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Advanced Quiz on Human Reproductive Anatomy and Embryological Genetics

Explore the intricate world of reproductive anatomy and embryology. This focused assessment tests knowledge on developmental stages, anatomical structures, and reproductive functions, essential for students and professionals in...

Questions: 28 | Attempts: 10 | Last updated: Aug 4, 2025

Sample Question 1
What is the function of the Sonic hedgehog gene and where is it located?

Sonic hedgehog gene is responsible for coding structural proteins in muscles.

Sonic hedgehog gene is involved in regulating blood sugar levels in the body.

Sonic hedgehog gene functions in the synthesis of digestive enzymes in the pancreas.

*Sonic hedgehog gene is involved in proper development of CNS/in Patterning of ANTERIO- POSTERIOR axis, it is expressed at the base of the limbs in zone of polarizing activity....do NOT confuse this with Wnt-7 gene which is expressed on Most distal part of DISTAL Limbs(APICAL ECTODERMAL ridge), note that This gene is involved in patterning VENTRAL-DORSAL Axis at the DISTAL Limb..Once again fo Sonic hedehog gene it is HY to know that it is responisble for CHAPERONING of directional growth of CNS and defects have been implicated in HOLOPROSONCEPHALY in PATAU syndrome.

Sample Question 2
Mutation in gene produced at APICAL ECTOdermal ridge that stimulates MITOSIS of Underlying mesoderm....How this could help you understand HY disorder from MSK section?

The mutated gene leads to changes in eye color

The gene is responsible for hair growth regulation

*Gene produced APICAL ECTOdermal ridge that stimulates MITOSIS of Underlying mesoderm is involved in LENGTHENING of the LIMBS and is known as FGF gene(Thus FGF promotes growth of Limbs trough stimulation of PROLIFERATION<Has been tested)...remember that FGF RECEPTOR3(FGFR3) is involved in development of ACHONDROPLASIA where trunk/head size is normal but growth of LONG TUBULAR BONES/LIMBS Is defective due to defective ENDOCHONDRIAL ossification..

Mutation in the gene causes muscle atrophy in the limbs

Sample Question 3
What does a mutation in the HOMEBOX (HOX) genes likely code for and what is its function in relation to Polysyndactyly and appendages in wrong locations?

B. Hormones that regulate growth and development.

A. Enzymes responsible for protein synthesis and cell division.

C. Structural proteins found in bones and muscles.

*Knowing that Polysyndactyly/appendages in wrong places=mutation in HOMEBOX (HOX)genes is not enough, they often test the fact that this gene codes for DNA Binding Transcription regulators...they can also potentially ask its function so know that it is involved in SEGMENTAL organization of fetus in CRANIOCAUDAL direction....

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