Path 3610: Principles Of Disease Quiz! Test

114 Questions | By Leviy.elhadad | Last updated: Mar 22, 2022 | Total Attempts: 822

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Path 3610: Principles Of Disease Quiz! Test - Quiz

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1.

Increased vascular permeability in inflammation will allow large protein molecules to leave the vascular space. These include:
- A.
  
  Albumin
- B.
  
  Fibrinogen
- C.
  
  Urea
2.

Neutrophils leave capillaries in inflammation by the process of:
- A.
  
  Diapedesis
- B.
  
  Phagocytosis
- C.
  
  Margination
- D.
  
  Option 4
3.

Neutrophil diapedesis is assisted by:
- A.
  
  Enlarged endothelial pores
- B.
  
  Digestive enzymes
- C.
  
  Increased phagocytic ability
- D.
  
  Option 4
4.

Inflammatory cell movement into an area of acute inflammation is a passive process.
- A.
  
  True
- B.
  
  False
- C.
  
  Option 3
- D.
  
  Option 4
5.

Which of the following statements about fibrin is false?
- A.
  
  It is an insoluble polymer
- B.
  
  It is one of the constituents of scar tissue
- C.
  
  It is formed from fibrinogen, through the action of thrombin
- D.
  
  Option 4
6.

A primary function of neutrophils is:
- A.
  
  Phagocytosis of microorganisms
- B.
  
  Secretion of complement components
- C.
  
  Production of endogenous pyrogen
- D.
  
  Option 4
7.

The marked active dilation of vessels in acute inflammation is due to:
- A.
  
  Reflex neural mechanisms
- B.
  
  The effects of kinins
- C.
  
  Release of chemical mediators by damaged cells
- D.
  
  Option 4
8.

The mononuclear cell type with the greatest role in acute inflammation is the:
- A.
  
  Monocyte
- B.
  
  Plasma cell
- C.
  
  Macrophage
- D.
  
  Option 4
9.

The synthesis of arachidonic acid metabolites is increased at inflammatory sites.
- A.
  
  True
- B.
  
  False
- C.
  
  Option 3
- D.
  
  Option 4
10.

The process by which inflammatory cells are attracted to an area of injury by directional migration along a chemical concentration gradient is termed:
- A.
  
  Emesis
- B.
  
  Diapedesis
- C.
  
  Chemotaxis
- D.
  
  Option 4
11.

Transudates are basically an ultrafiltrate of plasma.
- A.
  
  True
- B.
  
  False
- C.
  
  Option 3
- D.
  
  Option 4
12.

Plasma cells secrete:
- A.
  
  Albumin
- B.
  
  Plasma proteins
- C.
  
  Antibody
- D.
  
  Option 4
13.

Vaccination is used to produce immunity against infectious organisms, by inducing:
- A.
  
  Passive immunity
- B.
  
  The secondary immune response
- C.
  
  The primary immune response
- D.
  
  Option 4
14.

The lack of response to our own antigens is termed:
- A.
  
  Anergy
- B.
  
  Self tolerance
- C.
  
  Immunogenicity
- D.
  
  Option 4
15.

Sites of lymphocyte priming are the:
- A.
  
  Spleen and tonsils
- B.
  
  Peripheral lymph nodes
- C.
  
  Thymus and bone marrow
- D.
  
  Option 4
16.

Amplification or expansion of the immune response is characteristic of:
- A.
  
  The B cell response to antigen
- B.
  
  The T cell response to antigen
- C.
  
  Both of the above
- D.
  
  Option 4
17.

Complete the following statement correctly: Macrophages:
- A.
  
  Are found only in certain tissues of the body
- B.
  
  Secrete cytokines which can influence both T and B cell function
- C.
  
  Express immunoglobulins on their surfaces
- D.
  
  Option 4
18.

Lymph nodes which are enlarged because of response to an antigenic stimulus are termed:
- A.
  
  Reactive
- B.
  
  Edematous
- C.
  
  Hypertrophic
- D.
  
  Option 4
19.

The profound immunosuppression associated with AIDS is primarily associated with defective:
- A.
  
  Humoral immunity
- B.
  
  Cell-mediated immunity
- C.
  
  Macrophage function
- D.
  
  Option 4
20.

The term serology refers to the study of:
- A.
  
  Serum chemistry
- B.
  
  The body reaction to infectious disease
- C.
  
  Antigen-antibody reactions in a laboratory setting
- D.
  
  Option 4
21.

Molecules which evoke an immune response when introduced into a host are termed:
- A.
  
  Antigens
- B.
  
  Haptens
- C.
  
  Pathogens
- D.
  
  Option 4
22.

In Type II (antibody-dependent) hypersensitivity, antibody is:
- A.
  
  Bound to mast cell surfaces
- B.
  
  Directed against specific antigens on cell surfaces
- C.
  
  Bound to antigen to form free immune complexes
- D.
  
  Option 4
23.

Theories on the development of auto-immunity describe:
- A.
  
  Excessive lymphocyte clonal deletion during embryonic development
- B.
  
  Excessive suppressor T-cell activity
- C.
  
  Reaction against slightly altered tissue components
- D.
  
  Option 4
24.

A primary characteristic of the immune response is its:
- A.
  
  Role as a defense mechanism
- B.
  
  Specificity
- C.
  
  Ability to fight infectious disease
- D.
  
  Option 4
25.

Macrophages and monocytes act as important reservoirs and producers of HIV.
- A.
  
  True
- B.
  
  False