The Ideal Quiz On Antiepileptics

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| By Bwhitt1212
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The Ideal Quiz On Antiepileptics - Quiz

Antiepileptics are a class of drugs that try and prevent rapid, repetitive, stimulation of the brain that causes seizure activity. They should be used carefully with consideration of medication interactions and potential side effects. Test out what you know about this by taking up the quiz below. All the best!


Questions and Answers
  • 1. 

    DRUGS THAT TREAT TONIC CLONIC OR PARTIAL SEIZURES MOST LIKELY WORK HOW?

    • A.

      REDUCTION OF CALCIUM CURRENTS IN THE BODY

    • B.

      DELAY RECOVERY OF SODIUM CURRENTS/CHANNELS FROM ACTIVIATION

    Correct Answer
    B. DELAY RECOVERY OF SODIUM CURRENTS/CHANNELS FROM ACTIVIATION
    Explanation
    The drugs that treat tonic-clonic or partial seizures most likely work by delaying the recovery of sodium currents/channels from activation. This means that these drugs slow down the process of sodium channels returning to their inactive state after being activated. By doing so, they help regulate the excessive electrical activity in the brain that leads to seizures.

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  • 2. 

    DRUGS THAT TREAT ABSENCE SEIZURES GENERALLY WORK HOW?

    • A.

      REDUCTION OF CALCIUM CURRENTS IN THE BODY

    • B.

      DELAY RECOVERY OF SODIUM CHANNELS/CURRENTS FROM ACTIVATION

    Correct Answer
    A. REDUCTION OF CALCIUM CURRENTS IN THE BODY
    Explanation
    The correct answer is "REDUCTION OF CALCIUM CURRENTS IN THE BODY." Drugs that treat absence seizures generally work by reducing the calcium currents in the body. This reduction in calcium currents helps to regulate the excessive electrical activity in the brain that leads to absence seizures. By inhibiting calcium currents, these drugs can effectively control and prevent absence seizures from occurring.

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  • 3. 

    DOES NOT CAUSE POTENTIAL BIRTH DEFECTS IN CHILDREN WHEN MOTHER TAKES DURING PREGNANCY

    • A.

      TEGRETOL

    • B.

      PHENYTOIN

    • C.

      PHENOBARBITAL

    • D.

      DEPAKOTE

    • E.

      NONE OF THESE

    Correct Answer
    E. NONE OF THESE
    Explanation
    The given question is asking for a medication that does not cause potential birth defects in children when taken by the mother during pregnancy. The correct answer is "NONE OF THESE" because all the medications listed (TEGRETOL, PHENYTOIN, PHENOBARBITAL, and DEPAKOTE) are known to have the potential to cause birth defects when taken during pregnancy.

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  • 4. 

    BEST FIRST LINE OPTION FOR ABSENCE SEIZURES

    • A.

      TEGRETOL

    • B.

      PHENYTOIN

    • C.

      PHENOBARBITAL

    • D.

      DEPAKOTE

    • E.

      NONE OF THESE

    Correct Answer
    D. DEPAKOTE
    Explanation
    Depakote is the best first-line option for absence seizures. It is an antiepileptic drug that has been proven to be effective in treating absence seizures. Depakote works by increasing the levels of a neurotransmitter called GABA in the brain, which helps to reduce the abnormal electrical activity that causes seizures. It has been widely used and studied in the treatment of absence seizures and has shown good efficacy and safety. Other options like Tegretol, Phenytoin, and Phenobarbital may be used for other types of seizures but are not considered as effective for absence seizures.

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  • 5. 

    BEST FIRST LINE OPTION FOR TONIC CLONIC SEIZURES

    • A.

      TEGRETOL

    • B.

      PHENYTOIN

    • C.

      PHENOBARBITAL

    • D.

      DEPAKOTE

    • E.

      NONE OF THESE

    Correct Answer
    A. TEGRETOL
    Explanation
    MOST PRETTY EFFECTIVE, BUT ONE HAS LOWER SIDE EFFECTS.

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  • 6. 

    DRUG WITH LEAST RISK OF COGNITIVE IMPAIRMENTS--THOUGH STILL A RISK

    • A.

      TEGRETOL

    • B.

      PHENYTOIN

    • C.

      PHENOBARBITAL

    • D.

      DEPAKOTE

    Correct Answer
    D. DEPAKOTE
    Explanation
    Depakote is the drug with the least risk of cognitive impairments, although there is still a risk associated with its use. This means that compared to Tegretol, Phenytoin, and Phenyobarbital, Depakote is less likely to cause cognitive impairments in individuals who take it. However, it is important to note that there is still a potential risk of cognitive impairments when using Depakote.

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  • 7. 

    THE 2 ANTIEPILEPTICS THAT ARE NOT METABOLISED VIA THE HEPATIC ROUTE ARE _______________ AND ________________

    Correct Answer
    KEPPRA
    NEURONTIN
    GABAPENTIN
    Explanation
    The two antiepileptics that are not metabolized via the hepatic route are Keppra and Neurontin (Gabapentin). This means that these medications are not broken down or processed by the liver in the body. Instead, they are eliminated from the body through other routes, such as renal excretion. This is important to consider when prescribing these medications, as patients with liver dysfunction may still be able to safely use Keppra and Neurontin without the risk of further liver damage or drug interactions.

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  • 8. 

    NOT A SIDE EFFECT ASSOCIATED WITH TEGRETOL

    • A.

      HYPONATREMIA

    • B.

      DROWSINESS

    • C.

      LIVER FAILURE

    • D.

      BLOOD DYSCRASIAS

    Correct Answer
    C. LIVER FAILURE
    Explanation
    Liver failure is not a side effect associated with Tegretol. Tegretol, also known as carbamazepine, is an anticonvulsant and mood stabilizing drug. It is primarily used to treat epilepsy, neuropathic pain, and bipolar disorder. While Tegretol can have various side effects such as drowsiness, hyponatremia (low sodium levels in the blood), and blood dyscrasias (abnormalities in blood cell counts), liver failure is not one of them. Liver failure is a serious medical condition that can be caused by various factors, but it is not directly associated with the use of Tegretol.

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  • 9. 

    SIDE EFFECT NOT ASSOCIATED WITH pHENYTOIN

    • A.

      BEHAVIOR CHANGES

    • B.

      GINGIVAL HYPERPLASIA

    • C.

      RASH

    • D.

      SEDATION

    • E.

      NAUSEA

    Correct Answer
    E. NAUSEA
    Explanation
    Nausea is a side effect that is not commonly associated with the use of phenytoin. Phenytoin is an anticonvulsant medication used to control seizures. While it is known to cause various side effects such as behavior changes, gingival hyperplasia, rash, and sedation, nausea is not typically listed as one of the common side effects.

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  • 10. 

    SIDE EFFECT NOT ASSOCIATED WITH VALPROIC ACID

    • A.

      DEC IN PLATELETS

    • B.

      BLURRED VISION

    • C.

      TREMOR

    • D.

      WEIGHT GAIN

    • E.

      INC IN AMMONIA LEVELS

    Correct Answer
    B. BLURRED VISION
    Explanation
    Blurred vision is not associated with valproic acid. While valproic acid can cause side effects such as decreased platelets, tremor, weight gain, and increased ammonia levels, blurred vision is not commonly reported as a side effect of this medication.

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  • 11. 

    GOOD OPTION TO TREAT TONIC CLONIC SEIZURES

    • A.

      TEGRETOL

    • B.

      PHENYTOIN

    • C.

      VALPROIC ACID

    • D.

      A AND B

    • E.

      ALL OF THESE

    Correct Answer
    E. ALL OF THESE
    Explanation
    All of these options (Tegretol, Phenytoin, and Valproic Acid) are good choices for treating tonic-clonic seizures. Tonic-clonic seizures, also known as grand mal seizures, are a type of generalized seizure that involves loss of consciousness and convulsions. Tegretol (carbamazepine), Phenytoin, and Valproic Acid are all antiepileptic drugs that can effectively control tonic-clonic seizures by stabilizing abnormal electrical activity in the brain. Therefore, all of these options are suitable for treating this type of seizure.

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  • 12. 

    MEDICATION WHERE GETTING THE PATIENT'S ANC IS IMPORTANT

    • A.

      LAMICTAL

    • B.

      TEGRETOL

    • C.

      PHENYTOIN

    • D.

      KEPPRA

    • E.

      NONE OF THESE

    Correct Answer
    B. TEGRETOL
    Explanation
    TEGRETOL is the correct answer because it is a medication used to treat epilepsy and certain types of nerve pain. When prescribing TEGRETOL, it is important to consider the patient's absolute neutrophil count (ANC) because TEGRETOL can cause a decrease in white blood cell count, including neutrophils. Monitoring the ANC is crucial to ensure the patient's safety and to prevent complications related to low white blood cell count.

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  • 13. 

    TRUE OR FALSE--NEURONTIN HAS A LINEAR DOSE TO EFFICACY CURVE

    • A.

      FALSE--THE HIGHER THE DOSE, THE LESS OF AN INCREASE IN EFFICACY

    • B.

      TRUE--AS DOSE INCREASES, THE EFFICACY INCREASES IN A LINEAR FASHION.

    Correct Answer
    A. FALSE--THE HIGHER THE DOSE, THE LESS OF AN INCREASE IN EFFICACY
    Explanation
    The correct answer is FALSE. This means that the statement "The higher the dose, the less of an increase in efficacy" is not true. In reality, as the dose of Neurontin increases, the efficacy does not increase in a linear fashion.

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  • 14. 

    _____ IS THE DRUG ASSOCIATED WITH STEVEN JOHNSONS SYNDROME.

    Correct Answer
    LAMICTAL
    LAMOTRIGINE
    Explanation
    Lamictal (Lamotrigine) is the drug associated with Steven Johnson Syndrome.

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  • 15. 

    BESIDES THE BIG DRUGS FOR SEIZURES--MOST OTHER OPTIONS TREAT WHAT TYPE OF SEIZURES.

    Correct Answer
    PARTIAL SEIZURES
    PARTIAL
    Explanation
    The correct answer is partial seizures. The question is asking about the type of seizures that are treated with options other than the big drugs for seizures. The answer, partial seizures, suggests that there are different types of seizures and that there are alternative treatment options available for partial seizures aside from the commonly used drugs for seizures.

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  • 16. 

    WHAT IS A TRUE STATEMENT ABOUT TRILEPTAL

    • A.

      TO CONVERT FROM TEGRETOL TO TRILEPTAL, MUST MULTIPLY DAILY DOSE BY 1.5X

    • B.

      LESS SIDE EFFECTS THAT PHENYTOIN, VPA, TEGRETOL

    • C.

      IF ALLERGIC TO TEGRETOL, PROBABLY NOT ALLERGIC TO TRILEPTAL.

    • D.

      A AND B

    • E.

      A,B,C

    Correct Answer
    D. A AND B
    Explanation
    Trileptal is a medication that is used to treat seizures. The statement "To convert from Tegretol to Trileptal, must multiply daily dose by 1.5x" is true because Trileptal is a derivative of Tegretol and has a different dosage requirement. The statement "Less side effects than Phenytoin, VPA, Tegretol" is also true because Trileptal is known to have fewer side effects compared to these other medications. Therefore, the correct answer is A and B.

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  • 17. 

    WHAT IS TRUE ABOUT pHENYTOIN.

    • A.

      PHENYTOIN HURTS FOLIC ACID ABSORPTION, AND SHOULD BE TREATED WITH FOLIC ACID WHILE ON MED.

    • B.

      PHENYTOIN SUSPENSION DOSE=PHENYTOIN PO CAPSULE DOSE X 0.92

    • C.

      PHENYTOIN CAPSULES ARE EQUIVALENT TO PHENYTOIN TABLETS

    • D.

      PHENYTOIN CAN WORK WITH ABSENCE SEIZURES

    • E.

      PHENYTOIN CAN WORK WITH GENERALIZED AND PARTIAL SEIZURES.

    Correct Answer
    E. PHENYTOIN CAN WORK WITH GENERALIZED AND PARTIAL SEIZURES.
    Explanation
    Phenytoin is a medication commonly used to treat seizures. It is effective in treating both generalized seizures, which involve the entire brain, and partial seizures, which only affect a specific area of the brain. This means that phenytoin can be used to manage a wide range of seizure disorders.

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  • 18. 

    WHAT IS NOT TRUE ABOUT DEPAKOTE

    • A.

      DRUG WORKS BY DECREASING GABA NT IN THE BODY.

    • B.

      CARNITINE MAY HELP CURB HIGH AMMONIUM LEVELS BY TAKING IT WITH THIS DRUG.

    • C.

      NO CROSS ALLERGY WITH SULFONAMIDES

    • D.

      A AND B

    • E.

      ALL OF ABOVE

    Correct Answer
    A. DRUG WORKS BY DECREASING GABA NT IN THE BODY.
    Explanation
    The statement "DRUG WORKS BY DECREASING GABA NT IN THE BODY" is not true about Depakote. Depakote works by increasing the activity of a neurotransmitter called GABA in the brain, not by decreasing it. GABA is responsible for reducing the activity of nerve cells in the brain, which helps to control seizures and stabilize mood.

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Quiz Review Timeline +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Mar 22, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Apr 18, 2010
    Quiz Created by
    Bwhitt1212

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