cell receptors and MHC class II molecules causing T cells to divide and differentiate are called:

A T cell receptor

Three professional antigen presenting cells are

A ssRNA virus will activate: