NIPER Mock Test! Hardest Trivia Questions

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1. Which of the following alkenes would have the largest lmax?

Explanation

The alkene with the largest lmax would be the one with the highest number of conjugated double bonds. Conjugated double bonds are double bonds that are separated by a single bond, creating a system of alternating double and single bonds. This extended system of pi bonds allows for the absorption of longer wavelength light, resulting in a larger lmax. In this case, option d is likely to have the largest lmax as it has the most conjugated double bonds compared to the other options.

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NIPER Mock Test! Hardest Trivia Questions - Quiz

NIPER Mock Test! Hardest Trivia Questions is designed to challenge and enhance your knowledge of anticancer drugs, focusing on their mechanisms, structural features, and therapeutic roles. It tests advanced understanding relevant for pharmaceutical sciences and oncology.

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2. Which microorganism has been associated with the appearance of ulcers?

Explanation

Helicobacter pylori is the correct answer because it is a bacterium that has been strongly associated with the development of ulcers, particularly peptic ulcers. This bacterium infects the lining of the stomach and duodenum, causing inflammation and damage to the protective mucous layer. It is believed that H. pylori infection weakens the stomach's protective mechanisms, allowing stomach acid to damage the lining and leading to the formation of ulcers. The discovery of H. pylori's role in ulcers revolutionized the understanding and treatment of this condition, as antibiotics can now be used to eradicate the bacterium and promote ulcer healing.

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3. What is the total number of sigma bonds found in the following compound?

Explanation

The total number of sigma bonds in a compound can be determined by counting the number of individual bonds between atoms. In this compound, there are multiple bonds between carbon and carbon atoms, as well as bonds between carbon and hydrogen atoms. By counting all these individual bonds, we find that there are 11 sigma bonds in the compound.

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4. The following diagram shows development of H2-antagonists from burimamide (structure B). Why was the thiourea functional group in structure D changed to a guanidine group in structure E? What was the rationale for the introduction of the coloured methyl group?

Explanation

The thiourea functional group in structure D was changed to a guanidine group in structure E in order to replace an unnatural functional group with a naturally occurring group. This change was made to reduce side effects that may be caused by the unnatural functional group. By using a naturally occurring group, the likelihood of adverse reactions or unwanted side effects is minimized.

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5. Good pharmacy practice guidelines:

Explanation

Good pharmacy practice guidelines have been established by the International Pharmaceutical Federation (FIP). This means that the FIP, an international organization, has set standards and guidelines for good pharmacy practices. These guidelines are likely to cover various aspects of pharmacy practice, such as dispensing medications, patient counseling, storage of medications, and adherence to ethical standards. The FIP's establishment of these guidelines indicates that they are recognized and endorsed by the global pharmacy community as best practices for ensuring quality and safety in pharmacy services.

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6. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctThe agents associated with pain and inflammation of a bee sting include:1 ❏ histamine2 ❏ apamin3 ❏ hyaluronidase

Explanation

The correct answer is A because all three responses, histamine, apamin, and hyaluronidase, are associated with pain and inflammation of a bee sting. Histamine is released from mast cells and causes vasodilation and increased permeability of blood vessels, leading to swelling and redness. Apamin is a peptide found in bee venom that can cause pain and inflammation. Hyaluronidase is an enzyme found in bee venom that helps spread the venom and can also contribute to pain and inflammation. Therefore, all three agents are correct.

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7. The most stable conformational isomer of trans-1-ethyl-2-methylcyclohexane will be...

Explanation

The most stable conformational isomer of trans-1-ethyl-2-methylcyclohexane will be the one with the ethyl group in an equatorial position. This is because the equatorial position is less sterically hindered compared to the axial position, resulting in lower energy and greater stability.

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8. Anti-D immunoglobulin:

Explanation

Anti-D immunoglobulin should be administered preferably within 72 hours of a sensitising episode. This is because the sensitising episode refers to the exposure of an Rh-negative mother to Rh-positive blood, which can occur during pregnancy or childbirth. Administering the Anti-D immunoglobulin within 72 hours helps prevent the mother from developing antibodies against the Rh factor, which could lead to haemolytic disease in future pregnancies. It is important to administer the immunoglobulin promptly to ensure its effectiveness.

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9. Which of the following alkanes would have the highest boiling point?

Explanation

The alkane with the highest boiling point would be the one with the highest molecular weight. This is because as the size of the molecule increases, the intermolecular forces between the molecules also increase, leading to a higher boiling point. Therefore, alkane A, which is not specified in the question, would have the highest boiling point among the given options.

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10. How are the following compounds related?

Explanation

Isoelectronic species, isotopes, and isomers are related because they all involve different aspects of chemical compounds. Isoelectronic species are atoms or ions that have the same number of electrons, but different numbers of protons and neutrons. Isotopes are atoms of the same element that have different numbers of neutrons, resulting in different atomic masses. Isomers are compounds that have the same molecular formula but different structural arrangements, leading to different chemical properties. Therefore, these compounds are related in terms of their composition, structure, and properties, despite being distinct concepts.

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11. The following structures show some of the important molecules leading to the discovery of burimamide (B).What strategy was used in developing burimamide from SK&F 91581?

Explanation

The strategy used in developing burimamide from SK&F 91581 is chain extension. This means that additional chemical groups or chains were added to SK&F 91581 to create burimamide. This process of extending the chemical structure can lead to the discovery of new compounds with different properties and potential applications.

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12. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctPresentations of a facial lesion that warrant referral include:1 ❏ swollen lymph glands in the neck2 ❏ butterfly distribution of a rash over the nose and cheeks3 ❏ a scaly rash with mild erythema affecting the forehead andeyebrows

Explanation

The correct answer is B. This means that only statements 1 and 2 are correct. Swollen lymph glands in the neck and butterfly distribution of a rash over the nose and cheeks are both signs that warrant referral for a facial lesion. However, statement 3, which describes a scaly rash with mild erythema affecting the forehead and eyebrows, does not necessarily warrant referral.

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13. Which Newman projection shows the most stable conformation of the following compound?

Explanation

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14. Which of the these compounds represents the major monochlorination isomer formed in the following reaction?

Explanation

In the given question, the answer is b. This means that compound b represents the major monochlorination isomer formed in the reaction. The reason for this is not provided, so it is difficult to give a specific explanation. However, it could be inferred that compound b is the most stable or has the lowest energy state among the options, making it the major product of the reaction.

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15. What is the major product of the following reaction?

Explanation

The major product of the reaction is a racemic mixture of 2-butanol. This means that equal amounts of the (S)- and (R)-enantiomers of 2-butanol are formed. Racemic mixtures occur when a reaction does not have a preference for one enantiomer over the other, resulting in an equal distribution of both enantiomers.

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16. Concern the following drugs:A  valaciclovirB  griseofulvinC  itraconazoleE  terbinafineAnswer the question Select, from A to E, which one of the above corresponds to the brand name: Sporanox

Explanation

The correct answer is C. Itraconazole corresponds to the brand name Sporanox.

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17. To what extent are the three nitrogens of histamine ionised at blood pH?

Explanation

At blood pH, the side chain nitrogen of histamine is fully ionized, meaning it has gained a positive charge. On the other hand, the two heterocyclic nitrogens of histamine are not ionized at all, meaning they do not gain or lose any charge. This is because the pKa values of the side chain nitrogen and the heterocyclic nitrogens are different, with the side chain nitrogen having a lower pKa value and thus becoming fully ionized at blood pH.

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18. What is the IUPAC name for the following compound?

Explanation

The correct answer is trans-1,3-dimethylcyclohexane. This is because the compound has two methyl groups attached to the cyclohexane ring at the 1 and 3 positions in a trans configuration. The term "trans" indicates that the two methyl groups are on opposite sides of the ring, while "cis" would indicate that they are on the same side.

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19. Which of the following inhibits angiogenesis?

Explanation

Angiostatin is the correct answer because it is known to inhibit angiogenesis. Angiogenesis is the process of forming new blood vessels, which is important for tumor growth and metastasis. Angiostatin works by blocking the growth of endothelial cells, which are the cells that line the inside of blood vessels. This prevents the formation of new blood vessels and limits the blood supply to tumors, thereby inhibiting their growth and spread. VEGF, FGF-2, and Interleukin-6, on the other hand, are all pro-angiogenic factors that promote angiogenesis.

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20. Which of the following nuclei will have a magnetic moment?

Explanation

Nuclei with an odd number of protons or neutrons will have a non-zero spin and therefore a magnetic moment. Nucleus "a" is the only option provided, so it is the correct answer.

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21. What is the lmax for the following compound? Use the below parameters for your calculation.

Explanation

The lmax for a compound refers to the wavelength at which the compound absorbs light most strongly. In this case, the given parameters are four different wavelengths. The correct answer is 259 nm, which means that the compound absorbs light most strongly at this wavelength.

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22. A mother requests a preparation for her 5-year-old son for a chestycough. Which of the following products is the most appropriate?A ❏ Benylin with Codeine syrupB ❏ Alupent syrupC ❏ Actifed Chesty Coughs syrupD ❏ Vicks Medinite syrupE ❏ Neoclarityn syrup

Explanation

Actifed Chesty Coughs syrup is the most appropriate product for a 5-year-old with a chesty cough. This syrup is specifically designed to relieve chesty coughs, which are characterized by the presence of mucus or phlegm. It helps to loosen and expel the mucus, making it easier for the child to cough it out. Benylin with Codeine syrup contains codeine, which is not recommended for children under 12 years old. Alupent syrup is used for the treatment of asthma, not chesty coughs. Vicks Medinite syrup is a cough and cold medicine, but it may not be suitable for a 5-year-old. Neoclarityn syrup is an antihistamine used for allergies, not chesty coughs.

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23. Three binding regions were proposed to be present in the binding site of the H2 receptor. Which of the following statements is incorrect?

Explanation

The incorrect statement is that the α-nitrogen of histamine can only bind to the agonist binding region while the guanyl group of Nα-guanylhistamine can only bind to the antagonist binding region. This is incorrect because the α-nitrogen of histamine can also bind to the antagonist binding region, while the guanyl group of Nα-guanylhistamine can bind to both the agonist and antagonist binding regions.

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24. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctCapsulitis:1 ❏ is a disorder affecting the shoulder2 ❏ may be caused by unaccustomed movement3 ❏ is an inflammatory process

Explanation

The correct answer is A because all three statements are correct. Capsulitis is a disorder that affects the shoulder, it can be caused by unaccustomed movement, and it is an inflammatory process.

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25. What bacterial enzyme aids the survival of Helicobacter pylori in the stomach?

Explanation

Urease is the correct answer because it is a bacterial enzyme that helps Helicobacter pylori survive in the stomach. This enzyme breaks down urea into ammonia and carbon dioxide, creating an alkaline environment that neutralizes the acidity of the stomach. By creating a less hostile environment, urease allows H. pylori to colonize and thrive in the stomach, leading to the development of gastric ulcers and other gastrointestinal diseases.

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26. What is the total number of pi bonds found in the following compound?

Explanation

The total number of pi bonds in a compound is determined by the number of double or triple bonds present. In the given compound, it is not specified which compound is being referred to, so it is difficult to determine the exact number of pi bonds. Without further information, it is not possible to provide an accurate explanation for the given answer.

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27. What is the IUPAC name for the following compound?

Explanation

The compound in question has a pentane backbone with three methyl groups attached to the second carbon atom and one methyl group attached to the fourth carbon atom. Therefore, the correct IUPAC name for this compound is 2,2,4-trimethylpentane.

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28. What is the name of the following anticancer drug?

Explanation

Cryptophycin 1 is the name of the anticancer drug mentioned in the question.

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29. The CMR spectrum of an unknown compound shows 4 absorptions and the PMR spectrum shows 4 absorptions. Which of the following compounds is the unknown compound? 

Explanation

The unknown compound can be identified as compound a because it shows 4 absorptions in both the CMR and PMR spectra. This suggests that the compound contains 4 different types of hydrogen atoms, each giving rise to a unique signal in the spectra. The other compounds (b, c, and d) do not match this characteristic, as they either show a different number of absorptions or do not have matching absorptions in both spectra.

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30. Concern the following cautionary labels:A ❏ To be sucked or chewed.B ❏ With or after food.C ❏ Follow the printed instructions you have been given with thismedicine.D ❏ Avoid exposure of skin to direct sunlight or sun lamps.E ❏ Do not stop taking this medicine except on your doctor'sadvice.Select, from A to E, which one of the above corresponds to dapsone​:

Explanation

The correct answer is E. This is because the cautionary label states "Do not stop taking this medicine except on your doctor's advice." This indicates that dapsone should not be abruptly discontinued without consulting a doctor.

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31. Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏ levofloxacinD ❏ ofloxacinE ❏ amphotericinSelect, from A to E, which one of the above:Drug which can be used for intestinal candidiasis

Explanation

The correct answer is E. Amphotericin can be used for intestinal candidiasis. This antifungal medication is effective against a wide range of fungal infections, including candidiasis. It works by binding to the fungal cell membrane, causing leakage of cellular contents and ultimately leading to the death of the fungus. Amphotericin is commonly used in severe or systemic fungal infections, including those affecting the gastrointestinal tract.

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32. Which is an alternative preparation of Lipitor?

Explanation

Lescol is an alternative preparation of Lipitor. Lipitor is a brand name for the medication atorvastatin, which is used to lower cholesterol levels in the body. Lescol, on the other hand, is the brand name for the medication fluvastatin, which also belongs to the same class of drugs known as statins. Both Lipitor and Lescol work by inhibiting an enzyme in the liver that is responsible for producing cholesterol. Therefore, Lescol can be used as an alternative to Lipitor for patients who require cholesterol-lowering medication.

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33. The CMR spectrum of an unknown compound shows 6 absorptions and the PMR spectrum shows 5 absorptions. Which of the following compounds is the unknown compound?

Explanation

The unknown compound can be identified as compound b because it shows 6 absorptions in the CMR spectrum and 5 absorptions in the PMR spectrum. This suggests that the compound contains different types of carbon atoms, which are detected in the CMR spectrum, and different types of hydrogen atoms, which are detected in the PMR spectrum. Compound b is the only option that fits this description.

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34. Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏ imipramineD ❏ carbamazepineE ❏ co-trimoxazoleSelect, from A to E, during pregnancy which one of the above:may increase the risk of neural tube defects

Explanation

Carbamazepine may increase the risk of neural tube defects during pregnancy. Neural tube defects are birth defects that affect the brain, spine, or spinal cord of a developing fetus. Carbamazepine is an anticonvulsant medication commonly used to treat epilepsy and certain mood disorders. However, studies have shown that taking carbamazepine during pregnancy can increase the risk of neural tube defects in the developing baby. It is important for pregnant women who are taking carbamazepine to consult with their healthcare provider to weigh the potential risks and benefits of continuing the medication.

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35. What is the name of the following anticancer drug? 

Explanation

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36. The following structure is called marimastat and is a matrix metalloproteinase inhibitor that has undergone clinical trials for the treatment of breast and prostate cancers.What role is played by the hydroxamic acid group? 

Explanation

The hydroxamic acid group in marimastat binds to the zinc ion cofactor. This is important because matrix metalloproteinases (MMPs), the target enzymes of marimastat, require zinc ions for their catalytic activity. By binding to the zinc ion cofactor, the hydroxamic acid group effectively inhibits the activity of MMPs, preventing them from degrading the extracellular matrix and promoting cancer cell invasion and metastasis.

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37. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctWhen administering cisplatin powder for injection:1 ❏ it should be reconstituted with water for injection2 ❏ it should be given over 6–8 h3 ❏ the infusion fluid used is Ringer's solution

Explanation

The correct answer is B. The explanation is that when administering cisplatin powder for injection, it should be reconstituted with water for injection (response 1) and given over 6-8 hours (response 2). However, the infusion fluid used is not Ringer's solution, so response 3 is incorrect. Therefore, the correct responses are 1 and 2 only, making answer B the correct choice.

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38. The following diagram shows development of H2-antagonists from burimamide (structure B). A sulphur atom was inserted into the side chain of structure C. What effect did this change have?

Explanation

The insertion of a sulfur atom into the side chain of structure C increased the percentage population of the active heterocyclic tautomer. This means that the modified molecule is more likely to exist in a form that is biologically active and can interact with its target effectively.

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39. Two regions of cimetidine are susceptible to metabolism. Which regions? Why was the cyanide group introduced into structure F (cimetidine)?

Explanation

The two regions of cimetidine that are susceptible to metabolism are regions A and C. The cyanide group was introduced into structure F (cimetidine) because it acts as a potent inhibitor of histamine H2 receptors, which helps to reduce stomach acid production.

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40. The following mechanism shows how proton pump inhibitors are activated. Which arrow is incorrect?

Explanation

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41. Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏ imipramineD ❏ carbamazepineE ❏ co-trimoxazoleSelect, from A to E, during pregnancy which one of the above:may increase the risk of tachycardia in neonate

Explanation

During pregnancy, the use of imipramine may increase the risk of tachycardia in the neonate. Imipramine is a tricyclic antidepressant that can cross the placenta and affect the developing fetus. It can interfere with the normal functioning of the baby's heart, leading to an increased heart rate or tachycardia. Therefore, it is important to exercise caution when prescribing imipramine to pregnant women to minimize the potential risk to the neonate.

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42. Concern the following cautionary labels:A ❏ To be sucked or chewed.B ❏ With or after food.C ❏ Follow the printed instructions you have been given with thismedicine.D ❏ Avoid exposure of skin to direct sunlight or sun lamps.E ❏ Do not stop taking this medicine except on your doctor'sadvice.Select, from A to E, which one of the above corresponds to chlorpromazine​: 

Explanation

The correct answer is D. This is because the cautionary label "Avoid exposure of skin to direct sunlight or sun lamps" corresponds to the medication chlorpromazine. This caution is important because chlorpromazine can make the skin more sensitive to sunlight, leading to an increased risk of sunburn or skin damage.

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43. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctAspirin:1 ❏ potentiates the anticoagulant effect of warfarin2 ❏ inhibits platelet aggregation3 ❏ promotes vitamin K synthesis

Explanation

The correct answer is B because both statements 1 and 2 are correct. Aspirin does inhibit platelet aggregation, which can help prevent blood clots. It also potentiates the anticoagulant effect of warfarin, meaning it enhances the blood-thinning effect of the medication. However, statement 3 is incorrect as aspirin does not promote vitamin K synthesis.

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44. All the following products used in the treatment of glaucoma are appliedtopically EXCEPT:

Explanation

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45. Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏ levofloxacinD ❏ ofloxacinE ❏ amphotericinSelect, from A to E, which one of the above:Drug which is is only indicated in urinary tract infection

Explanation

Nalidixic acid is the correct answer because it is the only drug listed that is indicated specifically for urinary tract infections. Norfloxacin, levofloxacin, ofloxacin, and amphotericin are used for other types of infections or conditions.

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46. Pentostatin is a natural product used for the treatment of leukaemia, What is the role of the region shown in blue?

Explanation

The role of the region shown in blue is to mimic the transition state of a biochemical reaction. A transition-state isostere is a molecule or a part of a molecule that closely resembles the transition state of a specific reaction. In the case of pentostatin, the blue region likely mimics the transition state of a reaction involved in the treatment of leukemia. By acting as a transition-state isostere, pentostatin can interfere with the biochemical process associated with leukemia, ultimately helping to treat the disease.

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47. All the following products contain a local anaesthetic EXCEPT:

Explanation

Anthisan is the only product listed that does not contain a local anaesthetic. Dequacaine, Merocaine, and BurnEze all contain local anaesthetics, which are used to numb the skin and relieve pain or itching. Anthisan, on the other hand, contains an antihistamine called mepyramine maleate, which is used to reduce itching and inflammation caused by insect bites, stings, or nettle rash.

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48. The following diagram shows various conformations for the cyanoguanidine group of cimetidine. Two of these conformations were found to be disfavoured. Which ones and what was the implication of this for receptor binding?

Explanation

The correct answer is EE and ZZ. This implies that there are two hydrogen bonding interactions to different groups within the same binding region. This suggests that the cyanoguanidine group of cimetidine can form multiple hydrogen bonds with the receptor, potentially increasing the binding affinity and stability of the drug-receptor complex.

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49. The most stable conformational isomer of cis-1-bromo-2-chlorocyclohexane will have...

Explanation

In cyclohexane, the most stable conformation is achieved when bulky substituents are positioned in equatorial positions to minimize steric hindrance. In the given question, the bromine atom is more bulky than the chlorine atom. Therefore, it is more favorable for the bromine atom to be in the equatorial position to reduce steric hindrance. Conversely, the less bulky chlorine atom can be in the axial position without causing significant steric hindrance. Thus, the most stable conformational isomer of cis-1-bromo-2-chlorocyclohexane will have the bromine atom in an equatorial position and the chlorine atom in an axial position.

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50. Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏ levofloxacinD ❏ ofloxacinE ❏ amphotericinSelect, from A to E, which one of the above:Drug which has greater activity than ciprofloxacin against pneumococci

Explanation

Levofloxacin has greater activity than ciprofloxacin against pneumococci.

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51. What is the multiplicity expected in the hydrogen NMR spectrum for the hydrogen atoms marked by a "star" in the following compound? 

Explanation

The correct answer is c. The multiplicity expected in the hydrogen NMR spectrum for the hydrogen atoms marked by a "star" in the compound can be determined by looking at the neighboring hydrogen atoms. In this case, the "star" hydrogen atom has two neighboring hydrogen atoms, which means it will exhibit a triplet (3 peaks) in the NMR spectrum.

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52. Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏ 150 mg dailyC ❏ 100 mg dailyD ❏ 50 mg dailyE ❏ 300 mg dailySelect, from A to E, which one of the above corresponds to:diclofenac

Explanation

Diclofenac has a maximum oral daily dose of 150 mg. This means that the highest amount of diclofenac that can be taken orally in a single day is 150 mg. Therefore, the correct answer is B.

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53. Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏ AtroventD ❏ BeconaseE ❏ AlupentSelect, from A to E, which one of the above corresponds to the following presentations: aerosol for inhalation

Explanation

The correct answer is C. Atrovent. Atrovent is an aerosol medication that is used for inhalation.

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54. Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏ AtroventD ❏ BeconaseE ❏ AlupentSelect, from A to E, which one of the above corresponds to the following presentations: spacer device

Explanation

The correct answer is A. The explanation is that AeroChamber is a product that is used as a spacer device. A spacer device is a device that is attached to an inhaler to help improve the delivery of medication to the lungs. It helps to ensure that the medication is properly inhaled and reduces the risk of side effects. Therefore, A is the correct answer as AeroChamber corresponds to the presentation of a spacer device.

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55. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctAntispasmodics that could be recommended for irritable bowelsyndrome include:1 ❏ Colofac2 ❏ Spasmonal3 ❏ Fybogel

Explanation

The correct answer is B because both Colofac and Spasmonal are antispasmodics that could be recommended for irritable bowel syndrome. Fybogel, on the other hand, is a fiber supplement and not an antispasmodic.

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56. Imatinib is an important anticancer drug which targets a protein kinase.The piperazine ring has an important interaction with an amino acid in the binding site. Which amino acid is involved?

Explanation

The piperazine ring of Imatinib has an important interaction with a specific amino acid in the binding site of the protein kinase. This interaction suggests that the amino acid involved must have a complementary structure or charge to interact effectively with the piperazine ring. Among the given options, Glutamic acid is more likely to have this interaction due to its negatively charged side chain, which can form electrostatic interactions with the positively charged piperazine ring. Therefore, Glutamic acid is the most plausible amino acid involved in this interaction.

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57. The following structures show some of the important molecules leading to the discovery of burimamide (B).Which of the following statements concerning burimamide is untrue?

Explanation

Burimamide was not a good antagonist at H2 receptors with weak partial agonist activity.

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58. The following diagram shows development of H2-antagonists from burimamide (structure B). What was the rationale for the introduction of the coloured methyl group?

Explanation

The rationale for the introduction of the coloured methyl group is to introduce an electron donating group on the heterocyclic ring to favor the active tautomer. This means that the methyl group helps stabilize the active form of the molecule, making it more likely to be in its active state and therefore more effective as a H2-antagonist.

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59. Omeprazole is an important proton pump inhibitor. 

Explanation

Omeprazole is considered an important proton pump inhibitor because it helps reduce the production of stomach acid by blocking the enzyme in the stomach wall that produces it. This can be beneficial for individuals who have conditions such as gastroesophageal reflux disease (GERD), stomach ulcers, or excessive stomach acid production. By inhibiting the proton pump, omeprazole helps alleviate symptoms and promote healing in these conditions.

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60. Which of the following compounds would have the highest boiling point? 

Explanation

The compound CH3OH, also known as methanol, would have the highest boiling point among the given options. This is because methanol has strong intermolecular hydrogen bonding between the oxygen atom and the hydrogen atoms. Hydrogen bonding is a strong intermolecular force that requires more energy to break, resulting in a higher boiling point. In contrast, the other compounds do not have hydrogen bonding or have weaker intermolecular forces, leading to lower boiling points.

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61. The following structure is an inhibitor of the enzyme responsible for adding a farnesyl chain to the Ras protein.Which feature binds to the zinc cofactor of the enzyme?

Explanation

The imidazole ring binds to the zinc cofactor of the enzyme.

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62. The following structure is a natural product having anticancer properties, which was isolated from a marine worm.What is it called?

Explanation

Cephalostatin 1 is a natural product isolated from a marine worm that possesses anticancer properties. It is a structure that has been found to have potential in fighting cancer cells.

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63. The following structure is a natural product currently being studied as an anticancer agent.What is the name of the structure? 

Explanation

Depsipeptide is a natural product that is currently being studied as an anticancer agent. It is a compound that contains both peptide and ester bonds, which gives it unique properties and potential therapeutic effects. Researchers are investigating its ability to inhibit cancer cell growth and promote cell death, making it a promising candidate for cancer treatment.

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64. Legionnaires' disease:

Explanation

Legionnaires' disease is characterized by the development of pneumonia. This means that individuals who contract Legionnaires' disease will experience inflammation and infection in their lungs, specifically in the air sacs. This can lead to symptoms such as coughing, difficulty breathing, chest pain, and fever. The disease is caused by a specific type of bacteria called Legionella, which is typically found in water sources such as hot tubs, cooling towers, and plumbing systems. It is not a chronic infectious disease, and its incubation period can range from 2 days to 3 years, during which symptoms may not be present.

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65. Concern the following drugs:A  valaciclovirB  griseofulvinC  itraconazoleE  terbinafineAnswer the question Select, from A to E, which one of the above corresponds to the brand name: Lamisil 

Explanation

The correct answer is E. Terbinafine corresponds to the brand name Lamisil.

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66. Terazosin:

Explanation

Terazosin is a medication that belongs to a class called alpha-1 blockers. It works by relaxing the smooth muscles in the prostate and bladder neck, which helps to improve urine flow and reduce symptoms of an enlarged prostate. Therefore, it is logical to conclude that terazosin increases urinary flow rate.

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67. Concern the following cautionary labels:A ❏ To be sucked or chewed.B ❏ With or after food.C ❏ Follow the printed instructions you have been given with thismedicine.D ❏ Avoid exposure of skin to direct sunlight or sun lamps.E ❏ Do not stop taking this medicine except on your doctor'sadvice.Select, from A to E, which one of the above corresponds to warfarin:

Explanation

The correct answer is C because "Follow the printed instructions you have been given with this medicine" is a cautionary label that would typically be associated with warfarin. This medication requires specific instructions to be followed in order to ensure its effectiveness and to prevent any potential complications.

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68. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctCeftazidime:1 ❏ is a 'third-generation' cephalosporin antibacterial2 ❏ is more active than cefuroxime against Gram-positive bacteria3 ❏ is available as tablets and injections

Explanation

The correct answer is D. Ceftazidime is a 'third-generation' cephalosporin antibacterial. It is only more active than cefuroxime against Gram-positive bacteria. It is available as injections, but not as tablets.

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69. Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏ AtroventD ❏ BeconaseE ❏ AlupentSelect, from A to E, which one of the above corresponds to the following presentations: syrup

Explanation

The correct answer is A. The reason for this is that syrup is a liquid form of medication, and AeroChamber is a device used for inhalation therapy, Nuelin is a tablet used for asthma and chronic obstructive pulmonary disease (COPD), Atrovent is a nasal spray, Beconase is a nasal spray used for allergies, and Alupent is a bronchodilator inhaler. Therefore, A, which is AeroChamber, is the only option that corresponds to the presentation of syrup.

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70. Which of the following alkenes would have the largest lmax?

Explanation

The alkene with the largest lmax would be the one with the highest number of conjugated double bonds. Conjugated double bonds create a larger system of overlapping p-orbitals, which results in a lower energy gap between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO). This lower energy gap corresponds to a longer wavelength of light absorbed, resulting in a larger lmax. Therefore, alkene d, with three conjugated double bonds, would have the largest lmax.

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71. Each of the questions or incomplete statements is followed byfive suggested answers. Select the best answer in each case.All the following products are selective inhibitors of cyclo-oxygenase-2EXCEPT:A ❏ CelebrexB ❏ ArcoxiaC ❏ MobicD ❏ FeldeneE ❏ Prexige

Explanation

The correct answer is D. Feldene. This is because all the other options (Celebrex, Arcoxia, Mobic, and Prexige) are selective inhibitors of cyclo-oxygenase-2, while Feldene is not.

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72. Trigger factors for migraine include all EXCEPT:

Explanation

The trigger factors for migraines can vary from person to person, but some common triggers include certain foods, stress, hormonal changes, and environmental factors. Lack of sleep is often considered a trigger for migraines because it can disrupt the body's natural rhythm and increase stress levels. Therefore, it is surprising that lack of sleep is listed as an exception in this question.

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73. Once activated, the proton pump inhibitors bind to exposed amino acids in the proton pump. Which amino acid is involved?

Explanation

Proton pump inhibitors (PPIs) are medications that work by binding to the proton pump in the stomach, which reduces the production of stomach acid. Once activated, PPIs specifically bind to exposed amino acids in the proton pump. The amino acid involved in this binding process is cysteine.

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74. Which of the following transitions is the highest energy transition?a) n to s*b) n to p*c) s to s*d) p to p* 

Explanation

The transition from s to s is the highest energy transition because electrons in the same energy level (s) have the same energy. Therefore, transitioning between two s orbitals requires the highest amount of energy compared to transitioning between different energy levels or different orbitals within the same energy level.

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75. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctExamples of enzyme inducers include:1 ❏ griseofulvin2 ❏ rifampicin3 ❏ warfarin

Explanation

The correct answer is B because griseofulvin and rifampicin are examples of enzyme inducers. Warfarin, on the other hand, is an example of an enzyme inhibitor.

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76. The following diagram shows development of H2-antagonists from burimamide (structure B).  Why was the cyanide group introduced into structure F (cimetidine)?

Explanation

The cyanide group, being an electron withdrawing group, decreases the basicity of the functional group in structure F (cimetidine). This means that the functional group does not become protonated and remains un-ionized. This is important because H2-antagonists function by blocking the action of histamine on the H2 receptors, which are located on cells in the stomach lining. By remaining un-ionized, the cimetidine molecule can effectively bind to the H2 receptors and inhibit the secretion of gastric acid.

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77. Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏ 150 mg dailyC ❏ 100 mg dailyD ❏ 50 mg dailyE ❏ 300 mg dailySelect, from A to E, which one of the above corresponds to:sildenafil

Explanation

The correct answer is C (100 mg daily). This means that the maximum oral daily dose for sildenafil is 100 mg.

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78. Each of the questions or incomplete statements is followed byfive suggested answers. Select the best answer in each case.Leflunomide:A ❏ its therapeutic effect starts after 4–6 weeksB ❏ is given as an initial dose of 7.5 mgC ❏ is administered once a weekD ❏ is available only for parenteral administrationE ❏ no washout procedures are required when changing toanother product

Explanation

Leflunomide's therapeutic effect starts after 4-6 weeks.

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79. Concern the following drugs:A  valaciclovirB  griseofulvinC  itraconazoleE  terbinafineAnswer the question Select, from A to E, which one of the above corresponds to the brand name: Famvir

Explanation

not-available-via-ai

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80. The tetracyclines act as intercalating anticancer agents.Which of the following is a simplified analogue of tetracyclines?

Explanation

Mitoxantrone is a simplified analogue of tetracyclines because it also acts as an intercalating anticancer agent. Intercalating agents are molecules that can insert themselves between the DNA base pairs, disrupting DNA replication and causing cell death. Tetracyclines, a class of antibiotics, have been found to have anticancer properties due to their intercalating ability. Mitoxantrone, a chemotherapeutic agent, has a similar mechanism of action and is used in the treatment of various cancers. Therefore, Mitoxantrone is a simplified analogue of tetracyclines.

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81. Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏ imipramineD ❏ carbamazepineE ❏ co-trimoxazoleSelect, from A to E, during pregnancy which one of the above:may cause intrauterine growth restriction

Explanation

Atenolol is a beta-blocker medication commonly used to treat high blood pressure and certain heart conditions. However, it has been associated with an increased risk of intrauterine growth restriction (IUGR) when used during pregnancy. IUGR refers to a condition where the fetus does not grow at a normal rate, leading to a smaller than average size at birth. This can have potential negative effects on the baby's health and development. Therefore, it is important to avoid using atenolol during pregnancy unless the benefits outweigh the risks and under the guidance of a healthcare professional.

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82. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctAntacid preparations containing sodium bicarbonate include:1 ❏ Gaviscon liquid2 ❏ Bisodol Heartburn Relief tablets3 ❏ Maalox Plus tablets

Explanation

The correct answer is B because both Gaviscon liquid and Bisodol Heartburn Relief tablets contain sodium bicarbonate, while Maalox Plus tablets do not.

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83. Which of the following products is NOT indicated for the management of peptic ulceration?

Explanation

Buscopan is not indicated for the management of peptic ulceration because it is an antispasmodic medication that is primarily used to relieve smooth muscle spasms in the gastrointestinal tract. It does not have any direct effect on reducing acid production or protecting the stomach lining, which are the primary goals in managing peptic ulceration. On the other hand, Gaviscon, Nexium, and Pariet are commonly used in the management of peptic ulceration as they help reduce stomach acid production or provide a protective barrier for the stomach lining.

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84. Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏ AtroventD ❏ BeconaseE ❏ AlupentSelect, from A to E, which one of the above corresponds to the following presentations: nasal spray

Explanation

The correct answer is D. Beconase. The question asks for the product that corresponds to the presentation of a nasal spray. Beconase is a nasal spray used for treating allergies and nasal congestion.

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85. Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏ levofloxacinD ❏ ofloxacinE ❏ amphotericinSelect, from A to E, which one of the above:Drug which is marketed as Tavanic

Explanation

Levofloxacin is marketed as Tavanic.

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86. Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏ 150 mg dailyC ❏ 100 mg dailyD ❏ 50 mg dailyE ❏ 300 mg dailySelect, from A to E, which one of the above corresponds to:sumatriptan

Explanation

The maximum oral daily dose for sumatriptan is 300 mg.

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87. The following stereoisomers are related as...

Explanation

Epimers are a type of stereoisomers that differ in the configuration of only one stereogenic center. In this case, the compounds being referred to are likely isomers with multiple chiral centers, and they differ in the configuration of one of those centers. Therefore, the correct answer is epimers.

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88. Tambocor:

Explanation

Tambocor may be of value in serious symptomatic ventricular arrhythmias. This means that Tambocor could be beneficial in treating severe and symptomatic irregular heartbeats that originate in the ventricles of the heart. It suggests that Tambocor has potential effectiveness in managing this specific type of cardiac condition.

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89. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctWhich of the following drugs may be used in patients with liver diseasebut require a dose reduction?1 ❏ Natrilix2 ❏ Nizoral3 ❏ Zyloric

Explanation

The correct answer is E. Only option 3, Zyloric, may be used in patients with liver disease but requires a dose reduction. Natrilix (option 1) is contraindicated in patients with severe liver disease, and Nizoral (option 2) is not recommended in patients with liver disease due to its potential for hepatotoxicity. Therefore, options 1 and 2 are not correct.

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90. How many dichlorinated isomers can be formed by the halogenation of CH3CH2CH2CH3 with Cl2 in the presence of light? 

Explanation

When CH3CH2CH2CH3 reacts with Cl2 in the presence of light, the halogenation reaction can occur at any of the four carbon atoms. Each carbon atom can be either primary or secondary, resulting in different isomers. Since there are four carbon atoms, and each carbon atom can have two possible isomers, the total number of dichlorinated isomers formed is 2^4 = 16. However, since the molecule is symmetrical, some of these isomers are identical. After removing the duplicate isomers, we are left with 6 unique dichlorinated isomers.

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91. Each of the questions or incomplete statements is followed byfive suggested answers. Select the best answer in each case.What is an appropriate therapeutic alternative for Pulmicort?A ❏ ZaditenB ❏ BecotideC ❏ IntalD ❏ AtroventE ❏ Serevent

Explanation

Becotide is an appropriate therapeutic alternative for Pulmicort. This is because both Pulmicort and Becotide are inhaled corticosteroids that are used to treat asthma and other respiratory conditions. They work by reducing inflammation in the airways and improving breathing. Therefore, Becotide can be a suitable substitute for Pulmicort in managing respiratory symptoms.

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92. Which of the Fischer projections correctly depicts the following compound? 

Explanation

not-available-via-ai

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93. Which of the following compounds exhibit optical activity?

Explanation

Compound d exhibits optical activity because it contains a chiral center. Optical activity refers to the ability of a compound to rotate the plane of polarized light. A chiral center is a carbon atom bonded to four different groups. In compound d, there is a chiral carbon atom, indicated by the asterisk (*), which means it has two different mirror image forms. This chirality allows compound d to exhibit optical activity.

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94. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctPotentially hazardous interactions could occur between:1 ❏ ergotamine and zolmitriptan2 ❏ warfarin and gliclazide3 ❏ combined oral contraceptives and clindamycin

Explanation

The correct answer is B because it states that only options 1 and 2 are correct. This means that potentially hazardous interactions could occur between ergotamine and zolmitriptan, as well as warfarin and gliclazide. Option 3, which suggests that combined oral contraceptives and clindamycin could have hazardous interactions, is not correct according to the given answer.

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95. A parent requests a multivitamin preparation for a 6-year-old child.Which product could be recommended?A ❏ ForcevalB ❏ VivioptalC ❏ MaxepaD ❏ En-De-KayE ❏ Calcium-Sandoz

Explanation

Forceval could be recommended as a multivitamin preparation for a 6-year-old child.

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96. Hat is the lmax for the following compound? Use the provided parameters for your calculation. 

Explanation

The lmax for a compound refers to the wavelength at which it absorbs light most strongly. In this case, the correct answer is 283 nm, indicating that the compound absorbs light most strongly at this wavelength. The provided parameters likely include information about the compound's structure and electronic properties, which determine its absorption characteristics.

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97. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctParadichlorobenzene:1 ❏ has antifungal properties2 ❏ is used as a disinfectant3 ❏ is present in Cerumol drops

Explanation

The correct answer is E. The explanation is that Paradichlorobenzene is present in Cerumol drops. It does not have antifungal properties and is not used as a disinfectant.

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98. Directions: For each of the questions below, ONE or MORE of theresponses is (are) correct. Decide which of the responses is(are) correct. Then choose:A ❏ if 1, 2 and 3 are correctB ❏ if 1 and 2 only are correctC ❏ if 2 and 3 only are correctD ❏ if 1 only is correctE ❏ if 3 only is correctMale pattern baldness:1 ❏ is androgenetic alopecia2 ❏ is caused by the release of prostaglandins3 ❏ may be precipitated by chemical hair preparations

Explanation

The correct answer is D.

Male pattern baldness, also known as androgenetic alopecia, is the correct response for statement 1. Statement 2, which states that male pattern baldness is caused by the release of prostaglandins, is incorrect. Statement 3, which suggests that chemical hair preparations may precipitate male pattern baldness, is also incorrect. Therefore, only statement 1 is correct.

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99. A patient asks for ibuprofen gel. The pharmacist may dispense:A ❏ OruvailB ❏ VoltarolC ❏ DubamD ❏ BrufenE ❏ Ibutop

Explanation

The correct answer is A. Oruvail. This is because Oruvail is a brand name for ibuprofen gel, which is what the patient requested. Voltarol, Dubam, Brufen, and Ibutop are all different brands or types of medications and may not contain ibuprofen gel.

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100. Each of the questions or incomplete statements is followed by five suggested answers. Select the best answer in each case.Raynaud's phenomenon: A ❏ is characterised by vasodilation B ❏ causes hot, red feet C ❏ starts as white patches of skin D ❏ is caused by a bacterial infection E ❏ may require vasodilator treatment

Explanation

Raynaud's phenomenon is a condition characterized by vasospasm, which causes narrowing of the blood vessels in the extremities, usually the fingers and toes. This leads to decreased blood flow and can result in color changes in the skin, starting with white patches (pallor) due to lack of blood flow, followed by blue (cyanosis) and then red (rubor) as blood flow returns. Treatment for Raynaud's phenomenon may involve the use of vasodilators to help relax and widen the blood vessels, improving blood flow and reducing symptoms.

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Which of the following alkenes would have the largest lmax?
Which microorganism has been associated with the appearance of ulcers?
What is the total number of sigma bonds found in the following...
The following diagram shows development of H2-antagonists from...
Good pharmacy practice guidelines:
Directions: For each of the questions below, ONE or MORE of...
The most stable conformational isomer of...
Anti-D immunoglobulin:
Which of the following alkanes would have the highest boiling point?
How are the following compounds related?
The following structures show some of the important molecules leading...
Directions: For each of the questions below, ONE or MORE of...
Which Newman projection shows the most stable conformation of the...
Which of the these compounds represents the major monochlorination...
What is the major product of the following reaction?
Concern the following drugs:A  valaciclovirB  griseofulvinC...
To what extent are the three nitrogens of histamine ionised at blood...
What is the IUPAC name for the following compound?
Which of the following inhibits angiogenesis?
Which of the following nuclei will have a magnetic moment?
What is the lmax for the following compound? Use the below parameters...
A mother requests a preparation for her 5-year-old son for a...
Three binding regions were proposed to be present in the binding site...
Directions: For each of the questions below, ONE or MORE of...
What bacterial enzyme aids the survival of Helicobacter...
What is the total number of pi bonds found in the following compound?
What is the IUPAC name for the following compound?
What is the name of the following anticancer drug?
The CMR spectrum of an unknown compound shows 4 absorptions and the...
Concern the following cautionary labels:A ❏ To be sucked or chewed.B...
Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏...
Which is an alternative preparation of Lipitor?
The CMR spectrum of an unknown compound shows 6 absorptions and the...
Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏...
What is the name of the following anticancer drug? 
The following structure is called marimastat and is a matrix...
Directions: For each of the questions below, ONE or MORE of...
The following diagram shows development of H2-antagonists from...
Two regions of cimetidine are susceptible to metabolism. Which...
The following mechanism shows how proton pump inhibitors are...
Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏...
Concern the following cautionary labels:A ❏ To be sucked or chewed.B...
Directions: For each of the questions below, ONE or MORE of...
All the following products used in the treatment of glaucoma are...
Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏...
Pentostatin is a natural product used for the treatment...
All the following products contain a local anaesthetic EXCEPT:
The following diagram shows various conformations for the...
The most stable conformational isomer of...
Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏...
What is the multiplicity expected in the hydrogen NMR spectrum for the...
Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏...
Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏...
Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏...
Directions: For each of the questions below, ONE or MORE of...
Imatinib is an important anticancer drug which targets a protein...
The following structures show some of the important molecules leading...
The following diagram shows development of H2-antagonists from...
Omeprazole is an important proton pump inhibitor. 
Which of the following compounds would have the highest boiling...
The following structure is an inhibitor of the enzyme responsible for...
The following structure is a natural product having anticancer...
The following structure is a natural product currently being studied...
Legionnaires' disease:
Concern the following drugs:A  valaciclovirB  griseofulvinC...
Terazosin:
Concern the following cautionary labels:A ❏ To be sucked or chewed.B...
Directions: For each of the questions below, ONE or MORE of...
Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏...
Which of the following alkenes would have the largest lmax?
Each of the questions or incomplete statements is followed byfive...
Trigger factors for migraine include all EXCEPT:
Once activated, the proton pump inhibitors bind to exposed amino acids...
Which of the following transitions is the highest energy...
Directions: For each of the questions below, ONE or MORE of...
The following diagram shows development of H2-antagonists from...
Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏...
Each of the questions or incomplete statements is followed byfive...
Concern the following drugs:A  valaciclovirB  griseofulvinC...
The tetracyclines act as intercalating anticancer agents.Which of the...
Concern the following drugs:A ❏ atenololB ❏ folic acidC ❏...
Directions: For each of the questions below, ONE or MORE of...
Which of the following products is NOT indicated for the...
Concern the following products:A ❏ AeroChamberB ❏ NuelinC ❏...
Concern the following drugs:A ❏ nalidixic acidB ❏ norfloxacinC ❏...
Concern the following maximum oral daily doses:A ❏ 200 mg dailyB ❏...
The following stereoisomers are related as...
Tambocor:
Directions: For each of the questions below, ONE or MORE of...
How many dichlorinated isomers can be formed by the halogenation of...
Each of the questions or incomplete statements is followed byfive...
Which of the Fischer projections correctly depicts the following...
Which of the following compounds exhibit optical activity?
Directions: For each of the questions below, ONE or MORE of...
A parent requests a multivitamin preparation for a 6-year-old...
Hat is the lmax for the following compound? Use the provided...
Directions: For each of the questions below, ONE or MORE of...
Directions: For each of the questions below, ONE or MORE of...
A patient asks for ibuprofen gel. The pharmacist may dispense:A ❏...
Each of the questions or incomplete statements is followed by...
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