Immunology: Tcrs, Cytokines, Immunity Reactions At The Cellular Level
TEST 3 IMMUNOLOGY
- 1.Cytokines involved in acquired immunity
- A.
IL-1, IL-6, IL-18, IFN-A, IFN-B, AND TNF-A
- B.
IL-2, IL-4, IL-5, IL-13, IFN-G, TNF-B, AND TGF-B
- C.
ONLY IL-1, IL-6, IL-12, AND TNF-A
- D.
ONLY IFN-G, AND IL-10
- 2.CHEMOKINES ARE PRODUCED MOSTLY BY WHICH MOLECULES
- A.
NK CELLS
- B.
MACROPHAGES
- C.
ENDOTHELIAL CELLS, EPITHELIAL CELLS, AND FIBROBLASTS
- D.
TH1 AND TH2 CELLS
- 3.WHICH OF THE FOLLOWING MOLECULES ARE MACROPHAGE DEACTIVATING FACTORS BLOCKING MACROPHAGE FUNCTIONS, INCLUDING TNF-A RELEASE:
- A.
E SERIES PROSTAGLANDINS
- B.
TGF-B
- C.
IL-4 AND IL-10
- 4.IL-8 IS WHICH TYPE OF CHEMOKINE
- A.
CC-CC
- B.
CXC
- C.
CXCX
- D.
CXXC
- 5.WHICH OF THE FOLLOWING IS TRUE REGARDING THE NUMBER OF SUBFAMILIES OF CHEMOKINES
- A.
2
- B.
4
- C.
3
- D.
0 SUBFAMILIES
- 6.THE INNATE IMMUNITY CYTOKINES ARE:
- A.
IL-1, IL-6, IL-12 AND TNF-A ONLY
- B.
IL-2, IL-4, IL-5, IL-13, IFN-G, TNF-B, AND TGF-B
- C.
ONLY IFN-G AND IL-2
- D.
IL-1, IL-6, IL-12, IL-18, IFN-A, IFN-B, AND TNF-A
- 7.THE SIGNATURE CYTOKINES PRODUCED BY TH1 CELLS
- A.
IL-10
- B.
IFN-G AND SOMETIMES IL-2
- C.
TNF-A
- 8.WHICH ARE THE SIGNATURE CYTOKINES PRODUCED BY TH2 CELLS
- A.
IL-4
- B.
IL-2
- C.
IL-10
- 9.WHICH INTERLUEKIN IS ALSO LAF?
- 10.TRUE OR FALSE: A T CELL CAN RELEASE ITS RECEPTOR AND RECOGNIZE ANTIGEN IN ITS NATURAL STATE
- A.
FALSE
- B.
TRUE
- 11.WHICH OF THE FOLLOWING ARE ANTIGEN PRESENTING CELLS
- A.
MACROPHAGE
- B.
DENDRITIC CELLS
- C.
B CELLS
- 12.A/B TCRs HAVE A TOTAL DIVERSITY OF:
- A.
~ 1O^18
- B.
~ 10^13
- C.
~ 10^14
- D.
~ 10^15
- 13.COLIGATION OF TCR WITH MHC/PEPTIDE CTLA-4 WITH B7 LEADS TO
- A.
ARREST OF CELL-CYCLE AND TERMINATION OF T-CELL ACTIVATION
- B.
ENABLES T CELL TO BE RECOGIZED BY BOTH CELL-CLL CONTACT AND CYTOKINES
- C.
PROMOTES B-CELL PROLIFERATION AND DIFFERENTIATION, PREVENTS APOPTOSIS OF GERMINAL CENTER B CELLS AND PROMOTES ANTIBODY CLASS SWITCHING
- 14.WHICH INTERACTIONS ARE ESSENTIAL FOR DIALOGUE BETWEN B AND T CELLS?
- A.
CD28-B7
- B.
CD2-CD58
- C.
CD40-CD40L
- 15.FOLLICULAR DENDRITIC CELLS
- A.
HOLD PROCESSED ANTIGEN ON SURFACE IN THE FORM OF SHORT-LIVED IMMUNE COMPLEXES
- B.
HOLD UNPROCESSED, INTACT, ANTIGEN ON THEIR SURFACE INT HE FORM OF SHORT LIVED IMMUNE COMPLEXES
- C.
HOLD INTACT, UNPROCESSED LONG LIVED IMMUNE COMPLEXES ON THEIR SURFACE
- D.
HOLD PROCESSED, INTACT LONG LIVED ANTIGEN IN THE FORM OF LONG LIVED IMMUNE COMPLEXES ON THEIR SURFACE
- 16.THYMUS IS ROUGHLY DIVIDED INTO
- A.
4 REGIONS
- B.
2 REGIONS
- C.
3 REGIONS
- D.
5 REGIONS
- 17.CELLS ENTERING THE CORTICO-MEDULLARY JUNCTION EXPRESS CD3 ON THEIR CELL SURFACE
- A.
True
- B.
False
- 18.WHERE MIGHT ONE FIND CD25+CD44+CD4-CD8-
- A.
REGION 1 OF THE THYMUS
- B.
REGION 2 OF THE THYMUS
- C.
REGION 3 OF THE THYMUS
- D.
REGION 4 THE THYMUS
- 19.WHICH OF THE FOLLOWING CORRESPOND TO THE DN1 PHASE OF T CELL DEVELOPMENT
- A.
UNCOMMITTED PROGENITORS; CD44+CD25-CD4-CD8-
- B.
CLONAL EXPANSION
- C.
LOSE POTENTIAL TO BECOME B CELLS OR NK CELLS
- D.
CELLS COMMIT TO T CELL LINEAGE AND TCR B-CHAIN REARRANGEMENT OCCURS
- 20.DOUBLE POSITIVE CD44-CD25-CD4+CD8+ CELLS ARE FOUND
- A.
IN REGION 1 OF THE THYMUS
- B.
IN REGION 2 OF THE THYMUS
- C.
IN REGION 3 OF THE THYMUS
- D.
IN REGION 4 OF THE THYMUS
- 21.AT WHICH STAGE IS THE T CELL'S FATE DETERMINED
- A.
STAGE 1
- B.
STAGE 2
- C.
STAGE 3
- D.
STAGE 4
- 22.WHICH OF THE FOLLOWING ARE CHARACTERISTICS OF THE DN3 PHASE OR REGION 3 OF T CELL DEVELOPMENT?
- A.
CELLS COMMIT TO T CELL LINEAGE
- B.
TCR B-CHAIN REARRANGEMENT OCCURS
- C.
T CELL LINEAGES ALPHA/BETA OR GAMMA/DELTA DIVERGE
- D.
CD44-CD25+CD4-CD8-
- E.
ALL OF THE ABOVE
- 23.POSITIVE SELECTION OCCURS MAINLY
- A.
IN THE MEDULLA
- B.
IN THE SUBCAPSULAR EPITHELIUM
- C.
IN THE CORTEX
- D.
IN THE CORTICO-MEDULLARY JUNTION
- 24.NEGATIVE SELECTION OCCURS MAINLY
- A.
IN THE CORTEX
- B.
IN THE SUBCAPSULAR EPITHELIUM
- C.
IN THE MEDULLA
- D.
IN THE CORTICO-MEDULLARY JUNCTION
- 25.WHICH CELLS MEDIATE NEGATIVE SELECTION
- A.
THYMIC EPITHELIAL CELLS
- B.
THYMIC DENDRITIC CELLS
- C.
THYMIC MACROPHAGES
- D.
CD3+TCR+ T CELLS
- E.
A, B, AND C
Back to top