Pharm Practice Quiz 4

53 Questions | By Day4517 | Last updated: Mar 22, 2022 | Total Attempts: 3396

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N/V/D, constipation, PUD, GERD, IBD, hepatitis, cirrhosis

Questions and Answers

1.

Which of the following receptors is not involved in nausea and vomiting?
- A.
  
  Dopamine
- B.
  
  Acetylcholine
- C.
  
  Histamine
- D.
  
  Serotonin
- E.
  
  All of these are involved
2.

Which of the following first-line antiemetics does not cause extrapyramidal symptoms?
- A.
  
  Phenothiazines
- B.
  
  Serotonin (5-HT3) antagonists
- C.
  
  Butyrophenones
- D.
  
  Benzamides
- E.
  
  None of the above
3.

What is the MOA of benzamides?
- A.
  
  Inhibition of serotonin receptors in the vomiting center
- B.
  
  Direct dopamine antagonism at the chemoreceptor trigger zone
- C.
  
  Inhibition of dopamine receptors in the gastrointestinal tract and chemoreceptor trigger zone
- D.
  
  Inhibition of cholinergic receptors, which decreases stimulation of the vomiting center
4.

Which of the following is used for anticipatory nausea?
- A.
  
  Cannabinoids
- B.
  
  Benzodiazepines
- C.
  
  Corticosteroids
- D.
  
  Anticholinergics
- E.
  
  Benzamides
5.

Which of the following affects GABA receptors?
- A.
  
  Cannabinoids
- B.
  
  Anticholinergics
- C.
  
  Phenothiazines
- D.
  
  Benzodiazepines
6.

Which of these antiemetic drugs do not cause blurred vision?
- A.
  
  Butyrophenones
- B.
  
  Phenothiazines
- C.
  
  Cannabinoids
- D.
  
  Antihistamines
7.

Which of the following iss indicated for severe nausea and vomiting?
- A.
  
  Benzodiazepines
- B.
  
  Dexamethasone
- C.
  
  Phenothiazines
- D.
  
  Serotonin antagonists
8.

Which antidiarrheal agent agent is only available by prescription?
- A.
  
  Loperamide
- B.
  
  Diphenoxylate/atropine sulfate
- C.
  
  Bismuth subsalicylate
- D.
  
  Attapulgite
9.

Which drug should be used cautiously in infectious diarrhea?
- A.
  
  Polycarbophil
- B.
  
  Bismuth subsalicyclate
- C.
  
  Loperamide
- D.
  
  Fiber supplements
10.

What is the main use for bismuth subsalicylate?
- A.
  
  Chronic diarrhea
- B.
  
  Constipation
- C.
  
  Traveler's diarrhea
- D.
  
  Anticipatory nausea
11.

Which of the following is not a bulk-forming laxative?
- A.
  
  Psyllium
- B.
  
  Polycarbophil
- C.
  
  Lactulose
- D.
  
  Methylcellulose
12.

Which is a contraindication of lubricant laxative use?
- A.
  
  Renal dysfunction
- B.
  
  Recumbent patients
- C.
  
  Use simultaneously with psyllium
- D.
  
  Flatulence
13.

Which drug is metabolized to solutes in the GI tract, which moves water osmotically and facilitates propulsion and evacuation?
- A.
  
  Milk of magnesia
- B.
  
  Prune juice
- C.
  
  ExLax
- D.
  
  Sorbitol
14.

Which would not cause problems?
- A.
  
  Colace and mineral oil
- B.
  
  Mineral oil and vitamin K
- C.
  
  Milk of magnesia in a patient with renal dysfunction
- D.
  
  Methylcellulose and mineral oil
15.

Which is first line treatment for chronic mild to moderate GERD?
- A.
  
  Antacids
- B.
  
  H2 antagonists
- C.
  
  PPIs
- D.
  
  Sucralfate
16.

Which of the following properties of NSAIDs contributes to formation of ulcers?
- A.
  
  Decrease in thromboxane
- B.
  
  Inhibition of cox-1
- C.
  
  Inhibition of cox-2
- D.
  
  Decrease in arachidonic acid
17.

Which drug can prevent formation of NSAID induced ulcers?
- A.
  
  Metronidazole
- B.
  
  Mesalamine
- C.
  
  Misoprostol
- D.
  
  Methotrexate
18.

If the patient is taking phenytoin for seizures, which of the following drugs should be avoided?
- A.
  
  Lansoprazole
- B.
  
  Omeprazole
- C.
  
  Rabeprazole
- D.
  
  Pantoprazole
19.

Which of the following, concerning PPIs, is false?
- A.
  
  PPIS should be taken 30-60 minutes before a meal.
- B.
  
  PPIs should be chewed or crushed to promote absorption
- C.
  
  PPIs are used to treat erosive esophagitis
- D.
  
  Duration of therapy for a gastric ulcer is 4-8 weeks
20.

Which of the following causes gynecomastia?
- A.
  
  Nizatidine
- B.
  
  Bismuth
- C.
  
  Esomeprazole
- D.
  
  Cimetidine
21.

How does sucralfate promote mucosal defenses in PUD?
- A.
  
  It binds with food in the stomach to form a paste-like substance that promotes healing
- B.
  
  It reduces stomach acid
- C.
  
  It reacts with hydrochloric acid in the stomach and binds to the surface of the ulcer
- D.
  
  It inhibits the secretion of H+ ions from parietal cells in the stomach
22.

Which of the following is the shortest treatment for h. pylori?
- A.
  
  Lansoprazole, clarithromycin, amoxicillin (Tritec)
- B.
  
  Bismuth, metronidazole, tetracycline (Helidac)
- C.
  
  Esomeprazole, clarithromycin, amoxicillin
- D.
  
  Rabeprazole, clarithromycin, amoxicillin
23.

Which is true of metoclopramide in the treatment of GERD?
- A.
  
  It is not used
- B.
  
  It increases LES tone
- C.
  
  It decreases peristalsis
- D.
  
  It is the only medicine safe to use in patients on MAOIs
24.

Which of the following is not a 5-aminosalicylate?
- A.
  
  Lamivudine
- B.
  
  Sulfasalazine
- C.
  
  Mesalamine
- D.
  
  Olsalazine
25.

Which of the following is released in the terminal ileum for disease affecting the ileum or ascending colon, but has low systemic bioavailability?
- A.
  
  Prednisone
- B.
  
  Hydrocortisone
- C.
  
  Azathioprine
- D.
  
  Budesonide