Neurology is the branch of medicine concerned with the study and treatment of disorders of the nervous system. The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It has two major divisions: Central nervous system: the brain and spinal cord.
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60%
20%
75%
45%
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Amacrine > ganglion > bipolar > photorecepotors
Ganglion > amacrine > bipolar > horizontal
Amacrine > ganglion > horizontal > photoreceptors
Amacrine > bipolar > ganglion > photoreceptors
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L cones
M cone
S cone
Rods
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2, 5, 1, 3, 4, 6
1, 2, 3, 4, 5, 6
3, 2, 1, 4, 6, 5
2, 5, 3, 1, 4, 6
50
25
80
75
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High [Na+]
low [Na+]
High [K+]
Low [K+]
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Cilium consists of 9 double microtubules that aid in the transportation of ions and newly made proteins
Ciulium consists of 9 double microfilaments that aid in the transportation of ions and newly made proteins
Cilium consists of 9 double microtubules that aid in the removal of discs at the end of their life cycle
The cilium is a performs motor function to aid the photoreceptor in motility
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Cone inner segment diameter increases with increasing eccentricity
You would find no cones in the periphery
Rods increase in population eccentrically
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Muller's cells
Oligodendrocytes
Type I astrocyte
Type II astrocyte
Type III astrocyte
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Oligodendrocytes
Astrocytes
Photoreceptors
Muller cells
Ganglion cells
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Help hold blood vessels in place
Control blood flow out of vessels
Form the blood brain barrier
Provide myelination to RGC axons
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Allows rods to have an expanded range of response capabilities under different lighting conditions
Allows rods to have one uniform response to all light levels
Allows for cones to have isolated pathways without input from rods
I dont know, they just do!
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Rod --> rod ON bipolar cell --> A2 amacrine cell --> cone ON bipolar cell --> On ganglion cell
Rod --> rod bipolar cell --> A2 amacrine cell ---> cone OFF gc via glycine synapse
Rod ---> cone (gap junction) ---> on and off bipolar cell ---> on and off ganglion cell
Rod --> off cone bipolar cell --> off cone ganglion cell
Rod ---> OFF rod bipolar cell --> A2 amacrine cell --> OFF rod ganglion cell
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Horizontal cell bodies
Photoreceptor cell bodies
Amacrine cell bodies
Interplexiform cell bodies
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H1
H2
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Biplexiform-GC
Alpha-GC
Beta-GC
Gamma-GC
ON - rod ganglion cell
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Horizontal cells
Ganglion cells
Photoreceptors
Bipolar cells
Biplexiform cell s
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50%
25%
33%
90%
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Interplexiform neurons
Ganglion cells
Amacrine cells
Horizontal cells
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Increased receptive field size
Decreased receptive field size
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29
14
20
24
19
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Horizontal cell <--> midget bipolar cell
Horizontal cell <--> Horizontal cell
Cone <--> midget bipolar cell
Cone<--> flate bipolar cell
Synaptic lamellae
Arciform density
Arciform lamellae
Synaptic density
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2
1
3
None rods don't have spherules
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3 gap junctions
2 tight junctions
1 gap junction
1 tight junction
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1 ganglion cell, 1 amacrine cell, 1 bipolar cell
2 amacrine cells, 1 bipolar cell
2 bipolar cells, 1 ganglion cell
1 horizontal cell, 1 bipolar cell, 1 ganglion cell.
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Alpha- GC > Gamma GC > Beta GC
Alpha GC > Beta GC > Gamma GC
Gamma GC > Beta GC > Alpha GC
Beta GC > Gamma GC > Alpha GC
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Alpha and Beta
Alpha and Gamma
Beta and Gamma
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Amacrine cell
Ganglion cells
Phtoreceptor
Bipolar cells
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-20mV
-60mV
+20mV
-70mV
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-60mV
+40mV
-20mV
-40mV
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Rhodopsin ---> bathorhodopsin
Rhodopsin ---> Opsin + all-trans retinAL
Rhodopsin ---> 11-cis retinAL
Rhodopsin ---> all-trans retinol
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Photoreceptors
OFF bipolar cells
Horizontal cells
Ganglion cells
Amacrine cells
ON bipolar cells
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Biplexiform cell
Amacrine cell
Ganglion cell
Horizontal cell
Photoreceptor cell
Bipolar cell
It applies to all cells in the retina
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Sub-optimal response
Maximal response
Minimal response
No response
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Visual acuity
Pupillary response
Cortical flicker fusion frequency
Extraocular motility
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W cells
X-cells
Beta-cells
Y-cells
Alpha cells
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W < X < Y
Y < X < W
X < Y < W
Y < W < X
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P beta
P alpha
Y cells
W cells
Magnocellular cells
Parasol cells
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90%
100%
80%
10%
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1
2
3
4
5
6
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Left LGN areas 1, 4, & 6
Right LGN, areas 1,4 & 6
Left LGN, areas 2, 3, & 5
Left LGN, areas 2, 3, & 5
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Vertical midline
Inferior
Macula
Superior
Lateral
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20
10
1
60
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Fewest of the parvocellular cells
Color opponent organization without a center surround
Center surround organization with simple color opponent organization
Smallest receptive field
Most of the parvocellular cells
Achromatic
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Parvo type 1
Parvo type 2
Parvo type 3
Parvo type 4
Magno type 1
Magno type 2
Magno type 3
Magno type 4
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Parvo type 1
Parvo type 2
Parvo type 3
Magno type 3
Magno type 4
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