Pharm practice quiz 4 assesses knowledge on antiemetics, focusing on their receptors, mechanisms of action, and specific effects. It evaluates understanding of drugs used for nausea and vomiting, enhancing learner's ability to identify appropriate treatments.
PPIS should be taken 30-60 minutes before a meal.
PPIs should be chewed or crushed to promote absorption
PPIs are used to treat erosive esophagitis
Duration of therapy for a gastric ulcer is 4-8 weeks
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Nizatidine
Bismuth
Esomeprazole
Cimetidine
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Metronidazole
Mesalamine
Misoprostol
Methotrexate
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Lamivudine
Sulfasalazine
Mesalamine
Olsalazine
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Lansoprazole
Omeprazole
Rabeprazole
Pantoprazole
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Breast feeding
Yeast hypersensitivty
Immunosuppression
These are all contraindications
None of these are contraindications
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Cannabinoids
Anticholinergics
Phenothiazines
Benzodiazepines
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Treatment for IBD with corticosteroids is at a dosage of 40-60mg daily.
The hydrocortisone enema is more effective than the foam or the suppository
The foam provides greater systemic absorption than the enema
These are all true
These are all false
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Parkinson's disease
Pregnancy
Active liver disease
Severe renal impairment
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Loperamide
Diphenoxylate/atropine sulfate
Bismuth subsalicylate
Attapulgite
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Chronic diarrhea
Constipation
Traveler's diarrhea
Anticipatory nausea
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Psyllium
Polycarbophil
Lactulose
Methylcellulose
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Inhibition of serotonin receptors in the vomiting center
Direct dopamine antagonism at the chemoreceptor trigger zone
Inhibition of dopamine receptors in the gastrointestinal tract and chemoreceptor trigger zone
Inhibition of cholinergic receptors, which decreases stimulation of the vomiting center
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Benzodiazepines
Dexamethasone
Phenothiazines
Serotonin antagonists
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Decrease in thromboxane
Inhibition of cox-1
Inhibition of cox-2
Decrease in arachidonic acid
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It binds with food in the stomach to form a paste-like substance that promotes healing
It reduces stomach acid
It reacts with hydrochloric acid in the stomach and binds to the surface of the ulcer
It inhibits the secretion of H+ ions from parietal cells in the stomach
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Uremic bleeding
Hyperphosphatemia
Potassium imbalance
Osteodystrophy
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Polycarbophil
Bismuth subsalicyclate
Loperamide
Fiber supplements
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Milk of magnesia
Prune juice
ExLax
Sorbitol
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CrCl = [(140-age) x weight in kg]/(72 x Scr
If a patient is obese, calculate adjusted body weight if body weight is greater than 10% over ideal body weight
Male ideal body weight = 50kg + 2.3 kg/inch > 5 feet
Adjusted body weight = ideal body weight + 0.4(actual - ideal)
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Havrix - hepatitis A
Recombivax - hepatitis B
Vaqta - hepatitis B
Engerix B - hepatitis B
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100 daltons
300 daltonsu
500 daltons
700 daltons
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Cannabinoids
Benzodiazepines
Corticosteroids
Anticholinergics
Benzamides
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Peripheral hypotension
Volume overload
Stevens-Johnson syndrome
Seizures
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Butyrophenones
Phenothiazines
Cannabinoids
Antihistamines
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Antacids
H2 antagonists
PPIs
Sucralfate
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Methotrexate
Cyclosporine
Azathioprine
Infliximab
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Reduce leukotriene production and inhibit bacteria-induced chemotaxis
Reduce infiltration of inflammatory cells and TNF
Binds to cyclophilin receptor, inhibiting T cell activation
Augment the immune system and enhance phagocytosis
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Renal dysfunction
Recumbent patients
Use simultaneously with psyllium
Flatulence
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It is not used
It increases LES tone
It decreases peristalsis
It is the only medicine safe to use in patients on MAOIs
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Lactulose
Non-selective beta blocker
Calcium channel blocker
Mannitol
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Phenothiazines
Serotonin (5-HT3) antagonists
Butyrophenones
Benzamides
None of the above
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Platelets at 52,000
Serious mood changes
Daily nausea with occasional vomiting
Fatigue
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Genotype 1
Genotype 2
Genotype 3
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Albumin
Blood
Dextrose
Lactated ringers
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12-16 weeks
3-6 months
2-3 days if given by IV
It takes effect immediately
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Week 0, 2, 6 and maintenance every 8 weeks
Week 0, 1, 3, 5 and maintenance every 4 weeks
Week 0, 3, 6, 9 and maintenance every 6 weeks
Every 8 weeks
High doses of methotrexate
NSAIDs
Tumor lysis syndrome
IV phosphate and calcium given together
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They are used for ulcerative colitis only
Microorganisms are not proven to be associated with disease progression in IBD
Ciprofloxacin, metronidazole, rifaxamin and ceftriaxone are commonly used
Antibiotics are not recommended for fistulas
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Daily vomiting
Platelets under 40,000
Fatigue severe enough to require bed rest
Serious mood changes
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Lamivudine (Epivir)
Entecavir (Baraclude)
Adefovir (Hepsera)
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6 weeks
12 weeks
24 weeks
48 weeks
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Furosemide
Metolazone
Dopamine
Fenoldepam
Mannitol
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Calcitriol
Calcium gluconate
Insulin/dextrose
Kayexalate
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Prednisone
Hydrocortisone
Azathioprine
Budesonide
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Infliximab
Adalimumab
Natalizumab
Cyclosporine
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Supportive care
Liver transplant
Interferons
Nucleoside analogs
All of the above
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Lansoprazole, clarithromycin, amoxicillin (Tritec)
Bismuth, metronidazole, tetracycline (Helidac)
Esomeprazole, clarithromycin, amoxicillin
Rabeprazole, clarithromycin, amoxicillin
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