Literally, a pharmparty is a situation in which we have random exchange in prescription drugs to be toxicated. This quiz however, dwells more on the different aspects of drugs and chemical components.
Patient's gender
Patient's age
Patient's disease state
Patient's body composition
All of the above
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Zero order
First order
Neither
Both
All of the above
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Phase 1
Phase 2
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Weak acid
Weak base
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Increase enzyme degradation rate
Increase enzyme synthesis rate
Both
Neither
All of the above
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1%
10%
50%
90%
99%
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Don't pick me, I am wrong (FREEEBIE!!!)
Relatively nonpolar
Generally biologically active
Rapidly excreted in the urine
All of the above
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Liver
Lung
Kidney
None of the above
All of the above
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Weak acids are usually excreted slower in alkaline urine
Weak bases are usually excreted faster in acidic urine
Both
Neither
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Weak acid (pKa 7.4)
weak base (pKa 8.4)
Weak acid (pKa 8.4)
Weak base (pKa 6.4)
Weak acid (pKa 6.4)
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Relatively lipid-soluble
Probably uncharged
Both
Neither
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Extreme drug instability at stomach pH
Hepatic "first-pass" effect
drug metabolized by gut flora
tablet does not dissolve
Patient non-complance
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More of the weak acid drug will be in the lipid-soluble form at alkaline pH.
More of the weak acid drug will be in the lipid soluble form at acid pH.
More of the weak base drug will be in the lipid soluble form at alkaline pH
A & C
B & C
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