Patho Ch 19 Quiz

22 Questions | Total Attempts: 414

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Pathology Quizzes & Trivia

Questions and Answers
  • 1. 
    Partial or complete failure of development of the thymus and parathyroid glands
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 2. 
    Acquired later in life
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 3. 
    Low IgG and IgA levels, high IgM concentrations 
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 4. 
    Essentially undetectable levels of all serum immunoglobulins
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 5. 
    In levels of serum and secretory IgA
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 6. 
    Cause of severe combined immunodeficiency disease
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 7. 
    Repeated bouts of upper respiratory and middle ear infections
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 8. 
    Lymphopenia and a decrease in the ratio of CD4+ helper T cells to CD8+ suppressor T cells
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 9. 
    Terminal differentiation of mature B cells to plasma cells is blocked
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 10. 
    Decreases in one or more IgG subgroups
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 11. 
    Susceptible to infections caused by encapsulated microorganisms
    • A. 

      DiGeorge Syndrome

    • B. 

      Secondary Immunodeficiency

    • C. 

      Hyper-IgM syndrome

    • D. 

      X-linked agammaglobulinemia

    • E. 

      Selective IgA deficiency

    • F. 

      Adenosine deaminase deficiencies and T-cell cytokine receptor mutations

    • G. 

      Transient hypogammaglobulinemia of infancy

    • H. 

      Ataxia-telangiectasia

    • I. 

      Common variable immunodeficiency

    • J. 

      Immunoglobulin G subclass deficiency

    • K. 

      Wiskott-Aldrich syndrome

  • 12. 
    IgE-mediated disorders
    • A. 

      Type I hypersensitivity reaction

    • B. 

      Type II hypersensitivity reaction

    • C. 

      Type III hypersensitivity reaction

    • D. 

      Type IV hypersensitivity reaction

  • 13. 
    Antibody-mediated disorders
    • A. 

      Type I hypersensitivity reaction

    • B. 

      Type II hypersensitivity reaction

    • C. 

      Type III hypersensitivity reaction

    • D. 

      Type IV hypersensitivity reaction

  • 14. 
    Complement-mediated immune disorders
    • A. 

      Type I hypersensitivity reaction

    • B. 

      Type II hypersensitivity reaction

    • C. 

      Type III hypersensitivity reaction

    • D. 

      Type IV hypersensitivity reaction

  • 15. 
    T-cell mediated disorders
    • A. 

      Type I hypersensitivity reaction

    • B. 

      Type II hypersensitivity reaction

    • C. 

      Type III hypersensitivity reaction

    • D. 

      Type IV hypersensitivity reaction

  • 16. 
    Infants are born with a passive immunity that occurs when immunoglobulin antibodies cross the placenta from the maternal circulation prior to birth. Which immunoglobulin is capable of crossing the placenta?
    • A. 

      IgM

    • B. 

      IgD

    • C. 

      IgG

    • D. 

      IgE

  • 17. 
    Primary cell-mediated disorders of the immune system cause severe problems with infections. Children with these disorders rarely survive beyond childhood without a bone marrow transplant. Which of the following is a disease that involves primary cell-mediated disorders of the immune system?
    • A. 

      DiGeorge syndrome

    • B. 

      Y-Linked hyper-IgM syndrome

    • C. 

      X-Linked agammaglobulinemia

    • D. 

      Y-linked agammaglobulinemia

  • 18. 
    Combined immunodeficiency syndrome is a disorder in which both B and T lymphocytes are affected. This results in defects in both humoral and cell-mediated immunity. What could be the cause of this disorder?
    • A. 

      Multiple misplaced genes that influence lymphocyte development and response

    • B. 

      A single mutation in any gene that influences major histocompatibility antigens

    • C. 

      A single misplaced gene that influences major histocompatibility

    • D. 

      Multiple mutations in genes that influence lymphocyte development and response

  • 19. 
    Drug-induced secondary hypogammaglobulinemia are reversible. Which of the following is not a drug that produces hypogammaglobulinemia?
    • A. 

      Phenytoin

    • B. 

      Corticosteroids

    • C. 

      Carbamazepine

    • D. 

      Disease modifying antirheumatic drugs

    • E. 

      Interferon-beta 1a drugs

  • 20. 
    Combined immunodeficiency syndrome (CIDS) is distinguished by low, not absent, T-cell function. These diseases are usually associated with other disorders and arise from diverse genetic causes. Which of the following diseases is considered a CIDS?
    • A. 

      Pierre-Robin syndrome

    • B. 

      Angelman syndrome

    • C. 

      Ataxia-telangiectasia

    • D. 

      Adair-Dighton syndrome

  • 21. 
    The immune system typically responds to invaders of all types in our bodies. However, it can also cause tissue injury and disease. What is this effect called?
    • A. 

      Hypersensitivity reaction

    • B. 

      Antigen reaction

    • C. 

      Mediator response action

    • D. 

      Allergen stimulating reaction

  • 22. 
    Some people are so sensitive to certain antigens that they react within minutes by developing itching, hives, and skin erythema, followed shortly thereafter by bronchospasm and respiratory distress. What is this commonly known as?
    • A. 

      Antigen reaction

    • B. 

      Anaphylactic reaction

    • C. 

      Hyposensitive reaction

    • D. 

      Arthus reaction