Molecular Biology (Chapter 1-5, 20-23)
These are the powerpoint questions he asked I'll add some randoms one later when I get through reading all the chapters. Good luck.
- 1.Some genes located on the same chromosome do not show perfect linkage because?
- A.
They are too close together
- B.
The are interrupted by other genes
- C.
Crossover events occur between homologous genes
- D.
Some genes are deleted
- E.
Too many alleles are present
- 2.
- A.
The gene for eye color is located on the X chromosome
- B.
The eye color phenotype is sex-linked
- C.
The females are homozygotes
- D.
The gene for eye color is located on an autosome
- E.
Both (A) and (B) are correct
- 3.Which of the following statements is not true regarding genetic mapping?
- A.
Genes are arragned in a linear order on chromosomes
- B.
Recombination occurs between chromosomes
- C.
There is a mathematical relationship between the distance separtating two genes and the recombination frequency
- D.
Mapping is used to establish the location of genes relative to each other
- E.
Mapping is used to determine the composition of a gene.
- 4.Evidence that physical recombination occurs between two chromosomes was provided by?
- A.
McClintock and Creighton
- B.
Watson and Crick
- C.
Avery, McLeod and McCarthy
- D.
Hershey and Chase
- E.
Miescher and Morgan
- 5.The chromosomal theory of inheritance holds that
- A.
Chromosomes vary in size
- B.
The number of chromosomes vary in individuals
- C.
Chromosomes contain histone protiens
- D.
Genes are arranged in a linear order on chromosomes
- E.
Chromosomes condense during mitosis
- 6.Which of the following was demonstrated by Frederick and Griffiths?
- A.
Nuclein was the possible genetic material
- B.
A genetic trait can be transferred from one organism to another
- C.
Genes are linked
- D.
Corssing over occurs between chromosomes
- E.
Protein is a major component of nuclein.
- 7.Who first conducted the X-ray diffraction studies of DNA?
- A.
Franklin and Wilkins
- B.
Miescher and McClintock
- C.
Wason and Crick
- D.
Meselson and Stahl
- E.
Avery and Beadle
- 8.Which of the follwing scientists provided definitive evidence for the chromosomal theory?
- A.
Mendel
- B.
Morgan
- C.
McClintock
- D.
Miescher
- E.
Avery
- 9.The relationship between genes and enzymes was shown by?
- A.
Watson and Crick
- B.
Beadle and Tatum
- C.
Avery and McLeod
- D.
Morgan and Mendel
- E.
Miescher and Stern
- 10.The notion of one-gene/one-enzyme is true or not? If not, it is because of which of the following?
- A.
An enzyme can be composed of more than one polypeptide
- B.
Many genes contain the information for making polypeptides that are not enzymes.
- C.
The end products of some genes are not polypeptides
- D.
All A-C are correct
- E.
Only A and B are correct
- 11.Which of the following is not a product of transcription?
- A.
RNA
- B.
DNA
- C.
RRNA
- D.
TRNA
- E.
MRNA
- 12.Which of the following is true about wild-type organisms?
- A.
They are always foudn in the wild.
- B.
They are free of all mutations.
- C.
They are also referred to as standard-types
- D.
They carry no recessive genes.
- E.
None of the choices
- 13.The correct structure of DNA components can be presented as
- A.
Phosphate–base–sugar
- B.
Phosphate-sugar-base
- C.
Base-phosphate-sugar
- D.
Phosphate-sugar-phosphate-base
- E.
Base-sugar-phosphate-base
- 14.Which of the following is a characteristic of double-stranded DNA?
- A.
2 nanometers in width
- B.
10 base pairs per turn
- C.
0.34 nanometers per basepair
- D.
A and B
- E.
A, B and C
- 15.Which of the following DNA molecules is the most stable?
- A.
CTGCATAC GACGTATG
- B.
GAAATTTC CTTTAAAG
- C.
AGTCGAAT TCAGCTTA
- D.
GCGTGCAC CGCACGTG
- E.
GGATCCTG CCTAGGAC
- 16.Double-stranded DNA consists of two antiparallel strands, meaning that one strand is oriented in the 5' to 3' direction, while the other is oriented in the 3' to 5' direction.
- A.
True
- B.
False
- 17.Asymmetrical spacing of the backbones of the DNA double helix generates major and minor grooves.
- A.
True
- B.
False
- 18.In experiments conducted by Griffitsh, the inabilityy of the avirulent strain to produce a lethal infection was due to
- A.
The presence of a protective
- B.
Destruction by the host's white blood cells
- C.
The presence of a gene for a polysaccharide coat
- D.
The high body temperature of the host
- E.
None of the choices are correct
- 19.Experiments conducted by Frederick Griffiths laid the foundation for?
- A.
Elucidation of mRNA structure
- B.
DNA as the genetic material
- C.
The virulence of S. pneumoniae
- D.
The discovery of the capsule of S. pneumoniae
- E.
Elucidaiton of tRNA structure.
- 20.Which of the following would be the substance of choice to destroy the DNA in a solution?
- A.
Ribonuclease
- B.
Trypson
- C.
Chymotrypsin
- D.
Deoxyribonuclease
- E.
None of the choices are correct
- 21.The analytic tools used to show that DNA was the transforming substance include all of the following except
- A.
Ultracentrifugation
- B.
Electrophoresis
- C.
UV absorption spectrophotometry
- D.
Heat inactivation
- E.
Chemical analysis
- 22.All of the following are found in RNA except
- A.
Adenine
- B.
Deoxyribose
- C.
Cytosine
- D.
Guanine
- E.
Uracil
- 23.Which of the following is not found in RNA and DNA?
- A.
Nitrogen
- B.
Oxygen
- C.
Carbon
- D.
Sulfur
- E.
Hydrogen
- 24.The bonds that connect adenine to thymine in a DNA double helix are
- A.
Ionic
- B.
Hydrophobic
- C.
Hydrogen
- D.
Covalent
- E.
One of the choices are correct
- 25.Phosphodiester bonds are examples of
- A.
Hydrophobic interactions
- B.
Hydrogen bonds
- C.
Convalent bonds
- D.
Noncovalent bonds
- E.
Ionic bonds
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