CRISPR in the hands of a single researcher is powerful. CRISPR embedded in a gene drive is...
A double-strand break created by Cas9 is just the beginning. What the cell does next deter...
Once guided to its target by the gRNA, Cas9 does something elegant and precise: it cuts bo...
Hidden inside bacterial genomes for billions of years was a sophisticated adaptive immune ...
Before Cas9 can cut anything, it needs directions, and those directions come in the form o...
Sometimes the goal of gene therapy is not to add a functional gene but to silence a harmfu...
Some of the most devastating genetic diseases are caused by mutations in a single gene, wh...
A gene therapy that corrects a mutation in the liver of a patient affects only that patien...
Gene therapy does not always happen inside the patient's body. Sometimes the most effe...