Molecular Basis Of Inheritance

15 Questions | By Jagranjosh | Updated: Mar 22, 2022 | Attempts: 1784

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Time: 30 Minute

Questions and Answers

1.

Select the incorrect option for genetic code?
- A.
  
  It is nearly universal
- B.
  
  It is degenerate
- C.
  
  It is unambiguous
- D.
  
  A codon in mRNA is read in a non contiguous fashion
2.

Removal of introns and joining the exons in a defined order in a transcription unit is called
- A.
  
  Tailing
- B.
  
  Transformation
- C.
  
  Capping
- D.
  
  Splicing
3.

Discontinuous synthesis of DNA occurs in one strand, because:
- A.
  
  DNA molecule being synthesized is very long
- B.
  
  DNA dependent DNA polymerase catalyses polymerization only in one direction (5' - 3')
- C.
  
  It is a more efficient process
- D.
  
  DNA ligase has to have a role
4.

Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
- A.
  
  Rosalind Francklin
- B.
  
  Maurice Wilkins
- C.
  
  Erwin Chargaff
- D.
  
  Meselson and Stahl
5.

Which of the following steps in transcription is catalysed by RNA polymerase?
- A.
  
  Initiation
- B.
  
  Elongation
- C.
  
  Termination
- D.
  
  All of the above
6.

Which of the following are the functions of RNA?
- A.
  
  It is a carrier of genetic information from DNA to ribosomes synthesizing polypetides
- B.
  
  It carries amino acids to ribosomes
- C.
  
  It is a constituent component of ribosomes
- D.
  
  All of the above
7.

In some viruses, DNA is synthesized by using RNA as template. Such a DNA is called:
- A.
  
  A-DNA
- B.
  
  B-DNA
- C.
  
  CDNA
- D.
  
  RDNA
8.

If Meselson and Stahl's experiment is continued for four generations is bacteria, the ratio of 15N/ 15N: 15N/14N: 14 N/14N containing DNA in the fourth generation would be:
- A.
  
  1:1:0
- B.
  
  1:4:0
- C.
  
  0:1:3
- D.
  
  0:1:7
9.

If the base sequence of a codon in mRNA is 5' AUG-3', the sequence of tRNA pairing with it must be:
- A.
  
  5' UAC – 3'
- B.
  
  5' - CAU - 3'
- C.
  
  5' -AUG - 3'
- D.
  
  5' - GUA - 3'
10.

If the sequence of nitrogen base of the coding strand of DNA in a transcription unit is:
- A.
  
  5' – A U G AA U G - 3'
- B.
  
  5' – U A C U U A C - 3'
- C.
  
  5' – C AU U C A U - 3'
- D.
  
  5' – G U A A G U A - 3'
11.

The initiate translation, the mRNA first blinds to:
- A.
  
  The smaller ribosomal sub-unit
- B.
  
  The larger ribosomal sub-unit
- C.
  
  The whole ribosome
- D.
  
  No such specificity exists
12.

In E.Coil, the lac Operon gets switched on when:
- A.
  
  Lactose is present and it binds to the repressor
- B.
  
  Repressor binds to operator
- C.
  
  RNA polymerase binds to the operator
- D.
  
  Lactose is present and it binds to RNA polymerase
13.

Which of the following sequence will be produced as a result of transcription of the DNA sequence –CGATTACAG
- A.
  
  GCUAAUGUC
- B.
  
  CGUAAUCUG
- C.
  
  GCTAATGTC
- D.
  
  GCUAATCTG
14.

Sickle-cell haemoglobin has valine in place of glutamic acid at position 6 in the f3 polypeptide chain. Reason: Sickle-cell anaemia is expressed only in homozygous recessive state.
- A.
  
  If both A and R are true R is the correct explanation of A
- B.
  
  If both A and R are true but R is not the correct explanation of A
- C.
  
  If A is true but R is false
- D.
  
  If both A and R are false
15.

DNA fingerprinting is very well known for its application in paternity testing is case of disputes. Reason: It employs the principle of polymorphism in DNA sequences as the polymorphisms are inheritable from parents to children
- A.
  
  If both A and R are true R is the correct explanation of A
- B.
  
  If both A and R are true but R is not the correct explanation of A
- C.
  
  If A is true but R is false
- D.
  
  If both A and R are false