Think you have good knowledge about antifungal drugs? If yes, then you should take up this 'Antifungal Drug MCQ quiz' to see how much you know about these drugs. A person is more likely to get a fungal infection if they have a weakened immune system or take antibiotics. Antifungal medicines work by either killing the fungal cells or by affecting a substance in the cell walls. So, take this quiz and see how well you can score.
Ampicillin and erythromycin
Saquinavir and foscarnet
Pyrimethamine and sulfadiazine
Amphotericin B and flucytosine
Tolnaftate and nystatin
Terbinafine and griseofulvin
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Inhibition of conversion of squalene to lanosterol
Formation of artificial pores in the fungal membrane
Inhibition of fungal mitosis
Inhibition of squalene synthesis
Inhibition of conversion of lanosterol to ergosterol
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Amphotericin B
Fluconazole
Griseofulvin
Flucytosine
Cyclosporine
Tobramycin
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Fluorouracil
Cytarabine
Flucytosine
Griseofulvin
Ketoconazole
Terbinafine
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Actinomycosis
Brucellosis
Toxoplasmosis
Onychomycosis
Histoplasmosis
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Amphotericin B
Nystatin
Ketoconazole
Flucytosine
Griseofulvin
Terbinafine
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Acyclovir
Metronidazole
Griseofulvin
Vancomycin
Amphotericin B
Flucytosine
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Mebendazole
Metronidazole
Miconazole
Zidovudine
Griseofulvin
Saquinavir
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Flucytosine
Terbinafine
Griseofulvin
Amphotericin B
Nystatin
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Stratum basale
Stratum spinosum
Stratum corneum
Pigment layer
Hair follicle
Hair shaft
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Flucytosine
Penicillin G
Gancyclovir
Amphotericin B
Gentamicin
Zidovudine
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Amphotericin B
Fluconazole
Piperacillin
Metronidazole
Griseofulvin
Nystatin
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Coccidioidomycosis
Histoplasmosis
Aspergillosis
Cryptococcosis
Mucormycosis
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Progressive disseminate histoplasmosis - amphotericin B
Progressive disseminate coccidioidomycosis - fluconazole
Pulmonary blastomycosis - fluconazole
Meningeal cryptococcosis- amphotericin B
Disseminate sporotrichosis - amphotericin B
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Amphotericin B - inhibits thymidylate synthetase
Griseofulvin - interferes with microtubule function
Flucytosine - inhibits fungal mycolic acid synthesis
Miconazole - inhibits DNA dependent RNA polymerase
Nystatin - inhibits ergosterol synthesis
Terbinafine - inhibits squalene epoxidase
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Coccidioides immitis
Mycoplasma pneumoniae
Histoplasma capsulatum
Aspergillus fumigatus
Cryptococcus neoformans
Chlamydia psittaci
Nocardia asteroides
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Metabolic alkalosis is frequent and may be pronounced
A shock-like fall in blood pressure may occur during IV infusion
A sudden decrease of body temperature may occur during IV infusion
Renal toxicity is common, is dose-dependent and may be severe
Amphotericin B toxicity seems to be lower with the use of lipid formulations the drug
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Candida albicans
Malassezia furfur
Trichophyton rubrum
Epidermophyton floccosum
Microsporum gypseum
Pseudomonas aeruginosa
Histoplasma capsulatum
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Amphotericin B - normocytic anemia
Griseofulvin - photosensitivity
Flucytosine - myelosuppression
Ketoconazole - menstrual irregularities
Nystatin - mental confusion
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