Immunology

101 Questions | Attempts: 189
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  • 1/101 Questions

    A larger redness in a wheel and flare reaction means that you are ______

    • More allergic
    • Less allergic
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About This Quiz

Immunology Quiz

Immunology Quizzes & Trivia

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  • 2. 

    The goal of active immunization is the elicitation of protective immunity and immunologic memory

    • True

    • False

    Correct Answer
    A. True
  • 3. 

    ____ is involved in allergenic reactions and is referred to as a reaginic antibody. It laos has a Fc region that binds to receptors on basophils and mast cells. 

    • IgG

    • IgA

    • IgM

    • IgD

    • IgE

    Correct Answer
    A. IgE
  • 4. 

    ____ is found in serum, secreted fluids (sliva tears etc) and is an important component in mucosal immunity

    • IgG

    • IgA

    • IgM

    • IgD

    • IgE

    Correct Answer
    A. IgA
  • 5. 

    ______ is capable of stimulating an immune response

    • Antigen

    • Antibody

    Correct Answer
    A. Antigen
  • 6. 

    A person with persistant, recurrent infections or severe infection by microorganisms that do not usually cause severe infection could potentially have a immunodeficiency disorder

    • True

    • False

    Correct Answer
    A. True
  • 7. 

    Which type of PMN is 60-70% of WBC?

    • Neutrophils

    • Basophils

    • Eosphiophils

    • Macrophage

    Correct Answer
    A. Neutrophils
  • 8. 

    A non-hodgkins lymphoma and kaposis sarcoma are two examples of someone who could potentially have a immunodeficiency disorder

    • True

    • False

    Correct Answer
    A. True
  • 9. 

    50% of patients with SCID lack adenosine deaminase (ADA)

    • True

    • False

    Correct Answer
    A. True
  • 10. 

    Type II hypersensitivity is mediated  by

    • IgE

    • IgM

    • IgA

    • IgG and IgM

    Correct Answer
    A. IgG and IgM
  • 11. 

    Type I hypersensitivity is mediated by

    • IgA

    • IgE

    • IgG

    • IgM

    Correct Answer
    A. IgE
  • 12. 

    IgE binds to high affinity IgE specific FC receptors on basophils and mast cells which are cross linked by allergens

    • True

    • False

    Correct Answer
    A. True
  • 13. 

    Active immunotherapy stimulates an immune response that can directly target tumor antigens

    • True

    • False

    Correct Answer
    A. True
  • 14. 

    Which class of MHC molecules present peptides to CD4+ lymphocytes

    • Class I

    • Class II

    • Class III

    Correct Answer
    A. Class II
  • 15. 

    A bee sting is considered a Type ____ hypersensitivity 

    • I

    • II

    • III

    • IV

    Correct Answer
    A. I
  • 16. 

    Type II hypersensitivities can be drug induced

    • True

    • False

    Correct Answer
    A. True
  • 17. 

    If you wanted to utilizes NK cells to kill a tumor, the tumor would have to lack class I MHC; have a sepcific NIK antibody; or have specific NK adhesion molecules

    • True

    • False

    Correct Answer
    A. True
  • 18. 

    Which class of MHC proteins interacts with the TCRs of CD8+ T lymphocytes

    • MHC Class I

    • MHC Class II

    • MHC Class III

    Correct Answer
    A. MHC Class I
  • 19. 

    T cell receptors are responsible for

    • Recognizing antigens bound to MHC molecules

    • Recognizing antibodies on foreign cells

    • Recognizing B cell antibodies

    • Expressing CD2

    Correct Answer
    A. Recognizing antigens bound to MHC molecules
  • 20. 

    ______ is the corecptor which assists the T cell receptor with an antigen presenting cell

    • CD4

    • CD8

    • CD1

    • CD2

    Correct Answer
    A. CD4
  • 21. 

    ____ is the predominant antibody in secondary immune responses

    • IgG

    • IgA

    • IgM

    • IgD

    • IgE

    Correct Answer
    A. IgG
  • 22. 

    ____ is the first immunoglobulin to appear in phylogeny, the first immunoglobulin to appear in response to antigen stimulation, and is the first antigen to appear in otogeny. 

    • IgG

    • IgA

    • IgM

    • IgD

    • IgE

    Correct Answer
    A. IgM
  • 23. 

    What type of cell is not involved in innate immunity

    • Macrophages

    • Neutrophils

    • Natural Kiler Cells

    • T Lymphocyte

    Correct Answer
    A. T Lymphocyte
  • 24. 

    PAMPs are recognized by

    • Antigens

    • Pattern Recognition Receptor

    • Antibodies

    • Phagocytes

    Correct Answer
    A. Pattern Recognition Receptor
  • 25. 

    Antibodies are inable to penetrate a tumor

    • True

    • False

    Correct Answer
    A. True
  • 26. 

    Natural Killer Cells are proliferated to

    • IL-1

    • IL-2

    • IL-3

    • IL-4

    Correct Answer
    A. IL-2
  • 27. 

    Perforin is ______ dependent

    • Ca++

    • Na+

    • K+

    • Cl-

    Correct Answer
    A. Ca++
  • 28. 

    _____ is the coreceptor which is found on cytotoxic T cells

    • CD1

    • CD2

    • CD4

    • CD8

    Correct Answer
    A. CD8
  • 29. 

    Asthma, insect venom sesnitivity, and atropic dermatitis is an example of what type of hypersensitivity?

    • I

    • II

    • III

    • IV

    Correct Answer
    A. I
  • 30. 

    Which molecule mediates interactions of leukocytes with other leukokocytes or body cells? 

    • MHC

    • Mast Cells

    • Antigens

    • Antibodies

    Correct Answer
    A. MHC
  • 31. 

    A patient with wiskott aldrich symptoms would have excellent blood clotting

    • True

    • False

    Correct Answer
    A. False
  • 32. 

    What T cells activate Macrophages?

    • CD8+ CTL and CD4+ helpers

    • CD4+ CTL and CD8+ helpers

    • CD4- CTL and CD8- helpers

    • CD8- CTL and CD8+ helpers

    Correct Answer
    A. CD8+ CTL and CD4+ helpers
  • 33. 

    If a antibody covers the TSA, will the tumor escape the immune system?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 34. 

    What molecule does IgE use to bind and activate eosinophils?

    • CD4

    • CD18

    • CD23 (FceRII)

    • CD8

    Correct Answer
    A. CD23 (FceRII)
  • 35. 

    An example of a microbial non-self molecule is a 

    • PAMP

    • Neutrophils

    • Eosinophils

    • Heparin

    • FC Receptor

    Correct Answer
    A. PAMP
  • 36. 

    Which PMN stains red in a geimsa stain?

    • Neutrophil

    • Eosinophil

    • Basophil

    • Macrophage

    Correct Answer
    A. Eosinophil
  • 37. 

    A NK cell expresses

    • CD16 (FcgRIII)

    • CD8

    • CD4

    • CD2

    Correct Answer
    A. CD16 (FcgRIII)
  • 38. 

    Autoimmune/drug induced hemolytic anemia, transfusion reactions, rhematic fever are an example of wht type of hypersensitivity?

    • I

    • II (cytotoxic)

    • II (noncytotoxic)

    • III

    • IV

    Correct Answer
    A. II (cytotoxic)
  • 39. 

    The goal of active immunization is transient protection or alleviation of an existing condition

    • True

    • False

    Correct Answer
    A. False
  • 40. 

    Type III hypersensitivity is mediated by

    • IgE

    • Soluble antibodies to moleculeso in cells and tissues

    • Immune complexes from chronic exposure to antigens

    • Immunocytes

    Correct Answer
    A. Immune complexes from chronic exposure to antigens
  • 41. 

    A coombs reagent is 

    • Anti-IgG

    • Anti-IgA

    • Anti-IgM

    • Anti-IgE

    Correct Answer
    A. Anti-IgG
  • 42. 

    What type of receptor found on the surface of certain cells binds to antibodies on invading cells or pathogens?

    • Fc receptors

    • Toll Like Receptor

    • C3a

    • FCeR1

    • IL4 Receptor

    • None of the above

    Correct Answer
    A. Fc receptors
  • 43. 

    What causes a increase in lytic machinery in NK cells after the recruitment and activation of the protein kinase?

    • Production of IFN gamma; Increase in IL-2R

    • Halt production of IFN gamma; Decrease IL-2R

    • Production of IFN beta; Increase in IL-4

    • Production of IFN beta; Increase in IL-4

    Correct Answer
    A. Production of IFN gamma; Increase in IL-2R
  • 44. 

    Which disease is charactarized by creamy white or bluish white patches on the tounge? 

    • Chronic Mucocutaneous candidiasis

    • DiGeorge Syndrome

    • Severe combined deficiencies disease (SCID)

    • X linked infantile aggaglobulinemia

    Correct Answer
    A. Chronic Mucocutaneous candidiasis
  • 45. 

    Give an example of a PMN

    • T lymphocyte

    • Erythrocyte

    • Eosinophil

    • Macrophage

    • Natural Killer Cell

    Correct Answer
    A. Eosinophil
  • 46. 

    Type II Hypersensitivity is mediated by

    • IgE

    • Soluble antibodies to molecules on cells and tissues

    • Immune complexes from chronic exposure to antigens

    • Immunocytes

    Correct Answer
    A. Soluble antibodies to molecules on cells and tissues
  • 47. 

    Which B lymphocyte disorder causes decreased immune function in the mucosal surface in the mouth, GI tract, and lungs resulting in an increased risk for respiratory and GI infections?

    • X-linked infantile aggaglobulinemia

    • Transient hypogammaglobulinemia

    • Common variable hypogammaglobulinemia

    • IgA deficiency

    Correct Answer
    A. IgA deficiency
  • 48. 

    Which type of cell participates ONLY in innate immunity?

    • Macrophage

    • T lymphocyte

    • B lymphocyte

    • Natural Killer Cells

    Correct Answer
    A. Natural Killer Cells
  • 49. 

    Cytotoxic T Lymphocyte mediated destruction of cells are _________ mediated

    • Perforin

    • Na+ / K+

    • CD18

    • CD4

    Correct Answer
    A. Perforin

Quiz Review Timeline (Updated): Sep 23, 2012 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Sep 23, 2012
    Quiz Edited by
    ProProfs Editorial Team
  • Sep 10, 2012
    Quiz Created by
    Rickythegreat
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