Pharmacology Chapter 20/ Cholinergic Drugs

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Pharmacology Chapter 20/ Cholinergic Drugs - Quiz

In today’s quiz about the topic of pharmacology – the branch of medicine that concerns itself with drugs – we’ll be looking at cholinergic drugs, which are relative to nerve cells in which acetylcholine acts as a neurotransmitter. What do you know?


Questions and Answers
  • 1. 
    The neurotransmitter responsible for transmission of nerve impulses to effector cells in the parasymapthetic nervous system.
  • 2. 
    Lack of normal muscle tone
  • 3. 
    Which of the following are are a class of drugs that stimulate the parasympathetic nervous system.
    • A. 

      Sympathomimetics

    • B. 

      Parasympathomimetics

    • C. 

      Cholinergic drugs

    • D. 

      Cholinergic agonists

    • E. 

      Sympothylotics

  • 4. 
    A __________ receptor binds actetylcholine and mediates its acitons.
  • 5. 
    ________- acting drugs work by inhibiting the action of acetylcholinesterase
  • 6. 
    Muscarinic receptors are stimulated by ________, a substance isolated from mushrooms.
    • A. 

      Muscarine

    • B. 

      Acetylcholine

    • C. 

      Dopamine

    • D. 

      Nicotine

  • 7. 
    Indirect acting cholinergic drugs are also know as cholinesterase ________
  • 8. 
    When acetylcholine directly binds to its receptor, _______ occurs.
  • 9. 
    Cholinergic drugs ___________ the intestine and bladder, which results in _________ gastric secretions, GI motility, and urinary ________.
    • A. 

      Stimulate, increased, frequency

    • B. 

      Inhibit, decreased, retention

    • C. 

      Stimulate, decreased, frequency

    • D. 

      Inhibit, increased, retention

  • 10. 
    Constriction of the pupil.
  • 11. 
    Which of the following is an effect of cholinergic drugs.
    • A. 

      Increased salivation and sweating

    • B. 

      Reduced heart rate and vasodilation

    • C. 

      Constriction of the bronchi in the lungs and narrowing of airways

    • D. 

      Stimulation of the intestine and bladder.

    • E. 

      Mydriasis

    • F. 

      Decreased salivation and sweating

  • 12. 
    Which cholinergic receptors are stimulated with high dosages of cholinergic drugs and cause many of the undesirable effects.
  • 13. 
    Oral direct acting drug that is used to treat atony of the bladder and GI tract.
    • A. 

      Bethanechol

    • B. 

      Carbachol

    • C. 

      Donepezil

    • D. 

      Physostigmine

  • 14. 
    The following are indications for use of indirect-acting cholinergic drugs.
    • A. 

      Myasthenia gravis

    • B. 

      Antidote for anticholinergic poisoning

    • C. 

      Alzheimers disease

    • D. 

      Atony of the bladder and GI tract

    • E. 

      Reduction of intraocular pressure in patient's with glaucoma

  • 15. 
    Which of the following are cardiovascular adverse effects of cholinergenic drugs
    • A. 

      Bradycardia

    • B. 

      Tachycardia

    • C. 

      Hypotension

    • D. 

      Hypertension

    • E. 

      Syncope

    • F. 

      Conduction abnormalities

  • 16. 
    Which of the following are CNS adverse effects of cholinergic drugs
    • A. 

      Headaches

    • B. 

      Dizziness

    • C. 

      Convulsions

    • D. 

      Ataxia

    • E. 

      Depression

    • F. 

      Anxiety

  • 17. 
    Which of the following are GI adverse effects of cholinergic drugs
    • A. 

      Abdominal cramps

    • B. 

      Increased secretions

    • C. 

      Nausea and vomiting

    • D. 

      Constipation

    • E. 

      Diarrhea

    • F. 

      Anorexia

  • 18. 
    Which of the following are respiratory adverse effects of cholinergic drugs
    • A. 

      Increased bronchial secretions

    • B. 

      Bronchospasm

    • C. 

      Cough

    • D. 

      Dyspnea

    • E. 

      Bronchitis

  • 19. 
    Which of the following miscellaneous adverse effects of cholinergic drugs
    • A. 

      Lacrimation

    • B. 

      Sweating

    • C. 

      Salivation

    • D. 

      Miosis

    • E. 

      Mydriasis

    • F. 

      Dehydration

  • 20. 
    Contraindications for cholinergic drugs include
    • A. 

      GI or GU tract obstruction

    • B. 

      Bradycardia

    • C. 

      Hyperthyroidism

    • D. 

      Epilepsy

    • E. 

      Hypotension

    • F. 

      COPD

    • G. 

      Alzheimers disease

    • H. 

      Glaucoma

  • 21. 
    Antidote for cholinergic drugs
  • 22. 
    What does SLUDGE stand for?
  • 23. 
    What is the acronym for the effects of a cholinergic crises?
  • 24. 
    Which of the following drugs may antagonize the use of cholinergic drugs?
    • A. 

      Anticholinergics

    • B. 

      Antihistamines

    • C. 

      Sympathomimetics

    • D. 

      Sympalyotics

    • E. 

      MAOIs

  • 25. 
    The nurse is reviewing the use of bethanechol in a patient who is experiencing postoperative urinary retention. Which statement best describes the mechanism of action of bethanechol?
    • A. 

      It caused decreased bladder tone and motility

    • B. 

      It causes increased bladder tone and motility

    • C. 

      It increases the sensation of a full bladder

    • D. 

      In causes the sphincters in the bladder to become tighter

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