Histones - High Yield Topic Series
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Anti histone antibodies are seen in
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Drug induced lupus
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SLE
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Primary biliary Cirrhosis
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Dermatomyositis
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Explore the role of histones in gene regulation with our 'Histones - High Yield Topic Series'. This quiz covers anti-histone antibodies in drug-induced lupus, histone acetylation, and unique mRNA structures in histones. Ideal for students and professionals enhancing their understanding of DNA and genetics.
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- 2.
Histone acetylation leads to
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Euchromatin
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Heterochromatin
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Both of the above
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None of the above
Correct Answer
A. EuchromatinExplanation
Histone acetylation refers to the process of adding acetyl groups to histone proteins, which are involved in DNA packaging. This modification loosens the structure of chromatin, allowing for easier access to DNA and promoting gene expression. Euchromatin is a less condensed form of chromatin that is actively transcribed, while heterochromatin is a highly condensed form that is transcriptionally inactive. Therefore, histone acetylation leads to euchromatin formation, making the correct answer "Euchromatin".Rate this question:
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- 3.
Poly A tail is usually present in 3' end of all pre-mRNA. But it is not present in the pre-mRNA of histone.
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True
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False
Correct Answer
A. TrueExplanation
The poly A tail is a sequence of adenine nucleotides that is usually added to the 3' end of pre-mRNA molecules during RNA processing. However, in the case of histone pre-mRNA, this poly A tail is not present. This is because histone genes have a different mechanism of mRNA processing that involves cleavage and polyadenylation at a specific site within the coding region, rather than at the 3' end. Therefore, the statement that the poly A tail is not present in the pre-mRNA of histone is true.Rate this question:
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- 4.
Instead of poly A tail, which structure is present in the 3' end of the pre-mRNA of histone ?
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Stem loop
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Zinc finger
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Leucine zipper
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None of the above
Correct Answer
A. Stem loopExplanation
In the 3' end of the pre-mRNA of histone, a structure called a stem loop is present instead of a poly A tail. A stem loop is a secondary structure formed when a sequence of nucleotides in the mRNA folds back on itself, creating a stem and a loop. This structure is important for the stability and regulation of the mRNA molecule.Rate this question:
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- 5.
Select the wrong statement ?
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Histone methylation is in general associated with transcriptional repression
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Histone acetylation tends to destabilize chromatin structure
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Histone is rich in basic amino acids.
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H1 is a component of Histone octamer.
Correct Answer
A. H1 is a component of Histone octamer.Explanation
H1 histone is a linker.Rate this question:
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Oct 25, 2023Quiz Edited by
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May 07, 2012Quiz Created by
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