Protein Metabolism I

15 Questions | Total Attempts: 365

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Protein Metabolism I

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Questions and Answers
  • 1. 
    Which of these RNA species is the most abundant in translation?
    • A. 

      TRNA

    • B. 

      MRNA

    • C. 

      RRNA

  • 2. 
    Which of these are stop codons?
    • A. 

      UAA

    • B. 

      UGA

    • C. 

      AUC

    • D. 

      UAG

    • E. 

      UGG

  • 3. 
    Which of these anticodon bases can bind with the 3' codon base A U and C?
    • A. 

      A

    • B. 

      U

    • C. 

      I

    • D. 

      G

    • E. 

      C

  • 4. 
    AUG is designated for which amino acid (which also starts all protein synthesis)?
    • A. 

      Cys

    • B. 

      Asn

    • C. 

      Phe

    • D. 

      Met

  • 5. 
    How is the anticodon for 5' CGC 3' read?
    • A. 

      GCI

    • B. 

      ICG

  • 6. 
    Which mutation changes the codon to a stop codon?
    • A. 

      Silent

    • B. 

      Nonsense

    • C. 

      Missense

    • D. 

      Radioactive spider bite

  • 7. 
    Which mutation changes the codon to code for another amino acid?
    • A. 

      Silent

    • B. 

      Nonsense

    • C. 

      Missense

    • D. 

      Radioactive spider bite

  • 8. 
    Which of the following in prokaryotes are orthologs in eukaryotes?
    • A. 

      5S rRNA; 5S rRNA

    • B. 

      5S rRNA; 5.8S rRNA

    • C. 

      23S rRNA; 28S rRNA

    • D. 

      16S rRNA; 18S rRNA

    • E. 

      18S rRNA; 28S rRNA

  • 9. 
    Aminoacylation of tRNA by aminoacyl-tRNA synthetases works in two steps: 1.  Amino acid activation by ________ with the release of phosphate ions. 2.  Binding of the activated amino acid to terminal A residue of the tRNA with release of ________.
    • A. 

      GTP; AMP

    • B. 

      AMP; ATP

    • C. 

      ATP; AMP

  • 10. 
    During the removal of coupling errors, the correct amino acid will not be able to fit into the editing site
    • A. 

      True

    • B. 

      False

  • 11. 
    The role is formylation is that methionyl-tRNA fmet cannot be inserted into the ____________ of a growing peptide.
  • 12. 
    Before translation starts in prokaryotes two things need to happen pairing of mRNA with the 3' end of the ______ rRNA mediated by the __________ sequence, and pairing of mRNA initiation codon with ___________ of initiator tRNA molecule.
    • A. 

      16S Shine Delgarno, codon

    • B. 

      16S, Shine Delgarno; anticodon

    • C. 

      5S; Shine Delgarno; anticodon

    • D. 

      18S; Shine delgarno; anticodon

  • 13. 
    _________ prevents the 30S and 50S subunit from combining prematurely in bacterial translation, and _____ prevents the use of the A site in the initiation.
    • A. 

      IF3; IF2

    • B. 

      IF3; IF1

    • C. 

      IF1; IF3

    • D. 

      IF2; IF1

  • 14. 
    Which of the following bindings are incorrectly paired up for eukaryotic initiation complex formation?
    • A. 

      MRNA > 3' end by PAB

    • B. 

      EIF4E > 5' cap of mRNA

    • C. 

      EIF4G > eIF4E and PAB

    • D. 

      EIF4E > 3' end by PAB

  • 15. 
    In order for the eIF protein to scan the 40S ribosomal subunit for  the first AUG it needs helicase activity to resolve the secondary structure in the 5'UTR of the mRNA and does not require ATP for this to take place.
    • A. 

      True

    • B. 

      False