Hypersensitivity Reactions Overview

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Quizzes Created: 4044 | Total Attempts: 3,041,032
| Questions: 20 | Updated: Jul 5, 2026
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1. The Arthus reaction is an example of:

Explanation

It is a localized immune complex-mediated reaction.

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About This Quiz
Immunology Quizzes & Trivia

This assessment focuses on hypersensitivity reactions, evaluating your understanding of the different types and their mechanisms. You'll explore key concepts such as the immune response, allergen interactions, and clinical implications. This knowledge is essential for anyone studying immunology or related health fields, providing a solid foundation for further learning and... see moreapplication in real-world scenarios. see less

2.

What first name or nickname would you like us to use?

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2. Which hypersensitivity reaction is antibody-independent?

Explanation

Type IV is mediated by sensitized T cells and macrophages, not antibodies.

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3. Graves disease is classified as:

Explanation

Autoantibodies stimulate the TSH receptor, an antibody-mediated functional disorder.

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4. Bronchial asthma (atopic) is mainly:

Explanation

Atopic asthma is mediated by IgE and mast cells.

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5. Which hypersensitivity is involved in graft rejection?

Explanation

T lymphocytes attack the transplanted tissue.

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6. Contact dermatitis is an example of:

Explanation

Caused by T-cell-mediated inflammation.

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7. Which test is based on Type IV hypersensitivity?

Explanation

It measures delayed T-cell response to tuberculin.

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8. Delayed-type hypersensitivity usually develops after:

Explanation

Hence it is called delayed hypersensitivity.

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9. Type IV hypersensitivity is mediated by:

Explanation

It is a delayed, cell-mediated immune response.

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10. Which complement component acts as an anaphylatoxin?

Explanation

C3a (and C5a) trigger mast cell degranulation.

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11. Immediate hypersensitivity is:

Explanation

Type I reactions occur within minutes and are mediated by IgE.

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12. Classic example of Type III hypersensitivity:

Explanation

Immune complexes deposit in blood vessels, joints, and kidneys.

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13. Type III hypersensitivity is caused by:

Explanation

Antigen-antibody complexes deposit in tissues and activate complement.

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14. Which of the following is NOT a Type II reaction?

Explanation

Serum sickness is a Type III hypersensitivity reaction.

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15. Which disease is an example of Type II hypersensitivity?

Explanation

Antibodies attack basement membranes in lungs and kidneys.

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16. Type II hypersensitivity is mediated by:

Explanation

Antibodies bind directly to cell surface antigens.

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17. Which disease is a Type I hypersensitivity reaction?

Explanation

Allergic rhinitis is an IgE-mediated allergic disease.

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18. Which is the major mediator responsible for itching and vasodilation?

Explanation

Histamine causes vasodilation, increased vascular permeability, and itching.

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19. The most important cell in Type I hypersensitivity is:

Explanation

Cross-linking of IgE on mast cells releases histamine and other mediators.

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20. Which immunoglobulin mediates Type I hypersensitivity?

Explanation

IgE binds to mast cells and basophils, causing degranulation on re-exposure.

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The Arthus reaction is an example of:
Which hypersensitivity reaction is antibody-independent?
Graves disease is classified as:
Bronchial asthma (atopic) is mainly:
Which hypersensitivity is involved in graft rejection?
Contact dermatitis is an example of:
Which test is based on Type IV hypersensitivity?
Delayed-type hypersensitivity usually develops after:
Type IV hypersensitivity is mediated by:
Which complement component acts as an anaphylatoxin?
Immediate hypersensitivity is:
Classic example of Type III hypersensitivity:
Type III hypersensitivity is caused by:
Which of the following is NOT a Type II reaction?
Which disease is an example of Type II hypersensitivity?
Type II hypersensitivity is mediated by:
Which disease is a Type I hypersensitivity reaction?
Which is the major mediator responsible for itching and vasodilation?
The most important cell in Type I hypersensitivity is:
Which immunoglobulin mediates Type I hypersensitivity?
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