Coagulation Study Questions

58 Questions | Total Attempts: 4093

SettingsSettingsSettings
Please wait...
Coagulation Study Questions

MLT study questions


Questions and Answers
  • 1. 
    All of the following conditions cause an increased (prolonged) thrombin time except
    • A. 

      Hypofibrinogenemia

    • B. 

      Increased fibrin-degradation products

    • C. 

      Heparin therapy

    • D. 

      Decreased prothrombin

  • 2. 
    The end product of the interaction between platelets and plasma factors, other than fibrinogen, is
    • A. 

      Prothrombin

    • B. 

      Thrombin

    • C. 

      Fibrin

    • D. 

      Factor II

  • 3. 
    Heparin inhibits the clotting of blood by neutralizing the effect of
    • A. 

      Thrombin

    • B. 

      Calcium ions

    • C. 

      Platelets

    • D. 

      Factor VIII

    • E. 

      Factor X

  • 4. 
    Defibrinated plasma, in order to clot when mixed with tissue thromboplastin and calcium, requires an outside source of?
    • A. 

      Heparin

    • B. 

      Calcium chloride

    • C. 

      Barium sulfate

    • D. 

      Fibrinogen

  • 5. 
    Serum differs from plasma by the loss of
    • A. 

      Factor II

    • B. 

      Factor VII

    • C. 

      Thromboplastin

    • D. 

      Fibrinogen

  • 6. 
    The substance necessary to convert fibrinogen to fibrin is
    • A. 

      Platelets

    • B. 

      Thromboplastin

    • C. 

      Thrombin

    • D. 

      Prothrombin

  • 7. 
    Fibrinogen acted on by thrombin forms:
    • A. 

      Fibrin monomers and peptides

    • B. 

      Fibrin monomer and X, Y & D

    • C. 

      Fibrin polymer and XIII

    • D. 

      Fibrin (stable)

  • 8. 
    The clotting factor dependent on Vitamin K is
    • A. 

      Fibrinogen

    • B. 

      Prothrombin

    • C. 

      Thrombin

    • D. 

      AHG

  • 9. 
    The substance active in splitting fibrin, fibrinogen and fragments is
    • A. 

      Plasminogen

    • B. 

      Plasmin

    • C. 

      Peptides

    • D. 

      Thrombin

  • 10. 
    The intrinsic pathway of the coagulation system begins with the activation of
    • A. 

      Factor II

    • B. 

      Factor I

    • C. 

      Factor XII

    • D. 

      Factor V

    • E. 

      Factor VIII

  • 11. 
    The extrinsic pathway is triggered by
    • A. 

      Membrane lipoproteins (phospholipoproteins)

    • B. 

      Tissue factor

    • C. 

      Ca2+

    • D. 

      Factor VII

    • E. 

      Both a and b

  • 12. 
    The common pathway begins with
    • A. 

      Factor X activation

    • B. 

      Factor II activation

    • C. 

      Factor I activation

    • D. 

      Factor XIII activation

    • E. 

      Factor V activation

  • 13. 
    The final stage of the coagulation pathway involves the conversion of
    • A. 

      Factor I to Ia

    • B. 

      Factor II to IIa

    • C. 

      Factor V to Va

    • D. 

      Factor I to fibrin clot

    • E. 

      Factor IX to IXa

  • 14. 
    Prothrombin is
    • A. 

      A protein formed by the liver in the presence of Vitamin K

    • B. 

      An enzyme that converts fibrinogen into fibrin threads

    • C. 

      The end product of the reaction between fibrinogen and thrombin

    • D. 

      A protein released by platelets during coagulation

  • 15. 
    Aspirin ingestion has the following hemostatic effect in a normal person
    • A. 

      Prolongs the bleeding time

    • B. 

      Prolongs the clotting time

    • C. 

      Inhibits factor VIII

    • D. 

      Creates a circulating anticoagulant effect

    • E. 

      No effect

  • 16. 
    Fibrin monomers polymerize to form
    • A. 

      Fibrinopeptide A

    • B. 

      Fibrinopeptide B

    • C. 

      Fibrin polymer

    • D. 

      Stable fibrin

  • 17. 
    Plasminogen is activated by
    • A. 

      Proteolytic enzymes

    • B. 

      Plasmin

    • C. 

      Fragment X

    • D. 

      Fragment Y

  • 18. 
    Activated Protein C acts by
    • A. 

      Precipitating calcium

    • B. 

      Binding calcium

    • C. 

      Activating plasmin

    • D. 

      Inactivating VIIIa

  • 19. 
    Prothrombin is converted to thrombin by
    • A. 

      A complex of activated factors IX and VII and calcium ions

    • B. 

      Calcium ions only

    • C. 

      A complex of phospholipids, factor VII, and calcium ions

    • D. 

      A complex of activated factors X and V, platelet factor 3 and calcium

    • E. 

      None of the above

  • 20. 
    Platelet aggregation is accmplished by the release of
    • A. 

      Proteolytic enzymes

    • B. 

      Phospholipids

    • C. 

      Adenosine diphosphate

    • D. 

      Serotonin

  • 21. 
    Heparin is released from
    • A. 

      Damaged rbcs

    • B. 

      Lymph

    • C. 

      Eosinophils

    • D. 

      Mast cells

  • 22. 
    Circulating anticoagulants are
    • A. 

      Inhibitors

    • B. 

      Inactivators

    • C. 

      Natural occurring

    • D. 

      All of the above

  • 23. 
    Which of the following is a source of error that can affect most coagulation procedures?
    • A. 

      Improper specimen storage

    • B. 

      Improperly reconstituting and storing test reagents

    • C. 

      Improper temperature of reaction

    • D. 

      Improper timing of a test

    • E. 

      All of the above

  • 24. 
    In specimen collection, leaving a tourniquet on too long immediately prior to doing a venipuncture can result in:
    • A. 

      Hemoconcentration

    • B. 

      In vivo clotting

    • C. 

      The vein collapsing

    • D. 

      A hematoma

  • 25. 
    The proper proportion (in parts) of blood to anticoagulant in the PTT and Protime is
    • A. 

      2:1

    • B. 

      3:1

    • C. 

      5:1

    • D. 

      9:1

Back to Top Back to top