Pharmacology - Pituitary, Adrenal Treatment
- 1.What medication is used in the treatment of Growth Hormone deficiency?
- A.
Somatropin
- B.
Somatostatin analogs
- C.
Dopamine agonists
- D.
Glucocorticoids
- 2.What medication is used in the treatment of Growth hormone excess?
- A.
Dopamine agonists
- B.
Somatropin
- C.
Somatostatin analogs
- D.
Mineralocorticoids
- 3.What medication is used in the treatment of Hyperprolactinemia?
- A.
Somatostatin analogs (Octreotide and lanreotide)
- B.
Dopamine agonists (Bromocriptine (Parlodel)
- C.
Somatropin
- 4.Hyperprolactinemia inhibits GnRH secretion causes what clinical features and symptoms in women?
- A.
Amenorrhea
- B.
Infertility
- C.
Galactorrhea
- D.
Low libido
- 5.True or False: The most common etiologies of Hyperprolactinemia are prolactin-secreting adenomas and medications like SSRIs, haloperidol, metoclopramide, dopamine antagonists.
- A.
True
- B.
False
- 6._______________ regulate sodium and potassium reabsorption in the collecting tubules of the kidney
- 7.Select all: What are the clinical Uses of Corticosteroids?
- A.
Diagnosis and treatment of adrenal dysfunction
- B.
Replacement in adrenal insufficiency (acute and/or chronic)
- C.
Numerous uses- r/t ability to suppress inflammatory & immune responses
- D.
Stimulation of lung maturation in the fetus
- 8.Which test is used for diagnosis of Addison’s disease
- A.
Dexamethasone suppression test
- B.
Short cosyntropin-stimulation test
- 9.Which test is used in the Diagnosis of Cushing syndrome?
- A.
Dexamethasone suppression test
- B.
Short cosyntropin-stimulation test
- 10.Select all that apply: Signs and Symptoms of Adrenal Insufficiency
- A.
Fatigue
- B.
Anorexia
- C.
Weight gain
- D.
Nausea
- E.
Constipation
- F.
Hyperglycemia
- G.
Hyperkalemia
- H.
Hyperkalemia
- I.
Salt cravings
- J.
Salt cravings
- 11.Select all that apply: What medications are used in the treatment of Adrenal Insufficiency (Addison Disease)?
- A.
Glucocorticoids
- B.
Corticosteroids
- C.
Mineralocorticoid
- 12.In Addison's disease, a person will retain too much?
- A.
Calcium
- B.
Sodium
- C.
Chloride
- D.
Potassium
- 13.Select the side effects of Hydrocortisone treatment
- A.
Hyperglycemia
- B.
hypertension
- C.
Hyperkalemia
- D.
Sodium retention
- 14.Hypercortisolism (Cushing syndrome) is clinical condition resulting from chronic exposure to excessive circulating levels of glucocorticoids
- A.
True
- B.
False
- 15.Select one: ALL are used in the treatment of Cushing Syndrome but which is the most desired?
- A.
Surgical removal of ACTH producing tumor
- B.
Irradiation of pituitary tumor
- C.
Steroidogenesis inhibitors
- D.
Adrenolytic agents
- E.
Neuromodulators of ACTH release
- F.
Glucocorticoid receptor antagonist
- 16.____________________ promotes reabsorption of sodium from renal tubules.
- 17.Select all: Hyperaldosteronism- Excessive levels of aldosterone (produced by tumors or overdosage with synthetic mineralocorticoids) leads to...
- A.
Hypokalemia,
- B.
Metabolic alkalosis
- C.
Increased plasma volume
- D.
Hypertension
- 18.____________________ is a potent steroid w/ glucocorticoid & mineralocorticoid activity
- 19.Fludrocortisone is the most widely used agent in the treatment of adrenocortical insufficiency associated w/ mineralocorticoid deficiency
- A.
True
- B.
False
- 20.Treatment of adrenal insufficiency
- A.
Hydrocortisone
- B.
Fludrocortisone
- 21.Fludrocortisone is also used for orthostatic hypotension
- A.
True
- B.
False
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