Test: Quiz On Diseases! MCQ

19 Questions | Total Attempts: 145

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Test: Quiz On Diseases! MCQ

How much do you know about diseases? Diseases are commonly understood to be medical conditions that encompass a pathological process associated with a specific set of symptoms. Some of the most common classifications of diseases include autoimmune, bacterial, blood, cancer, digestive, heart, nerve sexually transmitted disease, or thyroid. There could be a plethora of unpleasant symptoms you will encounter when you have a disease. This quiz will cure you of your uncertainty, and you will pass the test.


Questions and Answers
  • 1. 
    A 40-year-old man lived in Central America for a year. Five months into his stay, he experienced a bout of dysentery for which he took some antibiotics. A month later, he noticed fever, tiredness, and pain in the right upper quadrant. A liver scan showed an abscess that was associated with elevated blood levels of liver enzymes. How did this disease develop?
    • A. 

      Motile trophozoites from the colon invaded the liver

    • B. 

      Parasitic cysts from the small intestine invaded the liver

    • C. 

      Parasitic eggs traveled in intestinal veins to the liver

    • D. 

      Bacteria from ulcers in the colon migrated to the liver

    • E. 

      A hepatitis virus infected the liver to cause an abscess

  • 2. 
    You are the principal investigator in an HIV-1 prevalence study. In the course of the study in a high-risk group, a week’s worth of sera is screened in the laboratory by ELISA. Serum samples yielding a positive result are then re-tested by western blot analysis for confirmation. The following results are obtained: Which samples are indicative of HIV-1 infection?
    • A. 

      I, II, IV, and V

    • B. 

      II, IV, and V

    • C. 

      I, II, III, IV, and V

    • D. 

      I, II, III, and V

    • E. 

      V

  • 3. 
    A 39-year-old jaundiced man with icteric sclerae has a slightly elevated total serum bilirubin (85% indirect), increased urinary hemoglobin, and hemosiderin. Which of the following is the most likely diagnosis?
    • A. 

      Extravascular hemolysis

    • B. 

      Intravascular hemolysis

    • C. 

      Sickle Cell Anemia

    • D. 

      Acute Internal Blood Loss Anemia

    • E. 

      Chronic Blood Loss Anemia

  • 4. 
    A 16-year-old jaundiced girl is scheduled for splenectomy because of splenomegaly and anemia. Her peripheral blood smear shows a normochromic normocytic anemia of PBS. Her Direct Coombs' test is negative, and osmotic fragility of the red cells is increased. What type of RBCs would most likely be seen of PBS?
    • A. 

      Ovalocytes

    • B. 

      Spherocytes

    • C. 

      Shistocytes

    • D. 

      Depranocytes

    • E. 

      Dacrocytes

  • 5. 
    An autopsy findings from a 65-year-old man revealed a left and right ventricular hypertrophy, nutmeg liver, pulmonary & pedal edema. Which of the following is the most likely cause of death?
    • A. 

      Hypertension

    • B. 

      Myocardial Infarction

    • C. 

      Congestive Heart Failure

    • D. 

      Pulmonary Infarction

    • E. 

      Bowel Infarction

  • 6. 
    A patient is given a mismatch ABO transfusion because of a clerical error. The patient complains of kidney pain and hematuria. Which of the following types of hypersensitivity reaction is most likely?
    • A. 

      Type I

    • B. 

      Type II

    • C. 

      Type III

    • D. 

      Type IV

    • E. 

      Type V

  • 7. 
    You are asked to review lab results shown below. Which of the following antibodies would be most helpful in confirming your diagnosis?
    • A. 

      Antibodies against RNA

    • B. 

      Antibodies against centromeres

    • C. 

      Antibodies against nuclei

    • D. 

      Antibodies against histones

    • E. 

      Antibodies against ds-DNA

  • 8. 
    A 56-year-old Caucasian farmer presented with an ulcerated, erythematous lesion on the dorsum of his right and enlarged ipsilateral axillary lymph nodes. The lesion was biopsied. The gross and microscopic appearance of the mass is shown for your evaluation. Which of the following is the most likely underlying molecular mechanism of the described neoplasm?
    • A. 

      Double-strand DNA break

    • B. 

      Translocation with gene overexpression

    • C. 

      Formation of pyrimidine dimers

    • D. 

      Gene amplification

    • E. 

      Promoter hypermethylation

  • 9. 
    A 44-year-old Indian American female visits her family physician for routine check up. During vaginal examination the physician finds the uterine cervix abnormalities shown for your evaluation. A subsequent cervical biopsy detects a single group of several evidently malignant cells that spreads into the dermis through the basement membrane. Which of the following is the most likely prognosis?
    • A. 

      Metaplasia

    • B. 

      Dysplasia

    • C. 

      Carcinoma in situ

    • D. 

      Microinvasive carcinoma

    • E. 

      Invasive carcinoma

  • 10. 
    A 38-year-old HIV-positive African American female has CD4+ count of 90/microliter. Which of the following is the LEAST likely tumor that can arise in this woman?
    • A. 

      Kaposi sarcoma

    • B. 

      Breast carcinoma

    • C. 

      Uterine cervix carcinoma

    • D. 

      B-cell lymphoma

  • 11. 
    A 51-year-old Caucasian male presents with soft tissue sarcomas, breast cancer, brain tumor, and adrenal cortex tumors. Which of the following carcinogenic mechanisms is most likely implicated in the development of the patient’s disease?
    • A. 

      LOH of p53 gene

    • B. 

      Hypermetylation of promoter of p16 gene

    • C. 

      Loss of DNA excision repair genes

    • D. 

      Loss of homologous recombination repair genes

    • E. 

      LOH of RB gene

  • 12. 
    A 37-year-old African American male, a jazz singer presents with hoarseness of voice. He reports a 25-pack-year history of smoking. Laryngoscopy reveals an area of papillomatous growth (shown) and biopsy is taken. Histological examination of the biopsy reveals fibro-capillary stalks covered by proliferating squamous epithelium with preserved polarity and mild cellular atypia; neither mitotic figures nor penetration through the basement membrane are seen. Which of the following is the most likely diagnosis?
    • A. 

      Squamous cell papilloma

    • B. 

      Chronic laryngitis

    • C. 

      Laryngeal edema

    • D. 

      Fibromyoma

    • E. 

      Squamous cell carcinoma

  • 13. 
    An 18-month old with a history of recurrent bacterial and viral infections, failure to thrive, developmental delay, and tremors is submitted to your care. On exam you notice a lack of peripheral lymphoid tissue. Blood analysis reveals lymphopenia with normal B cell count and normal immunoglobulin levels. Patient is most likely suffering from which of the following?
    • A. 

      Hypoxanthine guanine phosphoribosyl transferase (HGPRT)

    • B. 

      Adenine phosphoribosyl transferase (APRT)

    • C. 

      Purine nucleoside phosphorylase

    • D. 

      Adenosine desaminase (ADA)

    • E. 

      Adenosine kinase

  • 14. 
    You are a neonatologist working in a tertiary care hospital in a state capital. A 4-week old male is transferred to you with severe jaundice that appeared at birth and has been worsening ever since. The boy is the first child of a healthy Jewish couple; pregnancy and vaginal delivery were unremarkable. The boy is of average height and weight for his age, in no acute distress, but shows marked jaundice and slight hepatomegaly. Lab: CBC normal, indirect bilirubin high, low fecal urobilinogen. What is the most likely diagnosis?
    • A. 

      Uridyl glucuronyl transferase deficiency

    • B. 

      Neonatal jaundice

    • C. 

      Dubin-Johnson syndrome

    • D. 

      Rotor (-Manahan-Florentin) syndrome

    • E. 

      Glucose-6-phosphate dehydrogenase deficiency

  • 15. 
    A physician suspected, and the supporting lab results indicated, that his patient’s diagnosis was diffuse intrinsic brain stem glioma. The patient’s prognosis was extremely poor. The doctor needed to present his findings to the patient. The most appropriate delivery of the news to the patient is in keeping with which of the following accurate statements?
    • A. 

      Physicians provide patients with a specific amount of time which patients with their condition are expected to live.

    • B. 

      Physicians provide the patients and families with an optimistic estimate of the amount of time remaining.

    • C. 

      Patients are informed that help with their issues, and support throughout their illness, will become the responsibility of the successive specialists which will be providing their treatment.

    • D. 

      Physicians clarify what can be realistically expected and distinguish this from what might be wished for, or what is most feared.

    • E. 

      Physicians honor a family’s request and withhold patient information if the family assesses a risk for the patient from hearing the bad news.

  • 16. 
    At his most recent routine checkup, a 34-year-old man infected with HIV-1 displays a decrease in his CD4 count and an increase in his viral load. The patient has been on a HAART regimen for the past year that includes the drug maraviroc. Molecular diagnostics reveal that the patient’s viral strain is now displaying significant resistance to maraviroc. Which of the following most likely identifies the mechanism behind this development of viral resistance?
    • A. 

      Shift to a CCR5-CXCR4 dual-tropism

    • B. 

      Mutations in the active site of HIV reverse transcriptase

    • C. 

      Mutations in an allosteric site of HIV reverse transcriptase

    • D. 

      Mutations in the viral gp41 glycoprotein subunit

    • E. 

      Shift to a CCR5-tropism

  • 17. 
    Early one morning, a 50-year-old male patient in a skilled nursing unit, complains that he has a sharp pain in his chest, and he cannot get enough breath. He recently underwent amputation of his foot and is completing an IV antibiotic therapy for a gangrenous chronic wound infection associated with diabetic neuropathy. He is receiving unfractionated heparin subcutaneously for DVT prophylaxis. He denies nausea, vomiting or dizziness but complains about a non-productive cough. His vital signs: BP 132/66; RR 21; T36.5. His cardiovascular system showed regular rate and rhythm and no abnormalities. Laboratory investigations showed: Normal cardiac enzymes Hgb 14g/dL Hct40% Platelets 61x100/mm3 WBC 8x100/mm3. A ventilation-perfusion lung scan showed multiple segmental perfusion defects. Which anticoagulant agent would be most appropriate to initiate anticoagulation for treatment of this patient’s condition?
    • A. 

      Warfarin

    • B. 

      Fractionated heparin

    • C. 

      Drotrecogin alpha

    • D. 

      Dabigatran

    • E. 

      Lepirudin

  • 18. 
    Six young medical students come to the University Health Centre complaining of diarrhea which is pale, greasy and malodorous, with abdominal cramping, gas, and pain. They spent the weekend in a camping site in the mountains and drank untreated stream water. A preliminary diagnosis of malabsorbtion diarrhea was given. Trophozoites were detected in fecal samples by identification of the protozoan antigen using counterimmunoelectrophoresis. Which of the following antiprotozoal drugs would be the most appropriate therapy?
    • A. 

      Diloxanide furoate

    • B. 

      Metronidazole

    • C. 

      Tetracycline

    • D. 

      Stibogluconate

    • E. 

      Chloroquine

  • 19. 
    A 58-year-old man presented to the renal transplant clinic complaining that he had unremitting diarrhea for 3 days. Two months ago he had a cadaveric kidney transplant. In addition to other medications such as gancyclovir, sulfamethoxazole/trimethoprim, the patient is taking immunosuppressive therapy which includes-tacrolimus, prednisone, and mycophenolate mofetil. Selected lab results show: Serum creatinine 1.7mg/dL (0.2-1.0mg/dL) K+: 5.7meq/L Fasting blood sugar: 188mg/dL Which one of his medications is most likely to be responsible for these lab findings?
    • A. 

      Gancyclovir

    • B. 

      Sulfamthoxazole/trimethoprim

    • C. 

      Prednisone

    • D. 

      Tacrolimus

    • E. 

      Mycophenolate mofetil

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