Pharmacology- Endocrine -thyroid Treatment

19 Questions | Total Attempts: 163

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Pharmacology- Endocrine -thyroid Treatment - Quiz

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Questions and Answers
  • 1. 
    Hypothyroidism usually requires a lifelong hormone replacement, what is the drug of choice for this condition?
    • A. 

      Radioactive iodine

    • B. 

      Levothyroxine

    • C. 

      Thioamides

    • D. 

      Iodides

  • 2. 
    What is Myxedema?
    • A. 

      Irreversible mental retardation and dwarfism caused by congenital hypothyroidism

    • B. 

      Severe hypothyroidism

    • C. 

      Enlargement of the thyroid gland

    • D. 

      Autoimmune disorder that results in hyperthyroidism

  • 3. 
    You as the NP is having a follow-up visit with a patient that you started on Levothyroxine approximately 1 month ago and you review the patients labs, the labs reveal elevated TSH. What could the elevated TSH indicate, what should you do FIRST? 
    • A. 

      Assess for malabsoprtion, diarrhea

    • B. 

      Decrease dosage

    • C. 

      Assess for Angina

    • D. 

      Increase dosage

  • 4. 
    You know your patient understood the teaching about his medication Levothyroxine when the patient states... 
    • A. 

      "It's okay to switch brands, there is no difference in absorption"

    • B. 

      "I should avoid taking my Iron and calcium supplements at the same time as I take my Levothyroxine"

    • C. 

      "After one year of taking my Levothyroxine, my thyroid will be back to normal"

    • D. 

      " I should take my medication on an empty stomach in the morning or at bedtime"

  • 5. 
    What is the recommendation for Thyroid function monitoring with any changes in preparations? 
    • A. 

      4- 6 weeks

    • B. 

      6-8 weeks

    • C. 

      2-3 weeks

    • D. 

      8-10 weeks

  • 6. 
    What are some causes of Hypothyroidism with Goiter?
    • A. 

      Peripheral resistance to thyroid hormone

    • B. 

      Drugs like Lithium & amiodarone

    • C. 

      Iodine elevated

    • D. 

      Toxic adenoma

    • E. 

      Hashimoto thyroiditis

    • F. 

      Hepatitis C

    • G. 

      Autoimmune disorder

  • 7. 
    Select all that apply: As a NP, you know the the clinical signs of Hypothyroidism are 
    • A. 

      Bradycardia

    • B. 

      Nervousness, irritability,

    • C. 

      Palpably enlarged thyroid (goiter)

    • D. 

      Skin pallor or yellowing (carotenemia)

    • E. 

      Peripheral edema, puffy face and eyelids

    • F. 

      Tremor, hyperreflexia

    • G. 

      Dry, pale skin

  • 8. 
    What lab values would be consistent with the diagnosis of HYPOthyroidism? 
    • A. 

      T4- Low T3- Low TSH- High

    • B. 

      T4- High T3- High TSH- Low

    • C. 

      T4- Low T3- High TSH- Normal

  • 9. 
    What are some causes of HYPERthyroidism? 
    • A. 

      Hashimoto thyroiditis

    • B. 

      Toxic diffuse goiter (Graves disease)

    • C. 

      Toxic adenoma

    • D. 

      Peripheral resistance to thyroid hormone

    • E. 

      Genetic thyroid enzyme defects

  • 10. 
    True or False: Hyperthyroidism is a hypermetabolic state resulting from excess thyroid hormone and affects 2% of women and 0.2% of men in their lifetimes. 
    • A. 

      True

    • B. 

      False

  • 11. 
    What are some clinical features in Thyrotoxicosis (hyperthyroidism)? 
    • A. 

      Nervousness, irritability

    • B. 

      Cool dry skin

    • C. 

      Tachycardia, arrhythmias

    • D. 

      Heat intolerance, increased perspiration

    • E. 

      Decreased appetite

    • F. 

      Goiter

  • 12. 
    What would the lab values look like in Hyperthyroidism? 
    • A. 

      Suppressed TSH and elevated T3 & T4

    • B. 

      Elevated TSH and suppressed T3 & T4

  • 13. 
    Select all: What medications are used in a patient with HYPERthyroidism?
    • A. 

      Thioamides

    • B. 

      Levothyroxine

    • C. 

      Somostatin Analogs

    • D. 

      Iodides

    • E. 

      Propanolol

  • 14. 
    True or false: Methimazole is the first-line Rx in children, adolescents, and pregnancy with HYPERthyroidism. 
    • A. 

      True

    • B. 

      False

  • 15. 
    What is the MOA of Thioamides (Methimazole and PTU)? 
    • A. 

      Inhibits iodine organification & hormone release

    • B. 

      Inhibit cell-mediated immunologic functions

    • C. 

      Inhibit thyroid peroxidase reactions, iodine organification, and peripheral conversion of T4 to T3 (prevent hormone synthesis)

  • 16. 
    Select all: What are some ADE's of Thioamides (Methimazole & PTU)?
    • A. 

      GI symptoms, Nausea,

    • B. 

      Rash

    • C. 

      Agranulocytosis

    • D. 

      Hypothyroidism

    • E. 

      Edema

    • F. 

      Hepatitis

  • 17. 
    What medication class is used in hyperthyroidism as a supportive therapy?
    • A. 

      Ace inhibitors

    • B. 

      Beta blockers

    • C. 

      Calcium channel blockers

    • D. 

      Alpha Blockers

  • 18. 
    Your patient is in the first trimester of her pregnancy, what treatment is best for her to start for HYPERthyroidism? 
    • A. 

      Methimazole

    • B. 

      Radioiodine

    • C. 

      Propylthiouracil (PTU)

    • D. 

      Subtotal thyroidectomy

  • 19. 
    This Thioamide is the drug of choice during thyroid storm  
    • A. 

      Propylthiouracil (PTU)

    • B. 

      Methimazole

    • C. 

      Propanolol

    • D. 

      Iodine

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