Pharm Antihypertensives
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Presenting with hypertension – also known as high blood pressure – can be a rather harrowing realisation for any patient. That said, it isn’t the end of the road. Antihypertensives are drugs used to treat just that very condition, and today we’ll be asking you a number of questions regarding them.
- 1.Directions: questions 1-5 Match each antihypertensive drug with its appropriate mechanism of action (each lettered option can be selected once, more than once, or not at all): Nitric oxide is the active metabolite
- A.
Aliskiren
- B.
Clonidine
- C.
Diazoxide
- D.
Enalapril
- E.
Fenoldopam
- F.
Furosemide
- G.
Hydralazine
- H.
Hydrochlorothiazide
- I.
Labetalol
- J.
Losartan
- K.
Methyldopa
- L.
Nifedipine
- M.
Nitroprusside
- N.
Prazosin
- O.
PropranoloL
- P.
Spironolactone
- Q.
Verapamil
- 2.Directions: questions 1-5 Match each antihypertensive drug with its appropriate mechanism of action (each lettered option can be selected once, more than once, or not at all): Activation of D1 receptors
- A.
Aliskiren
- B.
Clonidine
- C.
Diazoxide
- D.
Enalapril
- E.
Fenoldopam
- F.
Furosemide
- G.
Hydralazine
- H.
Hydrochlorothiazide
- I.
Labetalol
- J.
Losartan
- K.
Methyldopa
- L.
Nifedipine
- M.
Nitroprusside
- N.
Prazosin
- O.
PropranoloL
- P.
Spironolactone
- Q.
Verapamil
- 3.Directions: questions 1-5 Match each antihypertensive drug with its appropriate mechanism of action (each lettered option can be selected once, more than once, or not at all): Blockade of AT1 receptors
- A.
Aliskiren
- B.
Clonidine
- C.
Diazoxide
- D.
Enalapril
- E.
Fenoldopam
- F.
Furosemide
- G.
Hydralazine
- H.
Hydrochlorothiazide
- I.
Labetalol
- J.
Losartan
- K.
Methyldopa
- L.
Nifedipine
- M.
Nitroprusside
- N.
Prazosin
- O.
PropranoloL
- P.
Spironolactone
- Q.
Verapamil
- 4.Directions: questions 1-5 Match each antihypertensive drug with its appropriate mechanism of action (each lettered option can be selected once, more than once, or not at all): Potassium channel opening in smooth muscle cells
- A.
Aliskiren
- B.
Clonidine
- C.
Diazoxide
- D.
Enalapril
- E.
Fenoldopam
- F.
Furosemide
- G.
Hydralazine
- H.
Hydrochlorothiazide
- I.
Labetalol
- J.
Losartan
- K.
Methyldopa
- L.
Nifedipine
- M.
Nitroprusside
- N.
Prazosin
- O.
PropranoloL
- P.
Spironolactone
- Q.
Verapamil
- 5.Directions: questions 1-5 Match each antihypertensive drug with its appropriate mechanism of action (each lettered option can be selected once, more than once, or not at all): Competitive inhibition of renin
- A.
Aliskiren
- B.
Clonidine
- C.
Diazoxide
- D.
Enalapril
- E.
Fenoldopam
- F.
Furosemide
- G.
Hydralazine
- H.
Hydrochlorothiazide
- I.
Labetalol
- J.
Losartan
- K.
Methyldopa
- L.
Nifedipine
- M.
Nitroprusside
- N.
Prazosin
- O.
PropranoloL
- P.
Spironolactone
- Q.
Verapamil
- 6.
- A.
Remarkable postural hypotension
- B.
Decreased cardiac output
- C.
Decreased peripheral vascular resistance
- D.
Increased interstitial fluid volume
- E.
Decreased renal blood flow
- 7.
- A.
Captopril
- B.
Hydrochlorothiazide
- C.
Methyldopa
- D.
Furosemide
- E.
Prazosin
- F.
Minoxidil
- 8.A 65 year-old woman was found to have a blood pressure of 165/90 during a routine visit. Past history of the patient was significant for a second-degree heart block and for osteoporosis. One year ago she had suffered from a severe episode of angioedema. Which of the following antihypertensive drugs would be most appropriate for this patient?
- A.
Captopril
- B.
Propranolol
- C.
Verapamil
- D.
Hydrochlorothiazide
- E.
Minoxidil
- 9.A 52-y/o woman suffering from HTN still had a blood pressure of 156/92 mm Hg after three months of therapy with hydrochlorotiazide and losartan. Her physician decided to add a third drug which acts by decreasing central sympathetic outflow. Which of the following adverse effects might most likely occur after few days of therapy with the new drug?
- A.
Severe postural hypotension
- B.
Megaloblastic anemia
- C.
Palpitations
- D.
Pronounced sedation
- E.
Sialorrhea
- 10.
- A.
Captopril
- B.
Minoxidil
- C.
Nifedipine
- D.
Hydralazine
- E.
Clonidine
- F.
Fenoldopam
- 11.
- A.
Captopril
- B.
Propranolol
- C.
Nifedipine
- D.
Methyldopa
- E.
Prazosin
- F.
Losartan
- 12.A 47-year-old man with a history of hypertension had been taking hydrochlorothiazide for one month, but his blood pressure was not controlled despite adherence to medication and nonpharmacologic measures. The patient was also trying to quit smoking without success. The physician decided to add to the therapeutic regimen a second drug that also could help the patient as an adjunct to a smoking cessation program. Which of the following drug was most likely prescribed?
- A.
Minoxidil
- B.
Propranolol
- C.
Nifedipine
- D.
Clonidine
- E.
Hydralazine
- 13.
- A.
Propranolol
- B.
Minoxidil
- C.
Hydralazine
- D.
Prazosin
- E.
Methyldopa
- F.
Fenoldopam
- 14.A 61-year-old man suffering from hypertension had been taking hydrochlorothiazide and propranolol for two months but the therapy failed to completely control his blood pressure. The man was recently diagnosed with benign prostatic hyperplasia and experienced frequent nocturia. His physician decided to add a third drug which could also help the patient’s difficulty in urinating. A drug from which of the following drug classes was most likely prescribed?
- A.
Alpha-1 blockers
- B.
Ca channel blockers
- C.
Ace inhibitors
- D.
Dopamine D1 blockers
- E.
Alpha-2 agonists
- F.
Beta-blockers
- 15.
- A.
Propranolol
- B.
Clonidine
- C.
Captopril
- D.
Hydrochlorothiazide
- E.
Labetalol
- 16.
- A.
Minoxidil
- B.
Hydralazine
- C.
Clonidine
- D.
Prazosin
- E.
Propranolol
- F.
Captopril
- 17.
- A.
Labetalol and prazosin
- B.
Diazoxide and hydralazine
- C.
Clonidine and captopril
- D.
Nitroprusside and esmolol
- E.
Minoxidil and nifedipine
- 18.
![A 56-year-old woman recently diagnosed with hypertension and atrial fibrillation
started a treatment with atenolol, two tablets daily. Which of the following sets of
physiologic changes was most likely after the administration of the drug?
- ProProfs]( "A 56-year-old woman recently diagnosed with hypertension and atrial fibrillation
started a treatment with atenolol, two tablets daily. Which of the following sets of
physiologic changes was most likely after the administration of the drug?")
A 56-year-old woman recently diagnosed with hypertension and atrial fibrillation started a treatment with atenolol, two tablets daily. Which of the following sets of physiologic changes was most likely after the administration of the drug?- A.
A
- B.
B
- C.
C
- D.
D
- E.
E
- 19.A 56-year-old man complained to his physician of palpitations, sweating and flushing of two day duration. The man, who had been suffering from hypertension for 3 months, had started a therapy with hydrochlorothiazide and captopril but one month later his blood pressure was still 170/100 mm Hg. One week ago the physician decided to add a third antihypertensive agent to the treatment. Which of the following drugs was most likely added to the patient’s therapy?
- A.
Hydralazine
- B.
Propranolol
- C.
Verapamil
- D.
Clonidine
- E.
Nitroprusside
- 20.A 61-year-old man, suffering from stage 2 hypertension for many years, had minoxidil added recently to his antihypertensive therapy. Which of the following actions best explains the antihypertensive effect of this drug?
- A.
Decreased cardiac output
- B.
Decreased central adrenergic tone
- C.
Decreased extracellular fluid volume
- D.
Decreased synthesis of angiotensin II
- E.
Decreased total peripheral resistance
.JPG "A 56-year-old woman recently diagnosed with hypertension and atrial fibrillation
started a treatment with atenolol, two tablets daily. Which of the following sets of
physiologic changes was most likely after the administration of the drug?")
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