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  • Which of the following is true regarding loop diuretics?
    Which of the following is true regarding loop diuretics?
    All the options listed above are correct. Loop diuretics are sulfa containing drugs that Inhibit cotransport system (Na+/K+/2Cl−) of thick ascending limb of loop of Henle. Patients that are allergic to sulfa drugs may develop allergy with the use of loop diuretics. They may cause hypokalemia and hypomagnesmia in patients taking them. NSAID inhibits loop diuretics which in turn diminish the effect of the diuretics. Loop diuretics increase sensitivity to the sun, patient may need to wear sunscreen while taking the medication. Foods also decrease the bioavailability of loop diuretics.

  • Which parameters are necessary for T.R.?
    Which parameters are necessary for T.R.?
    Quarterly serum C-peptide levelThe A1C and SMBG tests are essential for monitoring the success of glucose control therapy. The SMBG gives an immediate determination of BG level and the A1C gives an average reading over the previous 2-3 months (or 120 days, the life span of a RBC). Phenytoin levels are necessary for monitoring therapeutically appropriate levels, and BP readings are for monitoring success of antihypertensive therapy. A serum C-peptide might be diagnostic for the determination of functioning beta-cells; however, if performed, it is done very infrequently to reduce cost.

  • Which order is the optimal antithrombotic therapy for this patient? A 64-year-old female with a past medical history of hypertension and diabetes is receiving enalapril, chlorthalidone, and...
    Which order is the optimal antithrombotic therapy for this patient? A 64-year-old female with a past medical history of hypertension and diabetes is receiving enalapril, chlorthalidone, and...
    Warfarin titrated to an INR 2.0–3.0EXPLANATION: This patient has a CHADS2 score of2 (hypertension and diabetes) so warfarin titrated to an INR of2.03.0 is the treatment of choice if there are no contraindicationsto warfarin.

  • Which oral antidiabetic agent is a micronized formulation?
    Which oral antidiabetic agent is a micronized formulation?
    GlynaseGlynase is a micronized formulation of glyburide that is significantly absorbed (e.g., a 3-mg tablet provides blood levels similar to a 5-mg conventional tablet). Micronase is a trade name for non-micronized glyburide. Glucotrol XL is the name of an extended formulation of glipizide. Orinase is the trade name for tolbutamide (the only first-generation sulfonylurea listed here) and Amaryl is the trade name for glimepiride.

  • Which of the following is not true for acarbose therapy?
    Which of the following is not true for acarbose therapy?
    Hypoglycemia due to combination therapy should be treated with sucroseOral glucose instead of carbohydrate sources with sucrose (cane sugar) or fructose is used because absorption of these is inhibited. The remaining items are true of acarbose therapy.

  • Which of the following best describes the site and mechanism of action of acarbose in diabetes?
    Which of the following best describes the site and mechanism of action of acarbose in diabetes?
    Within the intestine to impair carbohydrate absorption

  • If a pt is considered "warm and wet", this means.
    If a pt is considered "warm and wet", this means.
    The pt has adequate perfusion but s/s of volume overload.About 70% of pts are assigned to the warm and wet classification.

  • Which of the following are true regarding ACE inhibitors?
    Which of the following are true regarding ACE inhibitors?
    ACEIs reduce mortality by 20-30% and slow the progression of HF Captopril should be taken on an empty stomach, either 1 hour before or 2 hours after meals Cyclosporine and tacrolimus may increase the risk of nephrotoxicity and hyperkalemiaAdditional potassium should be used cautiously (not encouraged). ACEIs are pregnancy category C during the 1st trimester and pregnancy category D during the second and third trimesters.

  • Which of the following is a false counseling point for a patient taking beta blockers for heart failure.
    Which of the following is a false counseling point for a patient taking beta blockers for heart failure.
    None - all of the above are true counseling points

  • Which of the following are true regarding heart failure?
    Which of the following are true regarding heart failure?
    Verapamil and diltiazem can precipitate or worsen heart failure Headache, dizziness, and GI complaints are common adverse effects with hydralazine-isosorbide dinitrate No loading dose of digoxin is needed in HF; in fact, lower doses (0.125mg QOD) may need to be used in the elderlyDigoxin - 0.5 - 1 Pts with ADHF often require POSITIVE inotropes (dopamine, dobutamine, milrinone)

  • A patient with hypretnsion, CAD, or diabetes would fit into what heart failure classification scheme according to the American College of Cardiology and the American Heart Association?This...
    A patient with hypretnsion, CAD, or diabetes would fit into what heart failure classification scheme according to the American College of Cardiology and the American Heart Association?This...
    Stage AStage A includes pts at high risk of developing heart failure, but without presence of sx that are strongly associated with heart failure. According to this classifcation, neither pts in Stage A or B actually have heart failure.

  • Which of the following diabetes medications can be dosed in a manner to selectively lower postprandial glucose?I. MetforminII. Acarbose III. Pioglitazone IV. Nateglinide V. Insulin glulisine...
    Which of the following diabetes medications can be dosed in a manner to selectively lower postprandial glucose?I. MetforminII. Acarbose III. Pioglitazone IV. Nateglinide V. Insulin glulisine...
    II, IV, and VAcarbose, nateglinide, and insulin glulisine all have pharmacokinetic profiles that make them suitable for postprandial coverage. Nateglinide peaks in 1 hour and has a duration of 4 hours. Acarbose has a duration of 13 hours. Glulisine has an onset of 1530 minutes, peaks in 3090 minutes, and has a duration of 13 hours.

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