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Advanced Mitochondrial Physiology and Cellular Function Quiz

Prepare for your PhD final in cellular and molecular physiology with a focus on mitochondria. This assessment enhances your understanding of mitochondrial functions and their impact on cellular health, targeting key skills for...

Questions: 21 | Attempts: 10 | Last updated: Oct 22, 2025

Sample Question 1
What are the steps involved in mitochondrial symbiosis?

1. Direct fusion of two prokaryotic cells 2. Transfer of genetic material between two prokaryotes 3. Formation of a eukaryotic cell without symbiosis

1. Infolding of plasma membrane2. Engulfing of prokaryote (if heterotrophic then it creates heterotrophic ancestral eukaryote); (if phototrophic then it creates a photosynthetic ancestral eukaryote)

Sample Question 2
What are the three steps for mitochondrial fission? Which two proteins are considered the most important?

1. Initiation of separation site 2. Formation of fusion protein complex (Drp-2 and hFis2) 3. Completion of fusion

1. Initiation of constriction site2. Formation of constriction protein complex(Drp-1 and hFis1)3. Completion of fission.The two most important proteins are hFis1 and Drp-1 (dynamin related protein 1). All of which are GTPases.

1. Inhibition of constriction site 2. Disruption of fission protein complex (Mfn2 and Opa2) 3. Inhibition of fission

1. Activation of fusion protein complex 2. Formation of division protein complex (Mfn1 and Opa1) 3. Completion of synthesis

Sample Question 3
Mention the three steps for mitochondrial fusion. What 2 proteins are the most important?

3. Mitochondrial fusion is a spontaneous process and does not require specific proteins.

1. Mitochondrial fission prevents fusion of mitochondria.

2. Proteins involved in mitochondrial fusion include Ribosomal protein L5 and Nuclear receptor coactivator 7 (NCOA7).

1. Docking or tethering of Mfn12. Outer membrane fusion that requires a change in pH and GTP3. Inner membrane fusion that requires a change in inner membrane potential and high GTP concentration. The most important proteins are mitofusin 1 (Mfn1) and Optic Atrophy 1 (OPA1). All of which are GTPases.

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