Pharm Practice Quiz 4

53 Questions | Total Attempts: 1701

SettingsSettingsSettings
Please wait...
Pharm Practice Quiz 4

N/V/D, constipation, PUD, GERD, IBD, hepatitis, cirrhosis


Questions and Answers
  • 1. 
    Which of the following receptors is not involved in nausea and vomiting?
    • A. 

      Dopamine

    • B. 

      Acetylcholine

    • C. 

      Histamine

    • D. 

      Serotonin

    • E. 

      All of these are involved

  • 2. 
    Which of the following first-line antiemetics does not cause extrapyramidal symptoms?
    • A. 

      Phenothiazines

    • B. 

      Serotonin (5-HT3) antagonists

    • C. 

      Butyrophenones

    • D. 

      Benzamides

    • E. 

      None of the above

  • 3. 
    What is the MOA of benzamides?
    • A. 

      Inhibition of serotonin receptors in the vomiting center

    • B. 

      Direct dopamine antagonism at the chemoreceptor trigger zone

    • C. 

      Inhibition of dopamine receptors in the gastrointestinal tract and chemoreceptor trigger zone

    • D. 

      Inhibition of cholinergic receptors, which decreases stimulation of the vomiting center

  • 4. 
    Which of the following is used for anticipatory nausea?
    • A. 

      Cannabinoids

    • B. 

      Benzodiazepines

    • C. 

      Corticosteroids

    • D. 

      Anticholinergics

    • E. 

      Benzamides

  • 5. 
    Which of the following affects GABA receptors?
    • A. 

      Cannabinoids

    • B. 

      Anticholinergics

    • C. 

      Phenothiazines

    • D. 

      Benzodiazepines

  • 6. 
    Which of these antiemetic drugs do not cause blurred vision?
    • A. 

      Butyrophenones

    • B. 

      Phenothiazines

    • C. 

      Cannabinoids

    • D. 

      Antihistamines

  • 7. 
    Which of the following iss indicated for severe nausea and vomiting?
    • A. 

      Benzodiazepines

    • B. 

      Dexamethasone

    • C. 

      Phenothiazines

    • D. 

      Serotonin antagonists

  • 8. 
    Which antidiarrheal agent agent is only available by prescription?
    • A. 

      Loperamide

    • B. 

      Diphenoxylate/atropine sulfate

    • C. 

      Bismuth subsalicylate

    • D. 

      Attapulgite

  • 9. 
    Which drug should be used cautiously in infectious diarrhea?
    • A. 

      Polycarbophil

    • B. 

      Bismuth subsalicyclate

    • C. 

      Loperamide

    • D. 

      Fiber supplements

  • 10. 
    What is the main use for bismuth subsalicylate?
    • A. 

      Chronic diarrhea

    • B. 

      Constipation

    • C. 

      Traveler's diarrhea

    • D. 

      Anticipatory nausea

  • 11. 
    Which of the following is not a bulk-forming laxative?
    • A. 

      Psyllium

    • B. 

      Polycarbophil

    • C. 

      Lactulose

    • D. 

      Methylcellulose

  • 12. 
    Which is a contraindication of lubricant laxative use?
    • A. 

      Renal dysfunction

    • B. 

      Recumbent patients

    • C. 

      Use simultaneously with psyllium

    • D. 

      Flatulence

  • 13. 
    Which drug is metabolized to solutes in the GI tract, which moves water osmotically and facilitates propulsion and evacuation?
    • A. 

      Milk of magnesia

    • B. 

      Prune juice

    • C. 

      ExLax

    • D. 

      Sorbitol

  • 14. 
    Which would not cause problems?
    • A. 

      Colace and mineral oil

    • B. 

      Mineral oil and vitamin K

    • C. 

      Milk of magnesia in a patient with renal dysfunction

    • D. 

      Methylcellulose and mineral oil

  • 15. 
    Which is first line treatment for chronic mild to moderate GERD?
    • A. 

      Antacids

    • B. 

      H2 antagonists

    • C. 

      PPIs

    • D. 

      Sucralfate

  • 16. 
    Which of the following properties of NSAIDs contributes to formation of ulcers?
    • A. 

      Decrease in thromboxane

    • B. 

      Inhibition of cox-1

    • C. 

      Inhibition of cox-2

    • D. 

      Decrease in arachidonic acid

  • 17. 
    Which drug can prevent formation of NSAID induced ulcers?
    • A. 

      Metronidazole

    • B. 

      Mesalamine

    • C. 

      Misoprostol

    • D. 

      Methotrexate

  • 18. 
    If the patient is taking phenytoin for seizures, which of the following drugs should be avoided?
    • A. 

      Lansoprazole

    • B. 

      Omeprazole

    • C. 

      Rabeprazole

    • D. 

      Pantoprazole

  • 19. 
    Which of the following, concerning PPIs, is false?
    • A. 

      PPIS should be taken 30-60 minutes before a meal.

    • B. 

      PPIs should be chewed or crushed to promote absorption

    • C. 

      PPIs are used to treat erosive esophagitis

    • D. 

      Duration of therapy for a gastric ulcer is 4-8 weeks

  • 20. 
    Which of the following causes gynecomastia?
    • A. 

      Nizatidine

    • B. 

      Bismuth

    • C. 

      Esomeprazole

    • D. 

      Cimetidine

  • 21. 
    How does sucralfate promote mucosal defenses in PUD?
    • A. 

      It binds with food in the stomach to form a paste-like substance that promotes healing

    • B. 

      It reduces stomach acid

    • C. 

      It reacts with hydrochloric acid in the stomach and binds to the surface of the ulcer

    • D. 

      It inhibits the secretion of H+ ions from parietal cells in the stomach

  • 22. 
    Which of the following is the shortest treatment for h. pylori?
    • A. 

      Lansoprazole, clarithromycin, amoxicillin (Tritec)

    • B. 

      Bismuth, metronidazole, tetracycline (Helidac)

    • C. 

      Esomeprazole, clarithromycin, amoxicillin

    • D. 

      Rabeprazole, clarithromycin, amoxicillin

  • 23. 
    Which is true of metoclopramide in the treatment of GERD?
    • A. 

      It is not used

    • B. 

      It increases LES tone

    • C. 

      It decreases peristalsis

    • D. 

      It is the only medicine safe to use in patients on MAOIs

  • 24. 
    Which of the following is not a 5-aminosalicylate?
    • A. 

      Lamivudine

    • B. 

      Sulfasalazine

    • C. 

      Mesalamine

    • D. 

      Olsalazine

  • 25. 
    Which of the following is released in the terminal ileum for disease affecting the ileum or ascending colon, but has low systemic bioavailability?
    • A. 

      Prednisone

    • B. 

      Hydrocortisone

    • C. 

      Azathioprine

    • D. 

      Budesonide

Back to Top Back to top