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Questions and Answers
  • 1. 

    Which of the following syndromes corresponds to: A failure of neutrophils to generate an immune response and lab values indicate elevated IgE levels? 

    • A.

      Job's syndrome

    • B.

      Wiskott-Aldrich syndrome

    • C.

      Carcinoid syndrome

    • D.

      Mallory-Weiss syndrome

    Correct Answer
    A. Job's syndrome
    Explanation
    Job's syndrome, also known as hyper-IgE syndrome, is characterized by a failure of neutrophils to generate an immune response. This results in recurrent infections and elevated levels of IgE in the lab values. Wiskott-Aldrich syndrome is a primary immunodeficiency disorder characterized by eczema, thrombocytopenia, and recurrent infections. Carcinoid syndrome is a group of symptoms that occur due to the release of certain chemicals by neuroendocrine tumors. Mallory-Weiss syndrome is a condition characterized by bleeding from a tear in the lining of the esophagus or stomach.

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  • 2. 

    Which of the following syndromes corresponds to: right sided valvular disease and diarrhea?

    • A.

      Job's syndrome

    • B.

      Wiskott-Aldrich syndrome

    • C.

      Carcinoid syndrome

    • D.

      Mallory-Weiss syndrome

    Correct Answer
    C. Carcinoid syndrome
    Explanation
    Carcinoid syndrome is the correct answer because it is characterized by the presence of right-sided valvular disease and diarrhea. Carcinoid tumors, which are usually found in the gastrointestinal tract, can release serotonin and other vasoactive substances into the bloodstream. These substances can cause fibrosis and thickening of the heart valves, particularly the tricuspid and pulmonary valves on the right side of the heart. Additionally, the release of serotonin can lead to increased motility of the intestines, resulting in diarrhea.

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  • 3. 

    Which of the following syndromes corresponds to: lab values indicate elevated IgA levels and presence of thrombocytopenia?

    • A.

      Job's syndrome

    • B.

      Wiskott-Aldrich syndrome

    • C.

      Carcinoid syndrome

    • D.

      Mallory-Weiss syndrome

    Correct Answer
    B. Wiskott-Aldrich syndrome
    Explanation
    Wiskott-Aldrich syndrome is a rare X-linked recessive disorder characterized by elevated IgA levels and thrombocytopenia. This syndrome affects the immune system and causes a decrease in the number and size of platelets, leading to increased bleeding and bruising. The elevated IgA levels indicate an abnormal immune response. Job's syndrome, Carcinoid syndrome, and Mallory-Weiss syndrome do not involve elevated IgA levels and thrombocytopenia, making them incorrect choices for this question.

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  • 4. 

    Which of the following syndromes corresponds to: presence of arthritis and commonly found in males?

    • A.

      Reiter's syndrome

    • B.

      Sjogren's syndrome

    • C.

      Kartagener's syndrome

    • D.

      Ehlers-Danlos syndrome

    Correct Answer
    A. Reiter's syndrome
    Explanation
    Reiter's syndrome is the correct answer because it is a syndrome characterized by the presence of arthritis and is commonly found in males. This syndrome typically involves inflammation of the joints, eyes, and urinary tract, and is often associated with a previous infection, such as a sexually transmitted infection or gastrointestinal infection. It predominantly affects males, although females can also be affected.

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  • 5. 

    Which of the following syndromes corresponds to: immotile sperm and presence of reoccurring sinusitis?

    • A.

      Reiter's syndrome

    • B.

      Sjogren's syndrome

    • C.

      Kartagener's syndrome

    • D.

      Ehlers-Danlos syndrome

    Correct Answer
    C. Kartagener's syndrome
    Explanation
    Kartagener's syndrome is characterized by immotile sperm and reoccurring sinusitis. This syndrome is a genetic disorder that affects the cilia, which are responsible for the movement of sperm and the clearance of mucus in the respiratory tract. As a result, individuals with Kartagener's syndrome often have infertility due to immotile sperm and are prone to chronic sinusitis. Reiter's syndrome is associated with arthritis, Sjogren's syndrome involves dry eyes and mouth, and Ehlers-Danlos syndrome affects connective tissues, none of which are related to the symptoms described.

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  • 6. 

    Which of the following syndromes corresponds to: presence of arthritis, xerophthalmia and commonly found in females?

    • A.

      Reiter's syndrome

    • B.

      Sjogren's syndrome

    • C.

      Kartagener's syndrome

    • D.

      Ehlers-Danlos syndrome

    Correct Answer
    B. Sjogren's syndrome
    Explanation
    Sjogren's syndrome is the correct answer because it is characterized by the presence of arthritis and xerophthalmia (dry eyes) which are both mentioned in the question. Additionally, Sjogren's syndrome is commonly found in females, further supporting the answer choice. Reiter's syndrome is not associated with xerophthalmia, Kartagener's syndrome is not associated with arthritis, and Ehlers-Danlos syndrome is not associated with xerophthalmia or commonly found in females.

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  • 7. 

     Which of the following syndromes corresponds to: excessive movement occurring at joints and loose skin?

    • A.

      Reiter's syndrome

    • B.

      Sjogren's syndrome

    • C.

      Kartagener's syndrome

    • D.

      Ehlers-Danlos syndrome

    Correct Answer
    D. Ehlers-Danlos syndrome
    Explanation
    Ehlers-Danlos syndrome is a genetic disorder that affects the connective tissues in the body. It is characterized by excessive movement occurring at joints, which is known as hypermobility, and loose or stretchy skin. This syndrome is caused by a defect in the production of collagen, which is a protein that provides strength and elasticity to the connective tissues. The symptoms can vary widely among individuals, but joint hypermobility and skin laxity are common features of Ehlers-Danlos syndrome.

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  • 8. 

    Which of the following syndromes corresponds to: hematuria, glomerulonephritis and pulmonary dysfunction?

    • A.

      Brown-Sequard syndrome

    • B.

      Thoracic outlet syndrome

    • C.

      Angelman's syndrome

    • D.

      Goodpasture's syndrome

    Correct Answer
    D. Goodpasture's syndrome
    Explanation
    Goodpasture's syndrome is a rare autoimmune disorder characterized by the presence of autoantibodies that attack the basement membrane of the kidneys and lungs. This leads to glomerulonephritis, causing hematuria, and pulmonary dysfunction. The autoantibodies specifically target the alpha-3 chain of type IV collagen, which is found in the basement membrane of these organs. This syndrome can result in kidney failure and respiratory failure if left untreated.

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  • 9. 

    Which of the following syndromes corresponds to: presence of ipsilateral motor loss and contralateral spinothalmic tract damage?

    • A.

      Brown-Sequard syndrome

    • B.

      Thoracic outlet syndrome

    • C.

      Angelman's syndrome

    • D.

      Goodpasture's syndrome

    Correct Answer
    A. Brown-Sequard syndrome
    Explanation
    Brown-Sequard syndrome is characterized by the presence of ipsilateral motor loss and contralateral spinothalamic tract damage. This syndrome occurs due to a hemisection or damage to one side of the spinal cord. The motor loss on the same side as the injury is a result of damage to the corticospinal tract, while the contralateral spinothalamic tract damage leads to loss of pain and temperature sensation on the opposite side of the body. Therefore, Brown-Sequard syndrome is the correct answer for this question.

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  • 10. 

    Which of the following syndromes corresponds to: C8/T1 nerve involvement and weakness in hand muscles?

    • A.

      Brown-Sequard syndrome

    • B.

      Thoracic outlet syndrome

    • C.

      Angelman's syndrome

    • D.

      Goodpasture's syndrome

    Correct Answer
    B. Thoracic outlet syndrome
    Explanation
    Thoracic outlet syndrome is the correct answer because it involves the compression or irritation of the nerves or blood vessels in the thoracic outlet, which is the space between the collarbone and the first rib. This can result in symptoms such as weakness in the hand muscles, pain, and numbness or tingling in the arm or hand. C8/T1 nerve involvement refers to the eighth cervical and first thoracic nerves, which are affected in thoracic outlet syndrome.

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  • 11. 

    Which of the following syndromes corresponds to: maternal genetic phenotype syndrome?

    • A.

      Brown-Sequard syndrome

    • B.

      Thoracic outlet syndrome

    • C.

      Angelman's syndrome

    • D.

      Goodpasture's syndrome

    Correct Answer
    C. Angelman's syndrome
    Explanation
    Angelman's syndrome is a genetic disorder caused by a deletion or mutation of the UBE3A gene inherited from the mother. This syndrome is characterized by developmental delays, intellectual disability, speech impairments, and a happy and excitable personality. Therefore, it corresponds to the "maternal genetic phenotype syndrome" as it is directly related to the genetic makeup of the mother.

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  • 12. 

    Which of the following syndromes corresponds to: Abnormal development of the 3rd and 4th (Pharyngeal pouches)?

    • A.

      Acute coronary syndrome

    • B.

      ARDS

    • C.

      Budd-Chiari syndrome

    • D.

      DiGeorge's syndrome

    Correct Answer
    D. DiGeorge's syndrome
    Explanation
    DiGeorge's syndrome is the correct answer because it is a genetic disorder that is characterized by the abnormal development of the third and fourth pharyngeal pouches. These pouches are responsible for the formation of various structures in the body, including the thymus and parathyroid glands. In DiGeorge's syndrome, there is a defect in the migration and differentiation of the cells derived from these pouches, leading to the underdevelopment or absence of these structures. This can result in a weakened immune system and problems with calcium regulation, among other symptoms.

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  • 13. 

    Which of the following syndromes corresponds to: leads to an increased risk of stroke?

    • A.

      Acute coronary syndrome

    • B.

      ARDS

    • C.

      Budd-Chiari syndrome

    • D.

      DiGeorge's syndrome

    Correct Answer
    A. Acute coronary syndrome
    Explanation
    Acute coronary syndrome refers to a group of conditions that occur due to reduced blood flow to the heart, usually caused by atherosclerosis. This can lead to the formation of blood clots that can block the blood vessels supplying the heart, increasing the risk of a heart attack or stroke. Therefore, Acute coronary syndrome is the correct answer as it is associated with an increased risk of stroke.

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  • 14. 

    Which of the following syndromes corresponds to: abdominal pain, ascites, and hepatic vein occulsions?

    • A.

      Acute coronary syndrome

    • B.

      ARDS

    • C.

      Budd-Chiari syndrome

    • D.

      DiGeorge's syndrome

    Correct Answer
    C. Budd-Chiari syndrome
    Explanation
    Budd-Chiari syndrome is a rare condition characterized by the obstruction of the hepatic veins, which are responsible for draining blood from the liver. This blockage can lead to abdominal pain and ascites, which is the accumulation of fluid in the abdominal cavity. The hepatic vein occlusions mentioned in the question are a key feature of Budd-Chiari syndrome, making it the correct answer. Acute coronary syndrome, ARDS, and DiGeorge's syndrome are unrelated conditions and do not present with the specific symptoms mentioned.

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  • 15. 

    Which of the following syndromes corresponds to: increased pulmonary permeability and fluid entering the lung space?

    • A.

      Acute coronary syndrome

    • B.

      ARDS

    • C.

      Budd-Chiari syndrome

    • D.

      DiGeorge's syndrome

    Correct Answer
    B. ARDS
    Explanation
    ARDS stands for Acute Respiratory Distress Syndrome. It is a condition characterized by increased pulmonary permeability and fluid entering the lung space. This leads to severe respiratory distress and difficulty in breathing. Acute coronary syndrome refers to a group of conditions related to decreased blood flow to the heart, Budd-Chiari syndrome is a liver disorder caused by the obstruction of the hepatic veins, and DiGeorge's syndrome is a genetic disorder affecting multiple organ systems.

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  • 16. 

    Which of the following syndromes corresponds to: can be caused by high doses of Tetracyclines?

    • A.

      Dubin-Johnson syndrome

    • B.

      Fanconi's syndrome

    • C.

      Edward's syndrome

    • D.

      Cri-du-chat syndrome

    Correct Answer
    B. Fanconi's syndrome
    Explanation
    Fanconi's syndrome is a disorder characterized by dysfunction of the kidneys, leading to the impaired reabsorption of certain substances. High doses of Tetracyclines, a group of antibiotics, can cause damage to the renal tubules and result in Fanconi's syndrome. This syndrome is characterized by excessive excretion of glucose, amino acids, phosphate, and bicarbonate in the urine. Therefore, the correct answer is Fanconi's syndrome.

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  • 17. 

     Which of the following syndromes corresponds to: caused by poor liver excretion?

    • A.

      Dubin-Johnson syndrome

    • B.

      Fanconi's syndrome

    • C.

      Edward's syndrome

    • D.

      Cri-du-chat syndrome

    Correct Answer
    A. Dubin-Johnson syndrome
    Explanation
    Dubin-Johnson syndrome corresponds to poor liver excretion. This syndrome is a rare genetic disorder that affects the liver's ability to transport bilirubin, a yellow pigment produced during the breakdown of red blood cells, out of the liver and into the bile. As a result, bilirubin builds up in the liver and spills into the bloodstream, causing a yellow discoloration of the skin and eyes (jaundice). Therefore, Dubin-Johnson syndrome is the correct answer for the given question.

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  • 18. 

    Which of the following syndromes corresponds to: chromosomal deficit of #5?

    • A.

      Dubin-Johnson syndrome

    • B.

      Fanconi's syndrome

    • C.

      Edward's syndrome

    • D.

      Cri-du-chat syndrome

    Correct Answer
    D. Cri-du-chat syndrome
    Explanation
    Cri-du-chat syndrome, also known as 5p- syndrome, is caused by a chromosomal deletion of the short arm of chromosome 5. This syndrome is characterized by a high-pitched cry, intellectual disability, microcephaly, and distinctive facial features. The name "Cri-du-chat" refers to the cat-like cry that affected infants make, resembling the mewing of a distressed kitten. Therefore, the correct answer for the given question is Cri-du-chat syndrome, as it corresponds to a chromosomal deficit of #5.

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  • 19. 

    Which of the following syndromes corresponds to: chromosomal deficit of #18?

    • A.

      Dubin-Johnson syndrome

    • B.

      Fanconi's syndrome

    • C.

      Edward's syndrome

    • D.

      Cri-du-chat syndrome

    Correct Answer
    C. Edward's syndrome
    Explanation
    Edward's syndrome, also known as trisomy 18, is a chromosomal disorder caused by the presence of an extra copy of chromosome 18. This results in various physical and developmental abnormalities. The syndrome is characterized by distinctive facial features, heart defects, organ malformations, and intellectual disabilities. Individuals with Edward's syndrome often have a shortened lifespan and require specialized medical care. Therefore, Edward's syndrome corresponds to a chromosomal deficit of #18.

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  • 20. 

    Which of the following syndromes corresponds to: chromosomal deficit of #13?

    • A.

      Dubin-Johnson syndrome

    • B.

      Patau's syndrome

    • C.

      Edward's syndrome

    • D.

      Down syndrome

    Correct Answer
    B. Patau's syndrome
    Explanation
    Patau's syndrome, also known as trisomy 13, is a chromosomal disorder characterized by the presence of an extra copy of chromosome 13. This chromosomal deficit of #13 leads to a range of physical and intellectual disabilities. Individuals with Patau's syndrome often have multiple congenital abnormalities, including heart defects, cleft lip and palate, and brain malformations. They may also experience developmental delays, intellectual disabilities, and have a shortened lifespan.

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  • Mar 20, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • May 17, 2012
    Quiz Created by
    RNpedia.com
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