Path 3610: Principles Of Disease Quiz! Test

114 Questions | Total Attempts: 822

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Path 3610: Principles Of Disease Quiz! Test - Quiz

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Questions and Answers
  • 1. 
    Increased vascular permeability in inflammation will allow large protein molecules to leave the vascular space. These include:
    • A. 

      Albumin

    • B. 

      Fibrinogen

    • C. 

      Urea

  • 2. 
    Neutrophils leave capillaries in inflammation by the process of:
    • A. 

      Diapedesis

    • B. 

      Phagocytosis

    • C. 

      Margination

    • D. 

      Option 4

  • 3. 
    Neutrophil diapedesis is assisted by:
    • A. 

      Enlarged endothelial pores

    • B. 

      Digestive enzymes

    • C. 

      Increased phagocytic ability

    • D. 

      Option 4

  • 4. 
    Inflammatory cell movement into an area of acute inflammation is a passive process.
    • A. 

      True

    • B. 

      False

    • C. 

      Option 3

    • D. 

      Option 4

  • 5. 
    Which of the following statements about fibrin is false?
    • A. 

      It is an insoluble polymer

    • B. 

      It is one of the constituents of scar tissue

    • C. 

      It is formed from fibrinogen, through the action of thrombin

    • D. 

      Option 4

  • 6. 
    A primary function of neutrophils is:
    • A. 

      Phagocytosis of microorganisms

    • B. 

      Secretion of complement components

    • C. 

      Production of endogenous pyrogen

    • D. 

      Option 4

  • 7. 
    The marked active dilation of vessels in acute inflammation is due to:
    • A. 

      Reflex neural mechanisms

    • B. 

      The effects of kinins

    • C. 

      Release of chemical mediators by damaged cells

    • D. 

      Option 4

  • 8. 
    The mononuclear cell type with the greatest role in acute inflammation is the:
    • A. 

      Monocyte

    • B. 

      Plasma cell

    • C. 

      Macrophage

    • D. 

      Option 4

  • 9. 
    The synthesis of arachidonic acid metabolites is increased at inflammatory sites.
    • A. 

      True

    • B. 

      False

    • C. 

      Option 3

    • D. 

      Option 4

  • 10. 
    The process by which inflammatory cells are attracted to an area of injury by directional migration along a chemical concentration gradient is termed:
    • A. 

      Emesis

    • B. 

      Diapedesis

    • C. 

      Chemotaxis

    • D. 

      Option 4

  • 11. 
    Transudates are basically an ultrafiltrate of plasma.
    • A. 

      True

    • B. 

      False

    • C. 

      Option 3

    • D. 

      Option 4

  • 12. 
    Plasma cells secrete:
    • A. 

      Albumin

    • B. 

      Plasma proteins

    • C. 

      Antibody

    • D. 

      Option 4

  • 13. 
    Vaccination is used to produce immunity against infectious organisms, by inducing:
    • A. 

      Passive immunity

    • B. 

      The secondary immune response

    • C. 

      The primary immune response

    • D. 

      Option 4

  • 14. 
    The lack of response to our own antigens is termed:
    • A. 

      Anergy

    • B. 

      Self tolerance

    • C. 

      Immunogenicity

    • D. 

      Option 4

  • 15. 
    Sites of lymphocyte priming are the:
    • A. 

      Spleen and tonsils

    • B. 

      Peripheral lymph nodes

    • C. 

      Thymus and bone marrow

    • D. 

      Option 4

  • 16. 
    Amplification or expansion of the immune response is characteristic of:
    • A. 

      The B cell response to antigen

    • B. 

      The T cell response to antigen

    • C. 

      Both of the above

    • D. 

      Option 4

  • 17. 
    Complete the following statement correctly: Macrophages:
    • A. 

      Are found only in certain tissues of the body

    • B. 

      Secrete cytokines which can influence both T and B cell function

    • C. 

      Express immunoglobulins on their surfaces

    • D. 

      Option 4

  • 18. 
    Lymph nodes which are enlarged because of response to an antigenic stimulus are termed:
    • A. 

      Reactive

    • B. 

      Edematous

    • C. 

      Hypertrophic

    • D. 

      Option 4

  • 19. 
    The profound immunosuppression associated with AIDS is primarily associated with defective:
    • A. 

      Humoral immunity

    • B. 

      Cell-mediated immunity

    • C. 

      Macrophage function

    • D. 

      Option 4

  • 20. 
    The term serology refers to the study of:
    • A. 

      Serum chemistry

    • B. 

      The body reaction to infectious disease

    • C. 

      Antigen-antibody reactions in a laboratory setting

    • D. 

      Option 4

  • 21. 
    Molecules which evoke an immune response when introduced into a host are termed:
    • A. 

      Antigens

    • B. 

      Haptens

    • C. 

      Pathogens

    • D. 

      Option 4

  • 22. 
    In Type II (antibody-dependent) hypersensitivity, antibody is:
    • A. 

      Bound to mast cell surfaces

    • B. 

      Directed against specific antigens on cell surfaces

    • C. 

      Bound to antigen to form free immune complexes

    • D. 

      Option 4

  • 23. 
    Theories on the development of auto-immunity describe:
    • A. 

      Excessive lymphocyte clonal deletion during embryonic development

    • B. 

      Excessive suppressor T-cell activity

    • C. 

      Reaction against slightly altered tissue components

    • D. 

      Option 4

  • 24. 
    A primary characteristic of the immune response is its:
    • A. 

      Role as a defense mechanism

    • B. 

      Specificity

    • C. 

      Ability to fight infectious disease

    • D. 

      Option 4

  • 25. 
    Macrophages and monocytes act as important reservoirs and producers of HIV.
    • A. 

      True

    • B. 

      False