Neurology Drx - Movement Disorders And Associated Pharmacology

21 Questions | By Exceldoc | Last updated: Mar 22, 2022 | Total Attempts: 105

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1.

How would you treat generalized dystonia (Recall that a generalized dystonia is multifocal and involves several body parts?)
2.

Which pharmacologic therapies can be used for Huntington’s?
3.

What is the clinical term of the movement she is describing?
4.

At the onset of PD symptoms, approximately ____% of dopamine neurons are lost?
5.

What drug is thought to reduce the progression of Parkinson Disease?
6.

This class of drugs, used to treat PD has the unfortunate side effects of nausea/vomiting, hallucinations, psychosis, orthostatic hypotension and psychosis ______________
7.

From the list below, select the four cardinal motor features/sx of Parkinson’s Disease.
- A.
  
  Postural Instability (shuffling gait, stooped stance)
- B.
  
  Masked facies
- C.
  
  Bradykinesia
- D.
  
  Resting Tremor (aka pill rolling tremor)
- E.
  
  Dystonia
- F.
  
  Essential tremor
- G.
  
  Rigidity
8.

_________________ is a drug currently used to treat to PD, but was previously used as an antimicrobial agent.
9.

What is the most common movement disorder? (Questions 9 -14 are based on the answer to this question)
10.

The condition in question #8 is a(n) ____________ tremor.
11.

ET is known to most commonly affect the head, upper extremeties and __________________
12.

True of False: ET is responsive to anti-PD drugs.
- A.
  
  True
- B.
  
  False
13.

Classically ET abates with ______________consumption (Hint: it is a non-pharmacologic agent)
14.

Which of the following pharmacologic agents are typically used to treat ET?
- A.
  
  Benzodiazepines
- B.
  
  Antipsychotics
- C.
  
  Vigabitrin
- D.
  
  Topiramate
- E.
  
  Propanalol
- F.
  
  Clozapine
- G.
  
  Primidone
- H.
  
  Carbamazepine
15.

DBT (deep brain stimulation therapy) can be used to treat severe forms of ET by targeting this (an organ)__________ in the CNS.
16.

Questions 15-21 are based on the following scenario: 30 yr old woman somes to your office with complaints of involuntary limb movements. Her partner also states that she hasn’t been herself lately, like her personality is changing. Her mother died in her 40s due to a neurologic disorder. What is your leading diagnosis?
17.

Imaging studies of her brain will show atrophy of what CNS structures?
- A.
  
  Thalamus
- B.
  
  Cortex
- C.
  
  Putamen
- D.
  
  Globus Pallidus
- E.
  
  Caudate
- F.
  
  Myelin
18.

Assuming this is a hereditary disease, how is it passed on?
19.

The mutation responsible for this disease is found on what chromosome _____ (a number)?
20.

This disease involves a trinucleotide repeat. Which sequence is involved?
- A.
  
  CCG
- B.
  
  CAG
- C.
  
  CGG
- D.
  
  GAC
21.

There is a pharmacologic cure for Huntington's Disease.
- A.
  
  True
- B.
  
  False