Bms 300 Final Review Quiz

73 Questions | Total Attempts: 157

SettingsSettingsSettings
Please wait...
Bms 300 Final Review Quiz

Questions and Answers
  • 1. 
    Signaling of GnRH to gonadotropes is an example of which of the following:
    • A. 

      Autocrine signaling

    • B. 

      Paracrine signaling

    • C. 

      Neutral signaling

    • D. 

      Endocrine signaling

    • E. 

      Neuroendocrine signaling

  • 2. 
    Which of the following is not released by cells in the anterior pituitary?
    • A. 

      Luteinizing hormone (LH)

    • B. 

      Thyroid stimulating hormone (TSH)

    • C. 

      Oxytocin (OT)

    • D. 

      Growth hormone (GH)

    • E. 

      All of the above are released by cells in the anterior pituitary

  • 3. 
    Intracellular receptors require which of the following domains?
    • A. 

      Transactivation domain, DNA binding domain, hormone binding domain

    • B. 

      Translation domain, DNA binding domain, hormone binding domain

    • C. 

      Transactivation domain, mitochondrial binding domain, hormone binding domain

    • D. 

      Transactivation domain, DNA binding domain, mitochondrial binding domain

    • E. 

      Membrane binding domain, translation domain, nuclear binding domain

  • 4. 
    The insulin receptor is a type of cell surface receptor that is activated by phosphorylation after ligand binding. Specifically, the amino acid that is activated by a ______ is _______.
    • A. 

      Kinase; tyrosine

    • B. 

      Phosphatase; tyrosine

    • C. 

      Kinase; insulin

    • D. 

      Phosphatase; insulin

    • E. 

      None of the above

  • 5. 
    Which of the following combinations or statements is INCORRECT?
    • A. 

      GnRH binds cell surface receptors on gonadotropes for release of gonadotropins, which bind cell surface receptors on the gonads

    • B. 

      Estradiol binds primarily to cell surface receptors

    • C. 

      Transcription of protein hormones occurs in the nucleus

    • D. 

      The Pre-prohormone sequence for GnRH is necessary for "signaling" or "localization" information to direct transport

    • E. 

      Intracellular receptors bind small, lipid soluble hormones and can be found in the cytoplasm or nucleus of a cell

  • 6. 
    Which of the following hormones is incorrectly paired with its site of action?
    • A. 

      LH: ovaries, testes

    • B. 

      Parathyroid hormone: bone

    • C. 

      Aldosterone: kidney

    • D. 

      Anti-diurectic hormone (ADH/vasopressin):kidney

    • E. 

      Adrenocorticotropic hormone (ACTH): adrenal medulla

  • 7. 
    Which of the following is NOT a second messenger used as a method of signal amplification for the cell surface receptors with 7 transmembrane domains, termed G-protein coupled receptors (GPCRs)?
    • A. 

      Cyclic AMP (cAMP)

    • B. 

      Diaclgylcerol (DAG)

    • C. 

      Calcium (Ca2+)

    • D. 

      Inositol trisphosphate (IP3)

    • E. 

      All of the above are 2nd messengers

  • 8. 
    Which of the following hormones signal through cell surface receptors? Pick the most appropriate combination of hormones.
    • A. 

      All GI hormones, pancreatic hormones, hypothalamic releasing hormones, and testosterone

    • B. 

      Calcitonin, Parathyroid hormone (PTH), and ALL GI hormones, pancreatic hormones, and hypothalamic releasing hormones

    • C. 

      Estrogen, Calcitonin, Parathyroid hormone (PTH), and ALL GI hormones

    • D. 

      ALL GI hormones, pancreatic hormones, hypothalamic releasing hormones, and phospholipase

    • E. 

      NONE of the above

  • 9. 
    Which of the following statements regarding steroid hormones is TRUE?
    • A. 

      All steroid hormones are derived from cholesterol, a 25 carbon structure

    • B. 

      ALL steroid hormones undergo side chain cleavage in the Golgi apparatus

    • C. 

      Enzymatic modification of pregnenalone in each tissue is the rate limiting step of steroid production

    • D. 

      Pregnenalone is the 27 carbon intermediary produced by lateral chain cleavage

    • E. 

      ALL of the above statements are FALSE

  • 10. 
    Which of the following statements regarding amino acid derived hormones is TRUE?
    • A. 

      Epinephrine is closely related to Thryoxin (T4) as they are both derived from a Tryptophane amino acid.

    • B. 

      Epinephrine, a catecholamine, is made in the adrenal cortex.

    • C. 

      Iodination of and modification of tyrosine occurs in the thyroid gland for production of T3 and T4

    • D. 

      T3 is produced in the Parathyroid gland and the oaddition of the last iodine occurs in the thyroid gland to produce T4

    • E. 

      ALL of the above statements are FALSE

  • 11. 
    RNA polymerase functions as part of _____ to produce ______.
    • A. 

      Translation, protein

    • B. 

      Replication, DNA

    • C. 

      Transcription, RNA

    • D. 

      Translation, RNA

    • E. 

      Transcription, protein

  • 12. 
    In the anterior pituitary, hormones are translated (in) on:
    • A. 

      The nucleus

    • B. 

      The Golgi apparatus

    • C. 

      Smooth endoplasmic reticulum

    • D. 

      Rough endoplasmic reticulum

    • E. 

      Free ribosomes

  • 13. 
    Transcription factors bind to _______ to promote _______:
    • A. 

      DNA, DNA synthesis

    • B. 

      RNA, RNA synthesis

    • C. 

      RNA, protein synthesis

    • D. 

      DNA, transcription

    • E. 

      Protein, DNA replication

  • 14. 
    Following a bad cut in the skin, a scar will often form. A scar is formed by connective tissue cells, which in this case are likely ______ from the _______.
    • A. 

      Epithelial cells, stratum corneum

    • B. 

      Chondrocytes, dermis

    • C. 

      Fibrocytes, dermis

    • D. 

      Epithelial cells, stratum basale

    • E. 

      Fibrocytes, stratum basale

  • 15. 
    Two solutions are separated by a membrane that contains only channels permeable to water (aquaporins). The solution in the left-hand compartment contains 50 millimolar NaCl, which dissociates completely, and the right hand compartment contains 100 millimolar urea which is a small, charged molecule that does not dissociate. Which of the following statements is correct?
    • A. 

      Water will not flow because osmotic forces are balanced

    • B. 

      Water will flow from right to left because the osmotic concentration of the NaCl is higher

    • C. 

      Water will flow from left to right because the osmotic concentration of the urea is higher

    • D. 

      Urea will diffuse from right to left

    • E. 

      A and d are correct

  • 16. 
    During the synthesis of kinesin, _____ catalyzes the formation of _____.
    • A. 

      Messenger RNA, peptide bonds

    • B. 

      Transfer RNA, ionic bonds

    • C. 

      Ribosomal RNA, peptide bonds

    • D. 

      Transfer RNA, peptide bonds

    • E. 

      Ribosomal RNA, hydrogen bonds

  • 17. 
    Kinesin is a(n) ________ that moves _______ along ______.
    • A. 

      Kinase, vesicles, microtubles

    • B. 

      ATPase, microtubules, actin

    • C. 

      Kinase, vesicles, actin

    • D. 

      ATPase, vesicles, actin

    • E. 

      ATPase, vesicles, microtubules

  • 18. 
    Keratin, which is found in keratinocytes is a(n):
    • A. 

      Actin complex

    • B. 

      Motor protein

    • C. 

      ATPase

    • D. 

      Intermediate filament protein

    • E. 

      Microtubule binding protein

  • 19. 
    Which of the following proteins would be expected to contain a signal peptide?
    • A. 

      A.) actin

    • B. 

      B.) tubulin

    • C. 

      C.) lysosomal proteins

    • D. 

      D.) a calcium channel

    • E. 

      C and d are correct

  • 20. 
    In comparison to eukaryotes, prokaryotes lack:
    • A. 

      Endoplasmic reticulum

    • B. 

      Ribosomes

    • C. 

      DNA

    • D. 

      RNA

    • E. 

      Protein

  • 21. 
    The signal peptide that emerges from the large ribosomal subunit:
    • A. 

      Is composed of hydrophobic amino acids

    • B. 

      Determines that the protein will be synthesized on rough endoplasmic reticulum

    • C. 

      Binds to a signal recognition particle

    • D. 

      Binds to the protein translocator in the endoplasmic reticulum

    • E. 

      All of the above are correct

  • 22. 
    The ______ comprise the hydrophilic region of biological membranes.
    • A. 

      Phosphate head groups

    • B. 

      Fatty acid side chains

    • C. 

      Carbon to carbon bonds

    • D. 

      Glycerol backbone

    • E. 

      Ester bonds

  • 23. 
    If a tumor is classified as a carcinoma, you can conclude that the tumor originated as a _______ cell.
    • A. 

      Osteocyte

    • B. 

      Epithelial cell

    • C. 

      Chrondrocyte

    • D. 

      Fibrocyte

    • E. 

      A cell in the dermis

  • 24. 
    The role of histones is to:
    • A. 

      Bind to DNA and assist in folding DNA into a chromosome.

    • B. 

      Permit mRNA molecules to fold properly after they are transcribed

    • C. 

      Permit proteins to fold properly in endoplasmic reticulum

    • D. 

      Bind to specific amino acids in the signal sequence

    • E. 

      Escort mRNA molecules through nuclear pores

  • 25. 
    Integrins are examples of ________ proteins that connect epithelial cells to ______ in ______.
    • A. 

      Cytoplasmic, keratin filaments, desmosomes

    • B. 

      Transmembrane, one another, desmonsomes

    • C. 

      Extracellular proteins, the basal lamina, hemidesmosomes

    • D. 

      Transmembrane proteins, basal lamina

    • E. 

      Cytoplasmic proteins, basal lamina, hemidesmosomes

Back to Top Back to top