Effects Of Insulin And Glucagon! Biochemistry Trivia Quiz

68 Questions | Total Attempts: 1156

SettingsSettingsSettings
Effects Of Insulin And Glucagon! Biochemistry Trivia Quiz - Quiz

.


Questions and Answers
  • 1. 
    What cells in the pancreas release insulin?
    • A. 

      Pancreatic Alpha cell

    • B. 

      Pancreatic Beta cell

    • C. 

      Parietal cells

    • D. 

      Mucous cells

  • 2. 
    In the pancreatic beta-cell:
    • A. 

      Preproinsulin is processed to pronsulin and then to insulin that is secreted

    • B. 

      Proinsulin is processed to insulin and then preproinsulin

    • C. 

      Preproinsulin is degraded into insulin and then secreted

    • D. 

      Preproinsulin is processed by proinsulin and then by insulin to be secreted

  • 3. 
    What cells in the pancreas release glucagon?
    • A. 

      Pancreatic Alpha cells

    • B. 

      Pancreatic Beta cells

    • C. 

      Hepatic Acrine cells

    • D. 

      Insulin-dependent cells

  • 4. 
    Which of the following statements is true about Glucagon?
    • A. 

      Secreted by acinar cells into the pancreatic duct

    • B. 

      Secreted by Beta cells of the Islets of Langerhan into the pancreatic duct

    • C. 

      Secreted by Islets of Langerhan cells into blood vessels

    • D. 

      Secreted by Alpha cells of the Islets of Langerhan into blood vessels

  • 5. 
    The islets of Langerhans only make up about 1-2% of the total pancreas cells.
    • A. 

      True

    • B. 

      False

  • 6. 
    Insulin is secreted out of the islet of Langerhan cells directly into blood vessels, but glucagon is not.
    • A. 

      True

    • B. 

      False

  • 7. 
    Which of the following statements about the pancreas is true?
    • A. 

      Insulin and glucagon are secreted by the exocrine portion of the pancreas.

    • B. 

      The endocrine pancreas consists of groups of cells known as islets of Langehans whch are embeded in the exocrine portion of the gland.

    • C. 

      The exocrine portion consists of islets of langerhan cells that release hormones such as somatostatin into the pancreatic duct.

    • D. 

      Delta cells of the islets of Langerhans secrete glucagon into blood vessels.

  • 8. 
    Which of the following is not a stimulator of insulin secretion
    • A. 

      Scarcity of food

    • B. 

      Glucose in blood

    • C. 

      Amino acids in blood

    • D. 

      Glucokinase in beta cells

  • 9. 
    Which of the following are stimulators of insulin secretion?
    • A. 

      Secretion from intestine following food intake

    • B. 

      Epinephrine releases during stress, infection or fever

    • C. 

      Amino acids in blood (esp. arginine)

    • D. 

      Glucose in blood

    • E. 

      Scarcity of food

  • 10. 
    Which of the following stimulate the secretion of glucagon by the pancreas?
    • A. 

      High Glucose in blood

    • B. 

      Decrease in plasma glucose

    • C. 

      Increase in epinephrine

    • D. 

      Insulin

    • E. 

      Increase in plasma Amino Acid from a protein -rich meal

    • F. 

      Increase in norepinephrine due to stress, trauma, intense exercise

    • G. 

      Food intake (carbohydrate-rich meal)

  • 11. 
    Look at the image and select the correct order of Insulin synthesis from the options given.
    • A. 

      A, B, C, D, E, F, G

    • B. 

      G, F, E, D, C, B, A

    • C. 

      A, F, D, B, G, C, E

    • D. 

      B, A, D, C, E, F, G

  • 12. 
    To form proinsulin from preproinsulin:
    • A. 

      The signal sequence is cleaved but A & B sequences and C-peptide remain, with disulfide bonds added to join A domain to B domain.

    • B. 

      The C-peptide is cleaved leaving the A and B domains linked via disulfide bonds and the signal sequence.

    • C. 

      The C-peptide and signal sequence remain following the cleavage of the A and B domains

    • D. 

      Only the A and B domains remain bonded via hydrogen bonds to the C- peptide

  • 13. 
    In the formation of insulin, which of the following occurs?
    • A. 

      C-Peptide is cleaved leaving ONLY the A & B disulfide bond linked insulin

    • B. 

      The A and B domains are inverted and joined to the C-Peptide via H-bonds

    • C. 

      The C-Peptide is rejoined to form proinsulin from insulin

    • D. 

      Preproinsulin is cleaved to form insulin with no intermediate form

  • 14. 
    Which of the following pathways are activated by insulin?
    • A. 

      Glucose uptake in muscle and adipose tissue

    • B. 

      Cellular respiration

    • C. 

      Glycogenolysis

    • D. 

      Glycogenesis in liver and muscle

    • E. 

      Protein degradation

    • F. 

      Amino Acid uptake

    • G. 

      Protein Synthesis

  • 15. 
    Which of the following pathways are inhibited by insulin?
    • A. 

      Lipolysis

    • B. 

      Glucose uptake

    • C. 

      Lipoproteins uptake in Adipose tissue

    • D. 

      Protein degradation

    • E. 

      Cellular respiration

    • F. 

      Glycogenolysis

    • G. 

      Protein synthesis

    • H. 

      Protein synthesis

  • 16. 
    Which of the labeled subunits are involved in binding the receptor to the insulin molecule?
    • A. 

      B

    • B. 

      A

  • 17. 
    Which of the following is NOT an intracellular effector involved in insulin function?
    • A. 

      Alpha subunit

    • B. 

      IRS

    • C. 

      Adaptors

    • D. 

      Enzyme effectors

  • 18. 
    Identify the cellular responses to insulin present:
    • A. 

      Increased glucose uptake

    • B. 

      Regulation of transcription

    • C. 

      Activation of enzymes

    • D. 

      Covalent modification and up-regulation

    • E. 

      Decreased glucose uptake

  • 19. 
    In the control of insulin receptor, Autophosphorylation  ____________, while Dephosphorylation _____________.
  • 20. 
    Another way of controlling the insulin receptor is by insulin binding and subsequent dissociation. TRUE OR FALSE?
    • A. 

      True

    • B. 

      False

  • 21. 
    Insulin binding activates tyrosine kinase activity in the intracellular domain of the beta subunit of the insulin receptor.
    • A. 

      True

    • B. 

      False

  • 22. 
    Following insulin binding, tyrosine residues of the beta subunit are dephosphorylated.
    • A. 

      True

    • B. 

      False

  • 23. 
    Receptor tyrosine kinase phosphorylates other proteins, for example, insulin receptor substrates (IRS).
    • A. 

      True

    • B. 

      False

  • 24. 
    After the autophosphorylation of tyrosine and the phosphorylation of intracellular proteins only one signaling pathway is activated by glucose.
    • A. 

      True

    • B. 

      False

  • 25. 
    Biological effects of insulin include all of the following except:
    • A. 

      Increased glucose uptake

    • B. 

      Increaased glycogen synthesis

    • C. 

      Decreased glycogenesis

    • D. 

      Decreased Lypolysis

    • E. 

      Increased fat synthesis

    • F. 

      Increased protein synthesis

    • G. 

      Decreased Glycogenolysis

    • H. 

      Decreased Gluconeogenesis

Back to Top Back to top